rs10832000

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0192 (5772/29966,GnomAD)
G=0164 (4784/29118,TOPMED)
G=0176 (880/5008,1000G)
G=0206 (792/3854,ALSPAC)
G=0197 (729/3708,TWINSUK)
chr11:13228852 (GRCh38.p7) (11p15.3)
AD
GWASdb2
2   publication(s)
See rs on genome
118 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.13228852A>G
GRCh37.p13 chr 11NC_000011.9:g.13250399A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.927G=0.073
1000GenomesAmericanSub694A=0.730G=0.270
1000GenomesEast AsianSub1008A=0.839G=0.161
1000GenomesEuropeSub1006A=0.755G=0.245
1000GenomesGlobalStudy-wide5008A=0.824G=0.176
1000GenomesSouth AsianSub978A=0.800G=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.794G=0.206
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.835G=0.164
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.803G=0.197
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21709609Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer disease.Yesavage JAAm J Geriatr Psychiatry

P-Value

SNP ID p-value Traits Study
rs108320000.00052alcohol dependence20201924

eQTL of rs10832000 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10832000 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr111322875313228821E067-21578
chr111322883313228910E067-21489
chr111322892813230199E067-20200
chr111323021413230357E067-20042
chr111323039913230476E067-19923
chr111323057713230800E067-19599
chr111329766513297875E06747266
chr111322696313227434E068-22965
chr111322746013227670E068-22729
chr111322771913227893E068-22506
chr111322792413228022E068-22377
chr111322802613228084E068-22315
chr111322851513228583E068-21816
chr111322875313228821E068-21578
chr111322883313228910E068-21489
chr111323057713230800E068-19599
chr111323085513230949E068-19450
chr111323113013231219E068-19180
chr111323128913231349E068-19050
chr111323139113231521E068-18878
chr111323745913238679E068-11720
chr111325923713259301E0688838
chr111325933413259711E0688935
chr111329766513297875E06847266
chr111322621113226261E069-24138
chr111322687013226924E069-23475
chr111322696313227434E069-22965
chr111322746013227670E069-22729
chr111322771913227893E069-22506
chr111322851513228583E069-21816
chr111322875313228821E069-21578
chr111322883313228910E069-21489
chr111322892813230199E069-20200
chr111323021413230357E069-20042
chr111323039913230476E069-19923
chr111323057713230800E069-19599
chr111324380913244212E069-6187
chr111324458613245011E069-5388
chr111324517213245305E069-5094
chr111325115713252322E069758
chr111322687013226924E070-23475
chr111322696313227434E070-22965
chr111322746013227670E070-22729
chr111322771913227893E070-22506
chr111322792413228022E070-22377
chr111322892813230199E070-20200
chr111323021413230357E070-20042
chr111323039913230476E070-19923
chr111323057713230800E070-19599
chr111323085513230949E070-19450
chr111324181513241919E070-8480
chr111324195613242003E070-8396
chr111324458613245011E070-5388
chr111324517213245305E070-5094
chr111325019913250435E0700
chr111325052313251129E070124
chr111325115713252322E070758
chr111322687013226924E071-23475
chr111322696313227434E071-22965
chr111322746013227670E071-22729
chr111322771913227893E071-22506
chr111322792413228022E071-22377
chr111322892813230199E071-20200
chr111323021413230357E071-20042
chr111323039913230476E071-19923
chr111323745913238679E071-11720
chr111325115713252322E071758
chr111329766513297875E07147266
chr111322696313227434E072-22965
chr111322746013227670E072-22729
chr111322771913227893E072-22506
chr111323021413230357E072-20042
chr111323039913230476E072-19923
chr111323057713230800E072-19599
chr111323181813231933E072-18466
chr111325115713252322E072758
chr111322696313227434E073-22965
chr111322746013227670E073-22729
chr111322875313228821E073-21578
chr111322883313228910E073-21489
chr111322892813230199E073-20200
chr111323021413230357E073-20042
chr111323039913230476E073-19923
chr111322687013226924E074-23475
chr111322696313227434E074-22965
chr111322746013227670E074-22729
chr111322892813230199E074-20200
chr111323021413230357E074-20042
chr111323039913230476E074-19923
chr111323057713230800E074-19599
chr111322696313227434E081-22965
chr111322746013227670E081-22729
chr111322771913227893E081-22506
chr111322792413228022E081-22377
chr111322892813230199E081-20200
chr111323021413230357E081-20042
chr111323039913230476E081-19923
chr111323057713230800E081-19599
chr111324124413241294E081-9105
chr111324380913244212E081-6187
chr111324458613245011E081-5388
chr111324517213245305E081-5094
chr111325019913250435E0810
chr111325052313251129E081124
chr111325115713252322E081758
chr111322696313227434E082-22965
chr111322746013227670E082-22729
chr111322771913227893E082-22506
chr111323021413230357E082-20042
chr111323039913230476E082-19923
chr111323057713230800E082-19599
chr111323171213231809E082-18590
chr111323181813231933E082-18466
chr111324380913244212E082-6187
chr111324458613245011E082-5388
chr111325052313251129E082124
chr111325115713252322E082758
chr111325629313256373E0825894










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr111325981513259900E0689416