rs10837301

Homo sapiens
A>C
LOC105376637 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0125 (3756/29970,GnomAD)
A==0172 (5035/29118,TOPMED)
A==0156 (782/5008,1000G)
A==0042 (163/3854,ALSPAC)
A==0041 (153/3708,TWINSUK)
chr11:39912418 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.39912418A>C
GRCh37.p13 chr 11NC_000011.9:g.39933968A>C

Gene: LOC105376637, uncharacterized LOC105376637(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376637 transcript variant X1XR_001748194.1:n.N/AIntron Variant
LOC105376637 transcript variant X2XR_001748195.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.390C=0.610
1000GenomesAmericanSub694A=0.050C=0.950
1000GenomesEast AsianSub1008A=0.145C=0.855
1000GenomesEuropeSub1006A=0.035C=0.965
1000GenomesGlobalStudy-wide5008A=0.156C=0.844
1000GenomesSouth AsianSub978A=0.050C=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.042C=0.958
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.172C=0.827
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.041C=0.959
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108373010.00052alcohol dependence20201924

eQTL of rs10837301 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10837301 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.