rs10891936

Homo sapiens
G>A / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
A=0359 (10725/29802,GnomAD)
A=0316 (9209/29118,TOPMED)
A=0347 (1738/5008,1000G)
A=0490 (1889/3854,ALSPAC)
A=0492 (1826/3708,TWINSUK)
chr11:116255743 (GRCh38.p7) (11q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
338 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.116255743G>A
GRCh38.p7 chr 11NC_000011.10:g.116255743G>T
GRCh37.p13 chr 11NC_000011.9:g.116126460G>A
GRCh37.p13 chr 11NC_000011.9:g.116126460G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.982A=0.018
1000GenomesAmericanSub694G=0.610A=0.390
1000GenomesEast AsianSub1008G=0.577A=0.423
1000GenomesEuropeSub1006G=0.501A=0.499
1000GenomesGlobalStudy-wide5008G=0.653A=0.347
1000GenomesSouth AsianSub978G=0.470A=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.510A=0.490
The Genome Aggregation DatabaseAfricanSub8670G=0.906A=0.094
The Genome Aggregation DatabaseAmericanSub830G=0.620A=0.380
The Genome Aggregation DatabaseEast AsianSub1608G=0.599A=0.401
The Genome Aggregation DatabaseEuropeSub18392G=0.521A=0.478
The Genome Aggregation DatabaseGlobalStudy-wide29802G=0.640A=0.359
The Genome Aggregation DatabaseOtherSub302G=0.530A=0.470
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.683A=0.316
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.508A=0.492
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108919360.00033alcohol dependence(early age of onset)20201924
rs108919360.00048alcohol dependence20201924

eQTL of rs10891936 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10891936 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11112704830112705527E067-45102
chr11112705839112705926E067-44703
chr11112706079112706129E067-44500
chr11112706266112706329E067-44300
chr11112706340112706429E067-44200
chr11112706498112706772E067-43857
chr11112706834112706964E067-43665
chr11112707109112707244E067-43385
chr11112707357112707445E067-43184
chr11112707553112707603E067-43026
chr11112708020112708122E067-42507
chr11112708241112708422E067-42207
chr11112708453112708671E067-41958
chr11112708731112708838E067-41791
chr11112713633112713683E067-36946
chr11112713965112714075E067-36554
chr11112714927112715007E067-35622
chr11112715062112715764E067-34865
chr11112715898112716011E067-34618
chr11112716194112716320E067-34309
chr11112716506112716572E067-34057
chr11112748245112748645E067-1984
chr11112748802112749020E067-1609
chr11112749027112749351E067-1278
chr11112752891112752976E0672262
chr11112753013112753204E0672384
chr11112753252112754010E0672623
chr11112754021112754270E0673392
chr11112754339112754389E0673710
chr11112754873112754968E0674244
chr11112756002112756052E0675373
chr11112760233112760277E0679604
chr11112760321112760454E0679692
chr11112761136112761177E06710507
chr11112765354112765459E06714725
chr11112765482112765577E06714853
chr11112765728112765778E06715099
chr11112766360112766562E06715731
chr11112772802112772909E06722173
chr11112773025112773891E06722396
chr11112774098112774512E06723469
chr11112775333112775433E06724704
chr11112704830112705527E068-45102
chr11112705839112705926E068-44703
chr11112706079112706129E068-44500
chr11112706266112706329E068-44300
chr11112706340112706429E068-44200
chr11112706498112706772E068-43857
chr11112708020112708122E068-42507
chr11112708241112708422E068-42207
chr11112708453112708671E068-41958
chr11112708731112708838E068-41791
chr11112708864112708904E068-41725
chr11112708936112709155E068-41474
chr11112713965112714075E068-36554
chr11112714927112715007E068-35622
chr11112715062112715764E068-34865
chr11112715898112716011E068-34618
chr11112716194112716320E068-34309
chr11112716506112716572E068-34057
chr11112734173112735911E068-14718
chr11112748245112748645E068-1984
chr11112748802112749020E068-1609
chr11112749027112749351E068-1278
chr11112752891112752976E0682262
chr11112753013112753204E0682384
chr11112753252112754010E0682623
chr11112754021112754270E0683392
chr11112754339112754389E0683710
chr11112754873112754968E0684244
chr11112754990112755419E0684361
chr11112755498112755548E0684869
chr11112755711112755877E0685082
chr11112756002112756052E0685373
chr11112760233112760277E0689604
chr11112760321112760454E0689692
chr11112761136112761177E06810507
chr11112766360112766562E06815731
chr11112772802112772909E06822173
chr11112774098112774512E06823469
chr11112775333112775433E06824704
chr11112704384112704438E069-46191
chr11112704526112704576E069-46053
chr11112704830112705527E069-45102
