SNP Detail Info-rs10842176

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0237 (7106/29904,GnomAD)
A=0242 (7046/29118,TOPMED)
A=0289 (1449/5008,1000G)
A=0298 (1148/3854,ALSPAC)
A=0306 (1135/3708,TWINSUK)

Position: chr12:23521323 (GRCh38.p7) (12p12.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 16 Enhancers around

Promoter: 8 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.23521323G>A
GRCh37.p13 chr 12	NC_000012.11:g.23674257G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.922	A=0.078
1000Genomes	American	Sub	694	G=0.750	A=0.250
1000Genomes	East Asian	Sub	1008	G=0.508	A=0.492
1000Genomes	Europe	Sub	1006	G=0.683	A=0.317
1000Genomes	Global	Study-wide	5008	G=0.711	A=0.289
1000Genomes	South Asian	Sub	978	G=0.630	A=0.370
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.702	A=0.298
The Genome Aggregation Database	African	Sub	8710	G=0.899	A=0.101
The Genome Aggregation Database	American	Sub	838	G=0.750	A=0.250
The Genome Aggregation Database	East Asian	Sub	1608	G=0.507	A=0.493
The Genome Aggregation Database	Europe	Sub	18446	G=0.724	A=0.275
The Genome Aggregation Database	Global	Study-wide	29904	G=0.762	A=0.237
The Genome Aggregation Database	Other	Sub	302	G=0.520	A=0.480
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.758	A=0.242
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.694	A=0.306

PMID	Title	Author	Journal
23089632	A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.	Wang JC	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs10842176	4.91E-06	alcohol dependence	23089632

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	23639613	23639711	E081	-34546
chr12	23698964	23699035	E081	24707
chr12	23699286	23699349	E081	25029
chr12	23699532	23700080	E081	25275
chr12	23717191	23717241	E081	42934
chr12	23717335	23717722	E081	43078
chr12	23717810	23717929	E081	43553
chr12	23717971	23718189	E081	43714
chr12	23698964	23699035	E082	24707
chr12	23699286	23699349	E082	25029
chr12	23699532	23700080	E082	25275
chr12	23703122	23703195	E082	28865
chr12	23717191	23717241	E082	42934
chr12	23717335	23717722	E082	43078
chr12	23717810	23717929	E082	43553
chr12	23717971	23718189	E082	43714

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr12	23708440	23708743	E067	34183
chr12	23708868	23708987	E067	34611
chr12	23708440	23708743	E068	34183
chr12	23708868	23708987	E068	34611
chr12	23708440	23708743	E070	34183
chr12	23708868	23708987	E070	34611
chr12	23708440	23708743	E072	34183
chr12	23708868	23708987	E072	34611

rs10842176