rs10868746

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0088 (2647/29952,GnomAD)
A=0085 (2501/29118,TOPMED)
A=0109 (545/5008,1000G)
A=0077 (297/3854,ALSPAC)
A=0072 (266/3708,TWINSUK)
chr9:88281162 (GRCh38.p7) (9q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
31 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.88281162G>A
GRCh37.p13 chr 9NC_000009.11:g.90896077G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.940A=0.060
1000GenomesAmericanSub694G=0.920A=0.080
1000GenomesEast AsianSub1008G=0.805A=0.195
1000GenomesEuropeSub1006G=0.912A=0.088
1000GenomesGlobalStudy-wide5008G=0.891A=0.109
1000GenomesSouth AsianSub978G=0.870A=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.923A=0.077
The Genome Aggregation DatabaseAfricanSub8712G=0.931A=0.069
The Genome Aggregation DatabaseAmericanSub838G=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1618G=0.805A=0.195
The Genome Aggregation DatabaseEuropeSub18482G=0.914A=0.085
The Genome Aggregation DatabaseGlobalStudy-wide29952G=0.911A=0.088
The Genome Aggregation DatabaseOtherSub302G=0.820A=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.914A=0.085
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.928A=0.072
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108687460.000142alcohol dependence20201924

eQTL of rs10868746 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10868746 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr99085160990852992E067-43085
chr99085301890853075E067-43002
chr99085149390851594E068-44483
chr99085160990852992E068-43085
chr99087279790873389E068-22688
chr99087340790873950E068-22127
chr99087401090874225E068-21852
chr99089562790896370E0680
chr99089637290896482E068295
chr99092422290924393E06828145
chr99085149390851594E069-44483
chr99085160990852992E069-43085
chr99089562790896370E0690
chr99087340790873950E070-22127
chr99085149390851594E071-44483
chr99085160990852992E071-43085
chr99087279790873389E071-22688
chr99087340790873950E071-22127
chr99087401090874225E071-21852
chr99085160990852992E072-43085
chr99089562790896370E0720
chr99085160990852992E073-43085
chr99087279790873389E073-22688
chr99087340790873950E073-22127
chr99087401090874225E073-21852
chr99085149390851594E074-44483
chr99085160990852992E074-43085
chr99087279790873389E074-22688
chr99087340790873950E074-22127
chr99087279790873389E081-22688
chr99085160990852992E082-43085