rs10876740

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0091 (2720/29856,GnomAD)
G=0089 (2597/29118,TOPMED)
G=0135 (677/5008,1000G)
G=0099 (380/3854,ALSPAC)
G=0102 (378/3708,TWINSUK)
chr12:55322580 (GRCh38.p7) (12q13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.55322580A>G
GRCh37.p13 chr 12NC_000012.11:g.55716364A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.986G=0.014
1000GenomesAmericanSub694A=0.740G=0.260
1000GenomesEast AsianSub1008A=0.735G=0.265
1000GenomesEuropeSub1006A=0.907G=0.093
1000GenomesGlobalStudy-wide5008A=0.865G=0.135
1000GenomesSouth AsianSub978A=0.880G=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.901G=0.099
The Genome Aggregation DatabaseAfricanSub8720A=0.967G=0.033
The Genome Aggregation DatabaseAmericanSub830A=0.770G=0.230
The Genome Aggregation DatabaseEast AsianSub1606A=0.760G=0.240
The Genome Aggregation DatabaseEuropeSub18398A=0.901G=0.098
The Genome Aggregation DatabaseGlobalStudy-wide29856A=0.908G=0.091
The Genome Aggregation DatabaseOtherSub302A=0.850G=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.910G=0.089
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.898G=0.102
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs108767404.85E-05alcohol consumption23953852

eQTL of rs10876740 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10876740 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr125572590655726052E0709542
chr125567443455675458E071-40906