rs10841707

Homo sapiens
T>A
SLCO1B3 : 500B Downstream Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0202 (6070/29928,GnomAD)
T==0274 (7999/29118,TOPMED)
T==0212 (1061/5008,1000G)
T==0052 (200/3854,ALSPAC)
T==0057 (211/3708,TWINSUK)
chr12:20917203 (GRCh38.p7) (12p12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.20917203T>A
GRCh37.p13 chr 12NC_000012.11:g.21070137T>A
SLCO1B3 RefSeqGeneNG_032071.1:g.111500T>A

Gene: SLCO1B3, solute carrier organic anion transporter family member 1B3(plus strand): 500B Downstream Variant

Molecule type Change Amino acid[Codon] SO Term
SLCO1B3 transcript variant 1NM_019844.3:c.N/ADownstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.620A=0.380
1000GenomesAmericanSub694T=0.060A=0.940
1000GenomesEast AsianSub1008T=0.095A=0.905
1000GenomesEuropeSub1006T=0.062A=0.938
1000GenomesGlobalStudy-wide5008T=0.212A=0.788
1000GenomesSouth AsianSub978T=0.040A=0.960
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.052A=0.948
The Genome Aggregation DatabaseAfricanSub8694T=0.535A=0.465
The Genome Aggregation DatabaseAmericanSub838T=0.060A=0.940
The Genome Aggregation DatabaseEast AsianSub1616T=0.071A=0.929
The Genome Aggregation DatabaseEuropeSub18478T=0.067A=0.932
The Genome Aggregation DatabaseGlobalStudy-wide29928T=0.202A=0.797
The Genome Aggregation DatabaseOtherSub302T=0.060A=0.940
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.274A=0.725
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.057A=0.943
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108417070.000975alcohol dependence21314694

eQTL of rs10841707 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10841707 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.