rs10834489

Homo sapiens
C>T
LUZP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0353 (10527/29782,GnomAD)
T=0308 (8978/29118,TOPMED)
T=0375 (1877/5008,1000G)
T=0442 (1704/3854,ALSPAC)
T=0428 (1588/3708,TWINSUK)
chr11:24816255 (GRCh38.p7) (11p14.3)
ND
GWASdb2
2   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.24816255C>T
GRCh37.p13 chr 11NC_000011.9:g.24837801C>T
LUZP2 RefSeqGeneNG_030588.1:g.324286C>T

Gene: LUZP2, leucine zipper protein 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LUZP2 transcript variant 1NM_001009909.3:c.N/AIntron Variant
LUZP2 transcript variant 2NM_001252008.1:c.N/AIntron Variant
LUZP2 transcript variant 3NM_001252010.1:c.N/AIntron Variant
LUZP2 transcript variant X4XM_011520056.2:c.N/AIntron Variant
LUZP2 transcript variant X1XM_017017648.1:c.N/AIntron Variant
LUZP2 transcript variant X2XM_017017649.1:c.N/AIntron Variant
LUZP2 transcript variant X5XM_017017650.1:c.N/AIntron Variant
LUZP2 transcript variant X6XM_017017651.1:c.N/AIntron Variant
LUZP2 transcript variant X3XR_930864.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.865T=0.135
1000GenomesAmericanSub694C=0.630T=0.370
1000GenomesEast AsianSub1008C=0.366T=0.634
1000GenomesEuropeSub1006C=0.580T=0.420
1000GenomesGlobalStudy-wide5008C=0.625T=0.375
1000GenomesSouth AsianSub978C=0.610T=0.390
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.558T=0.442
The Genome Aggregation DatabaseAfricanSub8692C=0.831T=0.169
The Genome Aggregation DatabaseAmericanSub830C=0.610T=0.390
The Genome Aggregation DatabaseEast AsianSub1606C=0.371T=0.629
The Genome Aggregation DatabaseEuropeSub18352C=0.586T=0.414
The Genome Aggregation DatabaseGlobalStudy-wide29782C=0.646T=0.353
The Genome Aggregation DatabaseOtherSub302C=0.590T=0.410
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.691T=0.308
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.572T=0.428
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet
22719919Glutamate and synaptic plasticity systems and smoking behavior: results from a genetic association study.dos Santos VAPLoS One

P-Value

SNP ID p-value Traits Study
rs108344892.5E-05nicotine smoking19268276

eQTL of rs10834489 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10834489 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.