rs10886416

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0132 (3953/29954,GnomAD)
A=0150 (4390/29118,TOPMED)
A=0135 (678/5008,1000G)
A=0111 (426/3854,ALSPAC)
A=0108 (401/3708,TWINSUK)
chr10:119193162 (GRCh38.p7) (10q26.11)
AD
GWASdb2
1   publication(s)
See rs on genome
103 Enhancers around
49 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.119193162C>A
GRCh37.p13 chr 10NC_000010.10:g.120952674C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.748A=0.252
1000GenomesAmericanSub694C=0.900A=0.100
1000GenomesEast AsianSub1008C=0.966A=0.034
1000GenomesEuropeSub1006C=0.902A=0.098
1000GenomesGlobalStudy-wide5008C=0.865A=0.135
1000GenomesSouth AsianSub978C=0.850A=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.889A=0.111
The Genome Aggregation DatabaseAfricanSub8716C=0.765A=0.235
The Genome Aggregation DatabaseAmericanSub838C=0.860A=0.140
The Genome Aggregation DatabaseEast AsianSub1614C=0.973A=0.027
The Genome Aggregation DatabaseEuropeSub18484C=0.907A=0.092
The Genome Aggregation DatabaseGlobalStudy-wide29954C=0.868A=0.132
The Genome Aggregation DatabaseOtherSub302C=0.900A=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.849A=0.150
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.892A=0.108
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs108864160.000459alcohol dependence24277619

eQTL of rs10886416 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10886416 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10120923745120923846E067-28828
chr10120923887120924158E067-28516
chr10120936459120936503E067-16171
chr10120936563120936645E067-16029
chr10120936698120936767E067-15907
chr10120936825120936906E067-15768
chr10120937108120937195E067-15479
chr10120958533120958604E0675859
chr10120958610120959387E0675936
chr10120994708120995218E06742034
chr10120921035120921722E068-30952
chr10120921734120921892E068-30782
chr10120921975120922046E068-30628
chr10120922123120922238E068-30436
chr10120923887120924158E068-28516
chr10120936459120936503E068-16171
chr10120936563120936645E068-16029
chr10120936698120936767E068-15907
chr10120936825120936906E068-15768
chr10120937108120937195E068-15479
chr10120949306120949835E068-2839
chr10120965347120965479E06812673
chr10120921035120921722E069-30952
chr10120921734120921892E069-30782
chr10120921975120922046E069-30628
chr10120922123120922238E069-30436
chr10120923887120924158E069-28516
chr10120936459120936503E069-16171
chr10120936563120936645E069-16029
chr10120936698120936767E069-15907
chr10120936825120936906E069-15768
chr10120937108120937195E069-15479
chr10120949025120949075E069-3599
chr10120949123120949189E069-3485
chr10120949306120949835E069-2839
chr10120958533120958604E0695859
chr10120958610120959387E0695936
chr10120965347120965479E06912673
chr10120994708120995218E06942034
chr10120923887120924158E070-28516
chr10120936459120936503E070-16171
chr10120936563120936645E070-16029
chr10120936698120936767E070-15907
chr10120936825120936906E070-15768
chr10120937108120937195E070-15479
chr10120939090120939151E070-13523
chr10120939273120939363E070-13311
chr10120958610120959387E0705936
chr10120965347120965479E07012673
chr10120996411120998472E07043737
chr10120921035120921722E071-30952
chr10120921734120921892E071-30782
chr10120921975120922046E071-30628
chr10120923887120924158E071-28516
chr10120935750120936315E071-16359
chr10120936459120936503E071-16171
chr10120936563120936645E071-16029
chr10120936698120936767E071-15907
chr10120936825120936906E071-15768
chr10120937108120937195E071-15479
chr10120949306120949835E071-2839
chr10120958533120958604E0715859
chr10120958610120959387E0715936
chr10120965347120965479E07112673
chr10120972678120972757E07120004
chr10120921035120921722E072-30952
chr10120921734120921892E072-30782
chr10120921975120922046E072-30628
chr10120922123120922238E072-30436
chr10120922360120922442E072-30232
chr10120936825120936906E072-15768
chr10120937108120937195E072-15479
chr10120949306120949835E072-2839
chr10120958533120958604E0725859
chr10120921035120921722E073-30952
chr10120921734120921892E073-30782
chr10120921975120922046E073-30628
chr10120923887120924158E073-28516
chr10120936459120936503E073-16171
chr10120936563120936645E073-16029
chr10120965347120965479E07312673
chr10120972277120972572E07319603
chr10120994565120994617E07341891
chr10120994708120995218E07342034
chr10120921035120921722E074-30952
chr10120921734120921892E074-30782
chr10120921975120922046E074-30628
chr10120922123120922238E074-30436
chr10120923745120923846E074-28828
chr10120923887120924158E074-28516
chr10120949306120949835E074-2839
chr10120949881120950240E074-2434
chr10120994708120995218E07442034
chr10120923745120923846E081-28828
chr10120923887120924158E081-28516
chr10120936459120936503E081-16171
chr10120936563120936645E081-16029
chr10120936698120936767E081-15907
chr10120936825120936906E081-15768
chr10120937108120937195E081-15479
chr10120994708120995218E08142034
chr10120936825120936906E082-15768
chr10120937108120937195E082-15479










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10120924190120926345E067-26329
chr10120937200120937411E067-15263
chr10120937437120937577E067-15097
chr10120937620120938961E067-13713
chr10120965497120969839E06712823
chr10120924190120926345E068-26329
chr10120937200120937411E068-15263
chr10120937437120937577E068-15097
chr10120937620120938961E068-13713
chr10120965497120969839E06812823
chr10120924190120926345E069-26329
chr10120937200120937411E069-15263
chr10120937437120937577E069-15097
chr10120937620120938961E069-13713
chr10120965497120969839E06912823
chr10120924190120926345E070-26329
chr10120937200120937411E070-15263
chr10120937437120937577E070-15097
chr10120937620120938961E070-13713
chr10120965497120969839E07012823
chr10120924190120926345E071-26329
chr10120937200120937411E071-15263
chr10120937437120937577E071-15097
chr10120937620120938961E071-13713
chr10120965497120969839E07112823
chr10120924190120926345E072-26329
chr10120937200120937411E072-15263
chr10120937437120937577E072-15097
chr10120937620120938961E072-13713
chr10120965497120969839E07212823
chr10120924190120926345E073-26329
chr10120937200120937411E073-15263
chr10120937437120937577E073-15097
chr10120937620120938961E073-13713
chr10120965497120969839E07312823
chr10120924190120926345E074-26329
chr10120937200120937411E074-15263
chr10120937437120937577E074-15097
chr10120937620120938961E074-13713
chr10120965497120969839E07412823
chr10120924190120926345E081-26329
chr10120937200120937411E081-15263
chr10120937437120937577E081-15097
chr10120937620120938961E081-13713
chr10120924190120926345E082-26329
chr10120937200120937411E082-15263
chr10120937437120937577E082-15097
chr10120937620120938961E082-13713
chr10120965497120969839E08212823