SNP Detail Info-rs10861184

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

TXNRD1 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0078 (2360/29984,GnomAD)
G=0100 (2937/29118,TOPMED)
G=0081 (406/5008,1000G)
G=0048 (184/3854,ALSPAC)
G=0051 (189/3708,TWINSUK)

Position: chr12:104270315 (GRCh38.p7) (12q23.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 8 Enhancers around

Promoter: 30 Promoters around

Molecule type	Change	Amino acid[Codon]	SO Term
TXNRD1 transcript variant 7	NM_001093771.2:c.	N/A	Intron Variant
TXNRD1 transcript variant 5	NM_001261445.1:c.	N/A	Genic Upstream Transcript Variant
TXNRD1 transcript variant 6	NM_001261446.1:c.	N/A	Genic Upstream Transcript Variant
TXNRD1 transcript variant 4	NM_003330.3:c.	N/A	Genic Upstream Transcript Variant
TXNRD1 transcript variant 1	NM_182729.2:c.	N/A	Genic Upstream Transcript Variant
TXNRD1 transcript variant 2	NM_182742.2:c.	N/A	Genic Upstream Transcript Variant
TXNRD1 transcript variant 3	NM_182743.2:c.	N/A	Genic Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.812	G=0.188
1000Genomes	American	Sub	694	A=0.950	G=0.050
1000Genomes	East Asian	Sub	1008	A=0.978	G=0.022
1000Genomes	Europe	Sub	1006	A=0.955	G=0.045
1000Genomes	Global	Study-wide	5008	A=0.919	G=0.081
1000Genomes	South Asian	Sub	978	A=0.940	G=0.060
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.952	G=0.048
The Genome Aggregation Database	African	Sub	8726	A=0.825	G=0.175
The Genome Aggregation Database	American	Sub	838	A=0.950	G=0.050
The Genome Aggregation Database	East Asian	Sub	1622	A=0.988	G=0.012
The Genome Aggregation Database	Europe	Sub	18498	A=0.959	G=0.041
The Genome Aggregation Database	Global	Study-wide	29984	A=0.921	G=0.078
The Genome Aggregation Database	Other	Sub	300	A=0.950	G=0.050
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.899	G=0.100
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.949	G=0.051

PMID	Title	Author	Journal
19581569	Genome-wide association study of alcohol dependence.	Treutlein J	Arch Gen Psychiatry

SNP ID	p-value	Traits	Study
rs10861184	9.18E-05	alcohol dependence	19581569

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	104683989	104684040	E067	19896
chr12	104679354	104679580	E068	15261
chr12	104698689	104698798	E068	34596
chr12	104698865	104698986	E068	34772
chr12	104670022	104670561	E070	5929
chr12	104683989	104684040	E070	19896
chr12	104686782	104687054	E072	22689
chr12	104670022	104670561	E074	5929

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr12	104679607	104681755	E067	15514
chr12	104681823	104681886	E067	17730
chr12	104682008	104683600	E067	17915
chr12	104679607	104681755	E068	15514
chr12	104681823	104681886	E068	17730
chr12	104682008	104683600	E068	17915
chr12	104679607	104681755	E069	15514
chr12	104681823	104681886	E069	17730
chr12	104682008	104683600	E069	17915
chr12	104679607	104681755	E070	15514
chr12	104681823	104681886	E070	17730
chr12	104682008	104683600	E070	17915
chr12	104679607	104681755	E071	15514
chr12	104681823	104681886	E071	17730
chr12	104682008	104683600	E071	17915
chr12	104679607	104681755	E072	15514
chr12	104681823	104681886	E072	17730
chr12	104682008	104683600	E072	17915
chr12	104679607	104681755	E073	15514
chr12	104681823	104681886	E073	17730
chr12	104682008	104683600	E073	17915
chr12	104679607	104681755	E074	15514
chr12	104681823	104681886	E074	17730
chr12	104682008	104683600	E074	17915
chr12	104679607	104681755	E081	15514
chr12	104681823	104681886	E081	17730
chr12	104682008	104683600	E081	17915
chr12	104679607	104681755	E082	15514
chr12	104681823	104681886	E082	17730
chr12	104682008	104683600	E082	17915

rs10861184