rs10861359

Homo sapiens
C>A
KIAA1033 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0156 (4681/29916,GnomAD)
A=0139 (4057/29118,TOPMED)
A=0166 (833/5008,1000G)
A=0194 (746/3854,ALSPAC)
A=0187 (695/3708,TWINSUK)
chr12:105168213 (GRCh38.p7) (12q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
101 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.105168213C>A
GRCh37.p13 chr 12NC_000012.11:g.105561991C>A
WASHC4 RefSeqGeneNG_034157.1:g.65500C>A

Gene: KIAA1033, KIAA1033(plus strand)

Molecule type Change Amino acid[Codon] SO Term
WASHC4 transcript variant 1NM_001293640.1:c.N/A3 Prime UTR Variant
WASHC4 transcript variant 2NM_015275.2:c.N/A3 Prime UTR Variant
KIAA1033 transcript variant X1XM_011538073.2:c.N/A3 Prime UTR Variant
WASHC4 transcript variant X2XM_011538074.2:c.N/A3 Prime UTR Variant
KIAA1033 transcript variant X7XM_011538077.2:c.N/AGenic Downstream Transcript Variant
KIAA1033 transcript variant X5XM_017019082.1:c.N/AGenic Downstream Transcript Variant
KIAA1033 transcript variant X4XR_001748640.1:n....XR_001748640.1:n.4959C>AC>ANon Coding Transcript Variant
KIAA1033 transcript variant X6XR_001748641.1:n....XR_001748641.1:n.4824C>AC>ANon Coding Transcript Variant
KIAA1033 transcript variant X3XR_001748639.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.971A=0.029
1000GenomesAmericanSub694C=0.760A=0.240
1000GenomesEast AsianSub1008C=0.741A=0.259
1000GenomesEuropeSub1006C=0.811A=0.189
1000GenomesGlobalStudy-wide5008C=0.834A=0.166
1000GenomesSouth AsianSub978C=0.820A=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.806A=0.194
The Genome Aggregation DatabaseAfricanSub8718C=0.945A=0.055
The Genome Aggregation DatabaseAmericanSub838C=0.750A=0.250
The Genome Aggregation DatabaseEast AsianSub1616C=0.744A=0.256
The Genome Aggregation DatabaseEuropeSub18442C=0.809A=0.190
The Genome Aggregation DatabaseGlobalStudy-wide29916C=0.843A=0.156
The Genome Aggregation DatabaseOtherSub302C=0.810A=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.860A=0.139
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.813A=0.187
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108613590.000767alcohol dependence21314694

eQTL of rs10861359 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10861359 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12105585938105586176E06723947
chr12105586182105586226E06724191
chr12105586273105586323E06724282
chr12105586473105586597E06724482
chr12105586704105586949E06724713
chr12105587013105587080E06725022
chr12105587193105587243E06725202
chr12105592716105592913E06730725
chr12105592941105593082E06730950
chr12105593110105593593E06731119
chr12105595096105595445E06733105
chr12105595713105595845E06733722
chr12105596094105596219E06734103
chr12105560606105560767E068-1224
chr12105561232105561423E068-568
chr12105561559105561599E068-392
chr12105585938105586176E06823947
chr12105586182105586226E06824191
chr12105586273105586323E06824282
chr12105586473105586597E06824482
chr12105586704105586949E06824713
chr12105587013105587080E06825022
chr12105587193105587243E06825202
chr12105587429105587469E06825438
chr12105592716105592913E06830725
chr12105592941105593082E06830950
chr12105595096105595445E06833105
chr12105595713105595845E06833722
chr12105596094105596219E06834103
chr12105598656105599340E06836665
chr12105534848105534977E069-27014
chr12105535959105536327E069-25664
chr12105585438105585478E06923447
chr12105585503105585610E06923512
chr12105585654105585704E06923663
chr12105585713105585767E06923722
chr12105585938105586176E06923947
chr12105586182105586226E06924191
chr12105586273105586323E06924282
chr12105586473105586597E06924482
chr12105586704105586949E06924713
chr12105587013105587080E06925022
chr12105587193105587243E06925202
chr12105587429105587469E06925438
chr12105595096105595445E06933105
chr12105595713105595845E06933722
chr12105596094105596219E06934103
chr12105596252105596306E06934261
chr12105535959105536327E071-25664
chr12105585938105586176E07123947
chr12105586704105586949E07124713
chr12105587013105587080E07125022
chr12105587193105587243E07125202
chr12105595096105595445E07133105
chr12105595713105595845E07133722
chr12105596094105596219E07134103
chr12105596252105596306E07134261
chr12105596414105596474E07134423
chr12105596811105596937E07134820
chr12105596967105597017E07134976
chr12105597171105597225E07135180
chr12105534514105534569E072-27422
chr12105535959105536327E072-25664
chr12105560342105560402E072-1589
chr12105560606105560767E072-1224
chr12105561232105561423E072-568
chr12105585503105585610E07223512
chr12105585654105585704E07223663
chr12105585713105585767E07223722
chr12105585938105586176E07223947
chr12105586182105586226E07224191
chr12105586273105586323E07224282
chr12105586473105586597E07224482
chr12105586704105586949E07224713
chr12105587013105587080E07225022
chr12105587193105587243E07225202
chr12105587429105587469E07225438
chr12105592541105592610E07230550
chr12105592716105592913E07230725
chr12105592941105593082E07230950
chr12105593110105593593E07231119
chr12105595096105595445E07233105
chr12105595713105595845E07233722
chr12105596094105596219E07234103
chr12105596252105596306E07234261
chr12105595096105595445E07333105
chr12105595713105595845E07333722
chr12105560342105560402E074-1589
chr12105560606105560767E074-1224
chr12105561232105561423E074-568
chr12105561559105561599E074-392
chr12105586473105586597E07424482
chr12105586704105586949E07424713
chr12105587013105587080E07425022
chr12105587193105587243E07425202
chr12105587429105587469E07425438
chr12105595096105595445E07433105
chr12105595713105595845E07433722
chr12105596094105596219E07434103
chr12105596252105596306E07434261
chr12105596414105596474E07434423