rs10891937

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0479 (14319/29886,GnomAD)
A=0498 (14523/29118,TOPMED)
G==0480 (2403/5008,1000G)
G==0392 (1509/3854,ALSPAC)
G==0395 (1466/3708,TWINSUK)
chr11:116256087 (GRCh38.p7) (11q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
178 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.116256087G>A
GRCh37.p13 chr 11NC_000011.9:g.116126804G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.652A=0.348
1000GenomesAmericanSub694G=0.510A=0.490
1000GenomesEast AsianSub1008G=0.481A=0.519
1000GenomesEuropeSub1006G=0.386A=0.614
1000GenomesGlobalStudy-wide5008G=0.480A=0.520
1000GenomesSouth AsianSub978G=0.320A=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.392A=0.608
The Genome Aggregation DatabaseAfricanSub8674G=0.607A=0.393
The Genome Aggregation DatabaseAmericanSub834G=0.560A=0.440
The Genome Aggregation DatabaseEast AsianSub1616G=0.487A=0.513
The Genome Aggregation DatabaseEuropeSub18460G=0.415A=0.584
The Genome Aggregation DatabaseGlobalStudy-wide29886G=0.479A=0.520
The Genome Aggregation DatabaseOtherSub302G=0.410A=0.590
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.501A=0.498
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.395A=0.605
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs108919370.00016alcohol dependence(early age of onset)20201924
rs108919370.00086alcohol dependence20201924

eQTL of rs10891937 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10891937 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11116089825116089984E067-36820
chr11116095592116095644E067-31160
chr11116095694116095765E067-31039
chr11116095804116096349E067-30455
chr11116095592116095644E068-31160
chr11116095694116095765E068-31039
chr11116099906116101440E068-25364
chr11116127862116128078E0681058
chr11116133891116134128E0687087
chr11116089720116089802E069-37002
chr11116089825116089984E069-36820
chr11116090062116090437E069-36367
chr11116095189116095526E069-31278
chr11116095592116095644E069-31160
chr11116095694116095765E069-31039
chr11116146992116148073E06920188
chr11116087692116088108E070-38696
chr11116090062116090437E070-36367
chr11116090459116090536E070-36268
chr11116094790116094855E070-31949
chr11116095037116095119E070-31685
chr11116095189116095526E070-31278
chr11116095592116095644E070-31160
chr11116095694116095765E070-31039
chr11116095804116096349E070-30455
chr11116096354116096463E070-30341
chr11116096588116096789E070-30015
chr11116099356116099477E070-27327
chr11116099519116099573E070-27231
chr11116099906116101440E070-25364
chr11116101508116101564E070-25240
chr11116101588116101684E070-25120
chr11116101846116101933E070-24871
chr11116102142116102668E070-24136
chr11116102787116102841E070-23963
chr11116103046116103101E070-23703
chr11116103133116103547E070-23257
chr11116103566116103710E070-23094
chr11116103799116103986E070-22818
chr11116104186116104374E070-22430
chr11116104419116104679E070-22125
chr11116113708116113782E070-13022
chr11116113863116113913E070-12891
chr11116113940116113990E070-12814
chr11116114823116114863E070-11941
chr11116114872116114984E070-11820
chr11116114994116115094E070-11710
chr11116115422116115658E070-11146
chr11116115669116115940E070-10864
chr11116120645116120695E070-6109
chr11116133279116133345E0706475
chr11116133426116133511E0706622
chr11116133516116133566E0706712
chr11116133891116134128E0707087
chr11116134195116134902E0707391
chr11116134996116135069E0708192
chr11116136393116136443E0709589
chr11116136598116136687E0709794
chr11116136712116136759E0709908
chr11116137006116137218E07010202
chr11116137366116137446E07010562
chr11116137818116137899E07011014
chr11116138000116138126E07011196
chr11116143100116143199E07016296
chr11116144276116144347E07017472
chr11116144512116144570E07017708