chr11112705839112705926E069-44703
chr11112706079112706129E069-44500
chr11112706266112706329E069-44300
chr11112706340112706429E069-44200
chr11112706498112706772E069-43857
chr11112706834112706964E069-43665
chr11112707109112707244E069-43385
chr11112707357112707445E069-43184
chr11112707553112707603E069-43026
chr11112708020112708122E069-42507
chr11112708241112708422E069-42207
chr11112708453112708671E069-41958
chr11112708731112708838E069-41791
chr11112712947112713147E069-37482
chr11112713269112713319E069-37310
chr11112713454112713563E069-37066
chr11112713633112713683E069-36946
chr11112713965112714075E069-36554
chr11112714927112715007E069-35622
chr11112715062112715764E069-34865
chr11112715898112716011E069-34618
chr11112716194112716320E069-34309
chr11112716506112716572E069-34057
chr11112734173112735911E069-14718
chr11112748245112748645E069-1984
chr11112748802112749020E069-1609
chr11112749027112749351E069-1278
chr11112751805112751921E0691176
chr11112752891112752976E0692262
chr11112753013112753204E0692384
chr11112753252112754010E0692623
chr11112754021112754270E0693392
chr11112754339112754389E0693710
chr11112754873112754968E0694244
chr11112756002112756052E0695373
chr11112760233112760277E0699604
chr11112760321112760454E0699692
chr11112761136112761177E06910507
chr11112765354112765459E06914725
chr11112765482112765577E06914853
chr11112765728112765778E06915099
chr11112766360112766562E06915731
chr11112772802112772909E06922173
chr11112774098112774512E06923469
chr11112775333112775433E06924704
chr11112700791112701060E070-49569
chr11112701137112701215E070-49414
chr11112704830112705527E070-45102
chr11112705839112705926E070-44703
chr11112706079112706129E070-44500
chr11112706266112706329E070-44300
chr11112706340112706429E070-44200
chr11112706498112706772E070-43857
chr11112706834112706964E070-43665
chr11112707109112707244E070-43385
chr11112707357112707445E070-43184
chr11112734173112735911E070-14718
chr11112747481112747590E070-3039
chr11112747644112747761E070-2868
chr11112747970112748020E070-2609
chr11112748105112748186E070-2443
chr11112748245112748645E070-1984
chr11112751656112751708E0701027
chr11112751714112751774E0701085
chr11112751805112751921E0701176
chr11112766360112766562E07015731
chr11112773025112773891E07022396
chr11112774098112774512E07023469
chr11112704830112705527E071-45102
chr11112705839112705926E071-44703
chr11112706079112706129E071-44500
chr11112706266112706329E071-44300
chr11112706340112706429E071-44200
chr11112706498112706772E071-43857
chr11112706834112706964E071-43665
chr11112707553112707603E071-43026
chr11112708020112708122E071-42507
chr11112708241112708422E071-42207
chr11112708453112708671E071-41958
chr11112708731112708838E071-41791
chr11112713633112713683E071-36946
chr11112713965112714075E071-36554
chr11112714927112715007E071-35622
chr11112715062112715764E071-34865
chr11112715898112716011E071-34618
chr11112716194112716320E071-34309
chr11112716506112716572E071-34057
chr11112716720112716806E071-33823
chr11112734173112735911E071-14718
chr11112747970112748020E071-2609
chr11112748105112748186E071-2443
chr11112748245112748645E071-1984
chr11112748802112749020E071-1609
chr11112749027112749351E071-1278
chr11112753013112753204E0712384
chr11112753252112754010E0712623
chr11112754021112754270E0713392
chr11112754339112754389E0713710
chr11112754873112754968E0714244
chr11112756002112756052E0715373
chr11112760233112760277E0719604
chr11112760321112760454E0719692
chr11112761136112761177E07110507
chr11112766360112766562E07115731
chr11112772802112772909E07122173
chr11112773025112773891E07122396
chr11112774098112774512E07123469
chr11112775333112775433E07124704
chr11112782606112782990E07131977
chr11112704830112705527E072-45102
chr11112705839112705926E072-44703
chr11112706079112706129E072-44500
chr11112706266112706329E072-44300
chr11112706340112706429E072-44200
chr11112706498112706772E072-43857
chr11112706834112706964E072-43665
chr11112707109112707244E072-43385
chr11112707357112707445E072-43184
chr11112707553112707603E072-43026
chr11112708020112708122E072-42507
chr11112708241112708422E072-42207
chr11112712947112713147E072-37482
chr11112713269112713319E072-37310
chr11112713454112713563E072-37066
chr11112713633112713683E072-36946
chr11112713965112714075E072-36554
chr11112714927112715007E072-35622
chr11112715062112715764E072-34865
chr11112715898112716011E072-34618
chr11112716194112716320E072-34309
chr11112747481112747590E072-3039
chr11112747644112747761E072-2868
