rs10900866

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0111 (3354/29980,GnomAD)
C=0122 (3558/29118,TOPMED)
C=0172 (860/5008,1000G)
C=0069 (267/3854,ALSPAC)
C=0076 (280/3708,TWINSUK)
chr5:98751615 (GRCh38.p7) (5q15)
AD
GWASdb2
1   publication(s)
See rs on genome
124 Enhancers around
30 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.98751615T>C
GRCh37.p13 chr 5NC_000005.9:g.98087319T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.796C=0.204
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.824C=0.176
1000GenomesEuropeSub1006T=0.921C=0.079
1000GenomesGlobalStudy-wide5008T=0.828C=0.172
1000GenomesSouth AsianSub978T=0.730C=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.931C=0.069
The Genome Aggregation DatabaseAfricanSub8720T=0.838C=0.162
The Genome Aggregation DatabaseAmericanSub838T=0.870C=0.130
The Genome Aggregation DatabaseEast AsianSub1616T=0.827C=0.173
The Genome Aggregation DatabaseEuropeSub18504T=0.917C=0.082
The Genome Aggregation DatabaseGlobalStudy-wide29980T=0.888C=0.111
The Genome Aggregation DatabaseOtherSub302T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.877C=0.122
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.924C=0.076
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs109008668.51E-05alcohol dependence19581569

eQTL of rs10900866 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10900866 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr59811897198119077E06731652
chr59811910998119203E06731790
chr59812008798120424E06732768
chr59812073898120826E06733419
chr59812085198120901E06733532
chr59812110298121166E06733783
chr59812119498121305E06733875
chr59812196998122627E06734650
chr59812263898122846E06735319
chr59812290598122968E06735586
chr59812303498123165E06735715
chr59812320398123356E06735884
chr59811823298118342E06830913
chr59811845198118510E06831132
chr59811870698118775E06831387
chr59811897198119077E06831652
chr59811910998119203E06831790
chr59812008798120424E06832768
chr59812073898120826E06833419
chr59812085198120901E06833532
chr59812110298121166E06833783
chr59812119498121305E06833875
chr59812196998122627E06834650
chr59812263898122846E06835319
chr59812290598122968E06835586
chr59812303498123165E06835715
chr59812320398123356E06835884
chr59812353798123602E06836218
chr59812499498125089E06837675
chr59812573898125841E06838419
chr59812671698127485E06839397
chr59811897198119077E06931652
chr59811910998119203E06931790
chr59812008798120424E06932768
chr59812073898120826E06933419
chr59812085198120901E06933532
chr59812110298121166E06933783
chr59812119498121305E06933875
chr59811870698118775E07031387
chr59811897198119077E07031652
chr59811910998119203E07031790
chr59812008798120424E07032768
chr59812073898120826E07033419
chr59812085198120901E07033532
chr59812110298121166E07033783
chr59812119498121305E07033875
chr59812196998122627E07034650
chr59812263898122846E07035319
chr59812290598122968E07035586
chr59812303498123165E07035715
chr59812320398123356E07035884
chr59812353798123602E07036218
chr59811823298118342E07130913
chr59811845198118510E07131132
chr59811870698118775E07131387
chr59811897198119077E07131652
chr59811910998119203E07131790
chr59812008798120424E07132768
chr59812073898120826E07133419
chr59812085198120901E07133532
chr59812110298121166E07133783
chr59812119498121305E07133875
chr59812196998122627E07134650
chr59812263898122846E07135319
chr59812290598122968E07135586
chr59812303498123165E07135715
chr59812320398123356E07135884
chr59811823298118342E07230913
chr59811845198118510E07231132
chr59811870698118775E07231387
chr59811897198119077E07231652
chr59811910998119203E07231790
chr59812008798120424E07232768
chr59812073898120826E07233419
chr59812085198120901E07233532
chr59812110298121166E07233783
chr59812119498121305E07233875
chr59812196998122627E07234650
chr59811650598116555E07329186
chr59811768998117990E07330370
chr59811823298118342E07330913
chr59812008798120424E07332768
chr59812073898120826E07333419
chr59812085198120901E07333532
chr59812110298121166E07333783
chr59812119498121305E07333875
chr59812196998122627E07334650
chr59812263898122846E07335319
chr59812290598122968E07335586
chr59811823298118342E07430913
chr59811845198118510E07431132
chr59811870698118775E07431387
chr59811897198119077E07431652
chr59811910998119203E07431790
chr59812008798120424E07432768
chr59812073898120826E07433419
chr59812085198120901E07433532
chr59812110298121166E07433783
chr59812119498121305E07433875
chr59812196998122627E07434650
chr59812263898122846E07435319
chr59812290598122968E07435586
chr59812303498123165E07435715
chr59812320398123356E07435884
chr59812353798123602E07436218
chr59811300198113321E08125682
chr59812073898120826E08133419
chr59812085198120901E08133532
chr59812110298121166E08133783
chr59812119498121305E08133875
chr59812196998122627E08134650
chr59812263898122846E08135319
chr59812290598122968E08135586
chr59812303498123165E08135715
chr59812320398123356E08135884
chr59812353798123602E08136218
chr59811300198113321E08225682
chr59812008798120424E08232768
chr59812073898120826E08233419
chr59812085198120901E08233532
chr59812110298121166E08233783
chr59812119498121305E08233875
chr59812196998122627E08234650
chr59812303498123165E08235715










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr59810326298107655E06715943
chr59810795698110837E06720637
chr59811086898111003E06723549
chr59810326298107655E06815943
chr59810795698110837E06820637
chr59811086898111003E06823549
chr59810326298107655E06915943
chr59810795698110837E06920637
chr59811086898111003E06923549
chr59810326298107655E07015943
chr59810795698110837E07020637
chr59811086898111003E07023549
chr59810326298107655E07115943
chr59810795698110837E07120637
chr59811086898111003E07123549
chr59810326298107655E07215943
chr59810795698110837E07220637
chr59811086898111003E07223549
chr59810326298107655E07315943
chr59810795698110837E07320637
chr59811086898111003E07323549
chr59810326298107655E07415943
chr59810795698110837E07420637
chr59811086898111003E07423549
chr59810326298107655E08115943
chr59810795698110837E08120637
chr59811086898111003E08123549
chr59810326298107655E08215943
chr59810795698110837E08220637
chr59811086898111003E08223549