rs10890750

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0432 (12937/29916,GnomAD)
A=0381 (11108/29118,TOPMED)
A=0376 (1882/5008,1000G)
G==0464 (1787/3854,ALSPAC)
G==0451 (1674/3708,TWINSUK)
chr11:107678793 (GRCh38.p7) (11q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
79 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.107678793G>A
GRCh37.p13 chr 11NC_000011.9:g.107549519G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.884A=0.116
1000GenomesAmericanSub694G=0.500A=0.500
1000GenomesEast AsianSub1008G=0.600A=0.400
1000GenomesEuropeSub1006G=0.418A=0.582
1000GenomesGlobalStudy-wide5008G=0.624A=0.376
1000GenomesSouth AsianSub978G=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.464A=0.536
The Genome Aggregation DatabaseAfricanSub8706G=0.830A=0.170
The Genome Aggregation DatabaseAmericanSub834G=0.500A=0.500
The Genome Aggregation DatabaseEast AsianSub1608G=0.576A=0.424
The Genome Aggregation DatabaseEuropeSub18466G=0.446A=0.553
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.567A=0.432
The Genome Aggregation DatabaseOtherSub302G=0.510A=0.490
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.618A=0.381
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.451A=0.549
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108907507.68E-05alcohol dependence21314694

eQTL of rs10890750 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10890750 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11107570137107571073E06720618
chr11107535804107536096E068-13423
chr11107589722107590148E06840203
chr11107590152107591478E06840633
chr11107535804107536096E069-13423
chr11107537921107537994E069-11525
chr11107535804107536096E070-13423
chr11107536280107536343E070-13176
chr11107584274107584331E07034755
chr11107584581107584649E07035062
chr11107537581107537748E072-11771
chr11107537760107537885E072-11634
chr11107537921107537994E072-11525
chr11107535804107536096E074-13423
chr11107500437107500509E081-49010
chr11107500540107500594E081-48925
chr11107500663107500743E081-48776
chr11107502216107502298E081-47221
chr11107547175107547341E081-2178
chr11107547446107547521E081-1998
chr11107547591107547645E081-1874
chr11107547673107547723E081-1796
chr11107547952107548002E081-1517
chr11107548762107549007E081-512
chr11107549805107549855E081286
chr11107550031107550111E081512
chr11107550156107550206E081637
chr11107559433107559526E0819914
chr11107559598107559648E08110079
chr11107559679107560733E08110160
chr11107560752107560831E08111233
chr11107560876107560954E08111357
chr11107561055107561105E08111536
chr11107561270107561339E08111751
chr11107561376107562214E08111857
chr11107562228107562379E08112709
chr11107562427107562477E08112908
chr11107562541107562627E08113022
chr11107570137107571073E08120618
chr11107571379107571538E08121860
chr11107571795107571849E08122276
chr11107571930107571985E08122411
chr11107572970107573032E08123451
chr11107573040107573173E08123521
chr11107573176107573239E08123657
chr11107573447107573732E08123928
chr11107573857107573917E08124338
chr11107573993107574054E08124474
chr11107576638107576754E08127119
chr11107576835107576923E08127316
chr11107576925107577107E08127406
chr11107578569107579153E08129050
chr11107579166107579311E08129647
chr11107584274107584331E08134755
chr11107584581107584649E08135062
chr11107584993107585043E08135474
chr11107589722107590148E08140203
chr11107590152107591478E08140633
chr11107535804107536096E082-13423
chr11107546958107547042E082-2477
chr11107547175107547341E082-2178
chr11107547446107547521E082-1998
chr11107547591107547645E082-1874
chr11107547673107547723E082-1796
chr11107549805107549855E082286
chr11107559598107559648E08210079
chr11107559679107560733E08210160
chr11107560752107560831E08211233
chr11107560876107560954E08211357
chr11107561055107561105E08211536
chr11107561270107561339E08211751
chr11107561376107562214E08211857
chr11107562228107562379E08212709
chr11107570137107571073E08220618
chr11107584274107584331E08234755
chr11107584581107584649E08235062
chr11107584993107585043E08235474
chr11107589722107590148E08240203
chr11107590152107591478E08240633








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11107581701107581751E08232182
chr11107581833107581900E08232314
chr11107582137107582263E08232618
chr11107582268107582336E08232749
chr11107582556107583520E08233037