chr11112747970112748020E072-2609
chr11112748105112748186E072-2443
chr11112748245112748645E072-1984
chr11112748802112749020E072-1609
chr11112749027112749351E072-1278
chr11112751805112751921E0721176
chr11112752891112752976E0722262
chr11112753013112753204E0722384
chr11112753252112754010E0722623
chr11112754021112754270E0723392
chr11112754339112754389E0723710
chr11112754873112754968E0724244
chr11112754990112755419E0724361
chr11112755711112755877E0725082
chr11112760233112760277E0729604
chr11112760321112760454E0729692
chr11112766360112766562E07215731
chr11112772802112772909E07222173
chr11112773025112773891E07222396
chr11112774098112774512E07223469
chr11112775333112775433E07224704
chr11112776246112776401E07225617
chr11112704830112705527E073-45102
chr11112705839112705926E073-44703
chr11112706079112706129E073-44500
chr11112706266112706329E073-44300
chr11112706340112706429E073-44200
chr11112706498112706772E073-43857
chr11112706834112706964E073-43665
chr11112707109112707244E073-43385
chr11112708020112708122E073-42507
chr11112714927112715007E073-35622
chr11112715062112715764E073-34865
chr11112734173112735911E073-14718
chr11112748245112748645E073-1984
chr11112748802112749020E073-1609
chr11112749027112749351E073-1278
chr11112752891112752976E0732262
chr11112753013112753204E0732384
chr11112753252112754010E0732623
chr11112754873112754968E0734244
chr11112755711112755877E0735082
chr11112756002112756052E0735373
chr11112772802112772909E07322173
chr11112773025112773891E07322396
chr11112774098112774512E07323469
chr11112775333112775433E07324704
chr11112704384112704438E074-46191
chr11112704526112704576E074-46053
chr11112704830112705527E074-45102
chr11112705839112705926E074-44703
chr11112706079112706129E074-44500
chr11112706266112706329E074-44300
chr11112706340112706429E074-44200
chr11112707553112707603E074-43026
chr11112708020112708122E074-42507
chr11112708241112708422E074-42207
chr11112708453112708671E074-41958
chr11112708731112708838E074-41791
chr11112708864112708904E074-41725
chr11112708936112709155E074-41474
chr11112713633112713683E074-36946
chr11112713965112714075E074-36554
chr11112714927112715007E074-35622
chr11112715062112715764E074-34865
chr11112715898112716011E074-34618
chr11112716194112716320E074-34309
chr11112716506112716572E074-34057
chr11112748245112748645E074-1984
chr11112748802112749020E074-1609
chr11112749027112749351E074-1278
chr11112751805112751921E0741176
chr11112752891112752976E0742262
chr11112753013112753204E0742384
chr11112753252112754010E0742623
chr11112754021112754270E0743392
chr11112754339112754389E0743710
chr11112754873112754968E0744244
chr11112754990112755419E0744361
chr11112755498112755548E0744869
chr11112755593112755672E0744964
chr11112755711112755877E0745082
chr11112756002112756052E0745373
chr11112760233112760277E0749604
chr11112760321112760454E0749692
chr11112761136112761177E07410507
chr11112766360112766562E07415731
chr11112772802112772909E07422173
chr11112773025112773891E07422396
chr11112774098112774512E07423469
chr11112775333112775433E07424704
chr11112782606112782990E07431977
chr11112704830112705527E081-45102
chr11112705839112705926E081-44703
chr11112706079112706129E081-44500
chr11112706266112706329E081-44300
chr11112706340112706429E081-44200
chr11112706498112706772E081-43857
chr11112706834112706964E081-43665
chr11112707109112707244E081-43385
chr11112748245112748645E081-1984
chr11112748802112749020E081-1609
chr11112749027112749351E081-1278
chr11112751805112751921E0811176
chr11112752891112752976E0812262
chr11112753013112753204E0812384
chr11112704830112705527E082-45102
chr11112705839112705926E082-44703
chr11112706079112706129E082-44500
chr11112706266112706329E082-44300
chr11112706340112706429E082-44200
chr11112706498112706772E082-43857
chr11112706834112706964E082-43665
chr11112707109112707244E082-43385
chr11112707357112707445E082-43184
chr11112747970112748020E082-2609
chr11112748105112748186E082-2443
chr11112748245112748645E082-1984
chr11112748802112749020E082-1609
chr11112749027112749351E082-1278
chr11112751805112751921E0821176
chr11112753013112753204E0822384










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11112752001112752738E0671372
chr11112752001112752738E0681372
chr11112752001112752738E0691372
chr11112752001112752738E0701372
chr11112752001112752738E0711372
chr11112752001112752738E0721372
chr11112752001112752738E0731372
chr11112752001112752738E0741372
chr11112752001112752738E0811372
chr11112752001112752738E0821372