rs10899187

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0334 (9989/29838,GnomAD)
T==0354 (10315/29118,TOPMED)
T==0425 (2127/5008,1000G)
T==0194 (749/3854,ALSPAC)
T==0183 (680/3708,TWINSUK)
chr11:76255283 (GRCh38.p7) (11q13.5)
AD
GWASdb2
1   publication(s)
See rs on genome
45 Enhancers around
18 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.76255283T>C
GRCh37.p13 chr 11NC_000011.9:g.75966327T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.492C=0.508
1000GenomesAmericanSub694T=0.420C=0.580
1000GenomesEast AsianSub1008T=0.622C=0.378
1000GenomesEuropeSub1006T=0.219C=0.781
1000GenomesGlobalStudy-wide5008T=0.425C=0.575
1000GenomesSouth AsianSub978T=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.194C=0.806
The Genome Aggregation DatabaseAfricanSub8666T=0.470C=0.530
The Genome Aggregation DatabaseAmericanSub834T=0.390C=0.610
The Genome Aggregation DatabaseEast AsianSub1610T=0.591C=0.409
The Genome Aggregation DatabaseEuropeSub18428T=0.248C=0.751
The Genome Aggregation DatabaseGlobalStudy-wide29838T=0.334C=0.665
The Genome Aggregation DatabaseOtherSub300T=0.190C=0.810
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.354C=0.645
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.183C=0.817
PMID Title Author Journal
22481050Genetic influences on craving for alcohol.Agrawal AAddict Behav

P-Value

SNP ID p-value Traits Study
rs108991872.81E-05alcohol craving with or without dependence22481050

eQTL of rs10899187 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10899187 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr117597402175974075E0677694
chr117597437475974556E0678047
chr117597473675975113E0678409
chr117592758175927924E069-38403
chr117592798675928089E069-38238
chr117594431175944550E069-21777
chr117594458675944657E069-21670
chr117596447475964749E069-1578
chr117596484475964894E069-1433
chr117596500975965087E069-1240
chr117597402175974075E0697694
chr117597437475974556E0698047
chr117597473675975113E0698409
chr117598034075982338E07014013
chr117592702775927262E071-39065
chr117592730975927531E071-38796
chr117592758175927924E071-38403
chr117597402175974075E0717694
chr117597437475974556E0718047
chr117597473675975113E0718409
chr117596447475964749E072-1578
chr117596484475964894E072-1433
chr117597402175974075E0727694
chr117597437475974556E0728047
chr117597473675975113E0728409
chr117597357775973632E0747250
chr117597402175974075E0747694
chr117597437475974556E0748047
chr117597473675975113E0748409
chr117595488775955130E081-11197
chr117596750375967728E0811176
chr117596776575968075E0811438
chr117596815175968433E0811824
chr117596844775968802E0812120
chr117597111475971179E0814787
chr117597148675971584E0815159
chr117597167475971849E0815347
chr117597790775978021E08111580
chr117597811275978277E08111785
chr117597832375978399E08111996
chr117597841575978480E08112088
chr117597858075979071E08112253
chr117597913075979305E08112803
chr117601362176013761E08147294
chr117595409675954177E082-12150








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr117591832175923153E067-43174
chr117594467275948738E067-17589
chr117591832175923153E068-43174
chr117594467275948738E068-17589
chr117591832175923153E069-43174
chr117594467275948738E069-17589
chr117594467275948738E070-17589
chr117591832175923153E071-43174
chr117594467275948738E071-17589
chr117591832175923153E072-43174
chr117594467275948738E072-17589
chr117591832175923153E073-43174
chr117594467275948738E073-17589
chr117591832175923153E074-43174
chr117594467275948738E074-17589
chr117594467275948738E081-17589
chr117591832175923153E082-43174
chr117594467275948738E082-17589