rs10886848

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
A=0347 (10393/29912,GnomAD)
A=0404 (11785/29118,TOPMED)
A=0487 (2439/5008,1000G)
A=0200 (770/3854,ALSPAC)
A=0209 (775/3708,TWINSUK)
chr10:121081757 (GRCh38.p7) (10q26.12)
ND
GWASdb2
2   publication(s)
See rs on genome
1 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.121081757C>A
GRCh38.p7 chr 10NC_000010.11:g.121081757C>T
GRCh37.p13 chr 10NC_000010.10:g.122841270C>A
GRCh37.p13 chr 10NC_000010.10:g.122841270C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.342A=0.658
1000GenomesAmericanSub694C=0.570A=0.430
1000GenomesEast AsianSub1008C=0.390A=0.610
1000GenomesEuropeSub1006C=0.791A=0.209
1000GenomesGlobalStudy-wide5008C=0.513A=0.487
1000GenomesSouth AsianSub978C=0.550A=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.800A=0.200
The Genome Aggregation DatabaseAfricanSub8690C=0.402A=0.598
The Genome Aggregation DatabaseAmericanSub832C=0.530A=0.470
The Genome Aggregation DatabaseEast AsianSub1618C=0.447A=0.553
The Genome Aggregation DatabaseEuropeSub18472C=0.792A=0.207
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.652A=0.347
The Genome Aggregation DatabaseOtherSub300C=0.770A=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.595A=0.404
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.791A=0.209
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet
27039371GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans.Chittoor GBMC Genomics

P-Value

SNP ID p-value Traits Study
rs108868481.77E-05alcohol and nictotine co-dependence20158304

eQTL of rs10886848 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10886848 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr105453825054538319E072-12380

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr105451397054514095E068-36604