SNP Detail Info-rs10888505

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0235 (7064/29958,GnomAD)
G=0290 (8463/29118,TOPMED)
G=0290 (1451/5008,1000G)
G=0085 (327/3854,ALSPAC)
G=0093 (346/3708,TWINSUK)

Position: chr1:152652672 (GRCh38.p7) (1q21.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.152652672A>G
GRCh37.p13 chr 1	NC_000001.10:g.152625148A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.394	G=0.606
1000Genomes	American	Sub	694	A=0.830	G=0.170
1000Genomes	East Asian	Sub	1008	A=0.699	G=0.301
1000Genomes	Europe	Sub	1006	A=0.909	G=0.091
1000Genomes	Global	Study-wide	5008	A=0.710	G=0.290
1000Genomes	South Asian	Sub	978	A=0.860	G=0.140
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.915	G=0.085
The Genome Aggregation Database	African	Sub	8716	A=0.489	G=0.511
The Genome Aggregation Database	American	Sub	838	A=0.860	G=0.140
The Genome Aggregation Database	East Asian	Sub	1616	A=0.702	G=0.298
The Genome Aggregation Database	Europe	Sub	18490	A=0.893	G=0.106
The Genome Aggregation Database	Global	Study-wide	29958	A=0.764	G=0.235
The Genome Aggregation Database	Other	Sub	298	A=0.870	G=0.130
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.709	G=0.290
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.907	G=0.093

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10888505	0.000856	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	152652740	152652839	E081	27592
chr1	152653543	152653753	E081	28395
chr1	152654162	152654454	E081	29014

rs10888505