rs10834476

Homo sapiens
T>C
LUZP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0223 (6658/29804,GnomAD)
C=0201 (5877/29118,TOPMED)
C=0256 (1280/5008,1000G)
C=0196 (756/3854,ALSPAC)
C=0198 (734/3708,TWINSUK)
chr11:24752960 (GRCh38.p7) (11p14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.24752960T>C
GRCh37.p13 chr 11NC_000011.9:g.24774506T>C
LUZP2 RefSeqGeneNG_030588.1:g.260991T>C

Gene: LUZP2, leucine zipper protein 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LUZP2 transcript variant 1NM_001009909.3:c.N/AIntron Variant
LUZP2 transcript variant 2NM_001252008.1:c.N/AIntron Variant
LUZP2 transcript variant 3NM_001252010.1:c.N/AIntron Variant
LUZP2 transcript variant X4XM_011520056.2:c.N/AIntron Variant
LUZP2 transcript variant X1XM_017017648.1:c.N/AIntron Variant
LUZP2 transcript variant X2XM_017017649.1:c.N/AIntron Variant
LUZP2 transcript variant X5XM_017017650.1:c.N/AIntron Variant
LUZP2 transcript variant X6XM_017017651.1:c.N/AIntron Variant
LUZP2 transcript variant X3XR_930864.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.772C=0.228
1000GenomesAmericanSub694T=0.820C=0.180
1000GenomesEast AsianSub1008T=0.575C=0.425
1000GenomesEuropeSub1006T=0.804C=0.196
1000GenomesGlobalStudy-wide5008T=0.744C=0.256
1000GenomesSouth AsianSub978T=0.760C=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.804C=0.196
The Genome Aggregation DatabaseAfricanSub8704T=0.781C=0.219
The Genome Aggregation DatabaseAmericanSub832T=0.790C=0.210
The Genome Aggregation DatabaseEast AsianSub1604T=0.550C=0.450
The Genome Aggregation DatabaseEuropeSub18364T=0.792C=0.207
The Genome Aggregation DatabaseGlobalStudy-wide29804T=0.776C=0.223
The Genome Aggregation DatabaseOtherSub300T=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.798C=0.201
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.802C=0.198
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs108344764.77E-05alcohol withdrawal symptoms22072270

eQTL of rs10834476 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10834476 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.