SNP Detail Info-rs10876740

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0091 (2720/29856,GnomAD)
G=0089 (2597/29118,TOPMED)
G=0135 (677/5008,1000G)
G=0099 (380/3854,ALSPAC)
G=0102 (378/3708,TWINSUK)

Position: chr12:55322580 (GRCh38.p7) (12q13.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.55322580A>G
GRCh37.p13 chr 12	NC_000012.11:g.55716364A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.986	G=0.014
1000Genomes	American	Sub	694	A=0.740	G=0.260
1000Genomes	East Asian	Sub	1008	A=0.735	G=0.265
1000Genomes	Europe	Sub	1006	A=0.907	G=0.093
1000Genomes	Global	Study-wide	5008	A=0.865	G=0.135
1000Genomes	South Asian	Sub	978	A=0.880	G=0.120
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.901	G=0.099
The Genome Aggregation Database	African	Sub	8720	A=0.967	G=0.033
The Genome Aggregation Database	American	Sub	830	A=0.770	G=0.230
The Genome Aggregation Database	East Asian	Sub	1606	A=0.760	G=0.240
The Genome Aggregation Database	Europe	Sub	18398	A=0.901	G=0.098
The Genome Aggregation Database	Global	Study-wide	29856	A=0.908	G=0.091
The Genome Aggregation Database	Other	Sub	302	A=0.850	G=0.150
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.910	G=0.089
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.898	G=0.102

PMID	Title	Author	Journal
23953852	Genome-wide association studies of maximum number of drinks.	Pan Y	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs10876740	4.85E-05	alcohol consumption	23953852

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	55725906	55726052	E070	9542
chr12	55674434	55675458	E071	-40906

rs10876740