chr11116144870116144920E07018066
chr11116145010116145973E07018206
chr11116146041116146091E07019237
chr11116146122116146179E07019318
chr11116146455116146643E07019651
chr11116146827116146990E07020023
chr11116146992116148073E07020188
chr11116148123116148187E07021319
chr11116149494116149683E07022690
chr11116149740116149823E07022936
chr11116150195116150728E07023391
chr11116150970116151021E07024166
chr11116155376116155466E07028572
chr11116155756116156105E07028952
chr11116156163116156293E07029359
chr11116171030116171074E07044226
chr11116171148116171273E07044344
chr11116171617116171667E07044813
chr11116095037116095119E071-31685
chr11116095189116095526E071-31278
chr11116095592116095644E071-31160
chr11116095694116095765E071-31039
chr11116095804116096349E071-30455
chr11116095592116095644E072-31160
chr11116095694116095765E072-31039
chr11116095804116096349E072-30455
chr11116133891116134128E0727087
chr11116089720116089802E073-37002
chr11116089825116089984E073-36820
chr11116090062116090437E073-36367
chr11116090459116090536E073-36268
chr11116094656116094732E073-32072
chr11116094790116094855E073-31949
chr11116095189116095526E073-31278
chr11116095592116095644E073-31160
chr11116095694116095765E073-31039
chr11116136712116136759E0739908
chr11116146827116146990E07320023
chr11116146992116148073E07320188
chr11116078972116079022E081-47782
chr11116090062116090437E081-36367
chr11116090459116090536E081-36268
chr11116095189116095526E081-31278
chr11116095592116095644E081-31160
chr11116095694116095765E081-31039
chr11116095804116096349E081-30455
chr11116096354116096463E081-30341
chr11116096588116096789E081-30015
chr11116099906116101440E081-25364
chr11116101508116101564E081-25240
chr11116101588116101684E081-25120
chr11116101846116101933E081-24871
chr11116120645116120695E081-6109
chr11116133426116133511E0816622
chr11116133516116133566E0816712
chr11116133891116134128E0817087
chr11116134195116134902E0817391
chr11116134996116135069E0818192
chr11116141106116141156E08114302
chr11116141462116141717E08114658
chr11116141981116142083E08115177
chr11116142476116142516E08115672
chr11116143100116143199E08116296
chr11116144276116144347E08117472
chr11116144512116144570E08117708
chr11116144870116144920E08118066
chr11116145010116145973E08118206
chr11116146041116146091E08119237
chr11116146122116146179E08119318
chr11116146455116146643E08119651
chr11116146827116146990E08120023
chr11116146992116148073E08120188
chr11116149494116149683E08122690
chr11116149740116149823E08122936
chr11116150195116150728E08123391
chr11116150970116151021E08124166
chr11116155376116155466E08128572
chr11116155756116156105E08128952
chr11116156163116156293E08129359
chr11116156915116156965E08130111
chr11116158328116158609E08131524
chr11116158700116158867E08131896
chr11116172408116172503E08145604
chr11116173358116173443E08146554
chr11116173500116174072E08146696
chr11116090062116090437E082-36367
chr11116090459116090536E082-36268
chr11116095189116095526E082-31278
chr11116095592116095644E082-31160
chr11116095694116095765E082-31039
chr11116095804116096349E082-30455
chr11116096354116096463E082-30341
chr11116096588116096789E082-30015
chr11116099906116101440E082-25364
chr11116101508116101564E082-25240
chr11116101588116101684E082-25120
chr11116133891116134128E0827087
chr11116134195116134902E0827391
chr11116136598116136687E0829794
chr11116136712116136759E0829908
chr11116137006116137218E08210202
chr11116137366116137446E08210562
chr11116144512116144570E08217708
chr11116144870116144920E08218066
chr11116145010116145973E08218206
chr11116146041116146091E08219237
chr11116146122116146179E08219318
chr11116155756116156105E08228952
chr11116156163116156293E08229359
chr11116156915116156965E08230111
chr11116173358116173443E08246554
chr11116173500116174072E08246696