rs10886486

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0132 (3965/29872,GnomAD)
C=0133 (3872/29118,TOPMED)
C=0171 (854/5008,1000G)
C=0114 (439/3854,ALSPAC)
C=0124 (458/3708,TWINSUK)
chr10:119459060 (GRCh38.p7) (10q26.11)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.119459060A>C
GRCh37.p13 chr 10NC_000010.10:g.121218572A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.813C=0.187
1000GenomesAmericanSub694A=0.880C=0.120
1000GenomesEast AsianSub1008A=0.732C=0.268
1000GenomesEuropeSub1006A=0.910C=0.090
1000GenomesGlobalStudy-wide5008A=0.829C=0.171
1000GenomesSouth AsianSub978A=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.886C=0.114
The Genome Aggregation DatabaseAfricanSub8682A=0.821C=0.179
The Genome Aggregation DatabaseAmericanSub838A=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1604A=0.744C=0.256
The Genome Aggregation DatabaseEuropeSub18446A=0.898C=0.102
The Genome Aggregation DatabaseGlobalStudy-wide29872A=0.867C=0.132
The Genome Aggregation DatabaseOtherSub302A=0.910C=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.867C=0.133
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.876C=0.124
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108864860.00031alcohol dependence20201924

eQTL of rs10886486 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10886486 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10121253817121254967E06735245
chr10121254976121255070E06736404
chr10121254976121255070E06836404
chr10121253817121254967E06935245
chr10121181127121182266E070-36306
chr10121182308121182358E070-36214
chr10121182435121182619E070-35953
chr10121253495121253632E07034923
chr10121253817121254967E07035245
chr10121254976121255070E07036404
chr10121255100121255301E07036528
chr10121181127121182266E071-36306
chr10121253817121254967E07135245
chr10121184179121184232E072-34340
chr10121184286121184497E072-34075
chr10121184502121184576E072-33996
chr10121184598121184658E072-33914
chr10121253495121253632E07234923
chr10121253817121254967E07235245
chr10121171630121174291E073-44281
chr10121248829121249663E07430257
chr10121171630121174291E081-44281
chr10121249761121250077E08131189
chr10121251459121252290E08132887
chr10121263230121263284E08244658