rs10845212

Homo sapiens
C>T
LOC101928162 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0100 (2994/29820,GnomAD)
T=0106 (3111/29118,TOPMED)
T=0121 (607/5008,1000G)
T=0104 (399/3854,ALSPAC)
T=0107 (396/3708,TWINSUK)
chr12:10773758 (GRCh38.p7) (12p13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.10773758C>T
GRCh37.p13 chr 12NC_000012.11:g.10926357C>T

Gene: LOC101928162, uncharacterized LOC101928162(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC02366 transcriptNR_120463.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.924T=0.076
1000GenomesAmericanSub694C=0.850T=0.150
1000GenomesEast AsianSub1008C=0.868T=0.132
1000GenomesEuropeSub1006C=0.886T=0.114
1000GenomesGlobalStudy-wide5008C=0.879T=0.121
1000GenomesSouth AsianSub978C=0.840T=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.896T=0.104
The Genome Aggregation DatabaseAfricanSub8678C=0.912T=0.088
The Genome Aggregation DatabaseAmericanSub832C=0.870T=0.130
The Genome Aggregation DatabaseEast AsianSub1588C=0.882T=0.118
The Genome Aggregation DatabaseEuropeSub18420C=0.896T=0.103
The Genome Aggregation DatabaseGlobalStudy-wide29820C=0.899T=0.100
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.893T=0.106
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.893T=0.107
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108452120.000694alcohol dependence21314694

eQTL of rs10845212 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10845212 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr121090334410903401E074-22956
chr121088529210885470E081-40887


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr121090219910903271E067-23086
chr121090219910903271E068-23086
chr121090219910903271E069-23086
chr121090219910903271E071-23086
chr121090219910903271E072-23086
chr121090219910903271E074-23086
chr121090219910903271E082-23086