rs10853771

Homo sapiens
C>T
ZNF225 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0328 (9837/29928,GnomAD)
C==0396 (11543/29118,TOPMED)
C==0442 (2213/5008,1000G)
C==0150 (577/3854,ALSPAC)
C==0159 (589/3708,TWINSUK)
chr19:44125295 (GRCh38.p7) (19q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
29 Enhancers around
60 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.44125295C>T
GRCh37.p13 chr 19NC_000019.9:g.44629448C>T

Gene: ZNF225, zinc finger protein 225(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF225 transcript variant 2NM_001321685.1:c.N/AIntron Variant
ZNF225 transcript variant 1NM_013362.3:c.N/AIntron Variant
ZNF225 transcript variant X1XM_011527285.2:c.N/AIntron Variant
ZNF225 transcript variant X2XM_011527286.2:c.N/AIntron Variant
ZNF225 transcript variant X3XM_005259223.3:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.679T=0.321
1000GenomesAmericanSub694C=0.470T=0.530
1000GenomesEast AsianSub1008C=0.500T=0.500
1000GenomesEuropeSub1006C=0.176T=0.824
1000GenomesGlobalStudy-wide5008C=0.442T=0.558
1000GenomesSouth AsianSub978C=0.310T=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.150T=0.850
The Genome Aggregation DatabaseAfricanSub8694C=0.619T=0.381
The Genome Aggregation DatabaseAmericanSub838C=0.480T=0.520
The Genome Aggregation DatabaseEast AsianSub1610C=0.458T=0.542
The Genome Aggregation DatabaseEuropeSub18484C=0.176T=0.823
The Genome Aggregation DatabaseGlobalStudy-wide29928C=0.328T=0.671
The Genome Aggregation DatabaseOtherSub302C=0.170T=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.396T=0.603
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.159T=0.841
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs108537717.06E-05alcohol consumption23743675

eQTL of rs10853771 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr19:44629448ZNF284ENSG00000186026.6C>T8.0274e-453151Cerebellar_Hemisphere

meQTL of rs10853771 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194467075844670818E06741310
chr194467093344671011E06741485
chr194467104944671115E06741601
chr194461888344619034E068-10414
chr194467075844670818E06841310
chr194467093344671011E06841485
chr194460014844600194E069-29254
chr194460014844600194E070-29254
chr194461888344619034E070-10414
chr194461903744619091E070-10357
chr194461912544619165E070-10283
chr194467075844670818E07041310
chr194467093344671011E07041485
chr194467104944671115E07041601
chr194467187644671938E07042428
chr194461888344619034E071-10414
chr194467075844670818E07141310
chr194467075844670818E07241310
chr194467093344671011E07241485
chr194467075844670818E07441310
chr194467093344671011E07441485
chr194467187644671938E07442428
chr194467075844670818E08141310
chr194467093344671011E08141485
chr194467104944671115E08141601
chr194467187644671938E08142428
chr194460081644600930E082-28518
chr194467093344671011E08241485
chr194467104944671115E08241601









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194459804744599722E067-29726
chr194461592544616789E067-12659
chr194461680644618482E067-10966
chr194464488144646741E06715433
chr194466849844670041E06739050
chr194459781244597885E068-31563
chr194459793544597989E068-31459
chr194459804744599722E068-29726
chr194461578744615827E068-13621
chr194461592544616789E068-12659
chr194461680644618482E068-10966
chr194464474344644803E06815295
chr194464488144646741E06815433
chr194466849844670041E06839050
chr194459804744599722E069-29726
chr194461578744615827E069-13621
chr194461592544616789E069-12659
chr194461680644618482E069-10966
chr194464488144646741E06915433
chr194466849844670041E06939050
chr194459804744599722E070-29726
chr194461592544616789E070-12659
chr194461680644618482E070-10966
chr194464474344644803E07015295
chr194464488144646741E07015433
chr194466849844670041E07039050
chr194459804744599722E071-29726
chr194461578744615827E071-13621
chr194461592544616789E071-12659
chr194461680644618482E071-10966
chr194464474344644803E07115295
chr194464488144646741E07115433
chr194466849844670041E07139050
chr194459804744599722E072-29726
chr194461592544616789E072-12659
chr194461680644618482E072-10966
chr194464474344644803E07215295
chr194464488144646741E07215433
chr194466849844670041E07239050
chr194459804744599722E073-29726
chr194461592544616789E073-12659
chr194461680644618482E073-10966
chr194464488144646741E07315433
chr194466849844670041E07339050
chr194459804744599722E074-29726
chr194461592544616789E074-12659
chr194461680644618482E074-10966
chr194464488144646741E07415433
chr194466849844670041E07439050
chr194459804744599722E081-29726
chr194461592544616789E081-12659
chr194461680644618482E081-10966
chr194464488144646741E08115433
chr194466849844670041E08139050
chr194459804744599722E082-29726
chr194461592544616789E082-12659
chr194461680644618482E082-10966
chr194464474344644803E08215295
chr194464488144646741E08215433
chr194466849844670041E08239050