rs10908907

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0385 (11538/29908,GnomAD)
A=0465 (13539/29118,TOPMED)
G==0462 (2314/5008,1000G)
A=0270 (1039/3854,ALSPAC)
A=0273 (1011/3708,TWINSUK)
chr9:89634669 (GRCh38.p7) (9q22.2)
AD
GWASdb2 | GWASCatalog
2   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.89634669G>A
GRCh37.p13 chr 9NC_000009.11:g.92249584G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.320A=0.680
1000GenomesAmericanSub694G=0.460A=0.540
1000GenomesEast AsianSub1008G=0.490A=0.510
1000GenomesEuropeSub1006G=0.723A=0.277
1000GenomesGlobalStudy-wide5008G=0.462A=0.538
1000GenomesSouth AsianSub978G=0.360A=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.730A=0.270
The Genome Aggregation DatabaseAfricanSub8698G=0.387A=0.613
The Genome Aggregation DatabaseAmericanSub834G=0.430A=0.570
The Genome Aggregation DatabaseEast AsianSub1614G=0.448A=0.552
The Genome Aggregation DatabaseEuropeSub18462G=0.744A=0.255
The Genome Aggregation DatabaseGlobalStudy-wide29908G=0.614A=0.385
The Genome Aggregation DatabaseOtherSub300G=0.600A=0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.535A=0.465
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.727A=0.273
PMID Title Author Journal
23543094Testing for associations between loci and environmental gradients using latent factor mixed models.Frichot EMol Biol Evol
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs109089070.000006alcoholism (heaviness of drinking)21529783
rs109089076.00E-06alcohol dependence21529783

eQTL of rs10908907 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10908907 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr99222270892222793E067-26791
chr99223712892237294E067-12290
chr99223730892237405E067-12179
chr99223751692237566E067-12018
chr99223799392238086E067-11498
chr99223813192239305E067-10279
chr99224981392250610E067229
chr99225061492250705E0671030
chr99225076092251158E0671176
chr99225482292254917E0675238
chr99225493492255126E0675350
chr99225518192255240E0675597
chr99225524292255709E0675658
chr99227465892274702E06725074
chr99227479092274904E06725206
chr99227500992275116E06725425
chr99227586192275932E06726277
chr99227594292275996E06726358
chr99227611192276255E06726527
chr99228962792291919E06740043
chr99229201292292308E06742428
chr99222673892226798E068-22786
chr99223488592234944E068-14640
chr99223569492235744E068-13840
chr99223606592236111E068-13473
chr99223663992236741E068-12843
chr99223712892237294E068-12290
chr99223730892237405E068-12179
chr99223751692237566E068-12018
chr99223799392238086E068-11498
chr99223813192239305E068-10279
chr99223958892239751E068-9833
chr99225397892254236E0684394
chr99225427692254796E0684692
chr99225482292254917E0685238
chr99225493492255126E0685350
chr99225518192255240E0685597
chr99227305892273170E06823474
chr99227321292273338E06823628
chr99227346992273616E06823885
chr99227393592274134E06824351
chr99227611192276255E06826527
chr99228962792291919E06840043
chr99229201292292308E06842428
chr99229233392293865E06842749
chr99229386792293940E06844283
chr99229394292294297E06844358
chr99223663992236741E069-12843
chr99223712892237294E069-12290
chr99223730892237405E069-12179
chr99223751692237566E069-12018
chr99223799392238086E069-11498
chr99223813192239305E069-10279
chr99223958892239751E069-9833
chr99225397892254236E0694394
chr99225427692254796E0694692
chr99225482292254917E0695238
chr99225493492255126E0695350
chr99225518192255240E0695597
chr99225524292255709E0695658
chr99226960192269659E06920017
chr99226970692269878E06920122
chr99226988292269947E06920298
chr99227006092271251E06920476
chr99227465892274702E06925074
chr99227611192276255E06926527
chr99228962792291919E06940043
chr99229201292292308E06942428
chr99229233392293865E06942749
chr99229386792293940E06944283
chr99221638092216445E070-33139
chr99221648192216536E070-33048
chr99221655192216612E070-32972
chr99221676192216964E070-32620
chr99221698692217040E070-32544
chr99221708292217136E070-32448
chr99221720692217404E070-32180
chr99221743192217483E070-32101
chr99222348292223934E070-25650
chr99222395992224097E070-25487
chr99222436692224420E070-25164
chr99222454792224617E070-24967
chr99222470392224760E070-24824
chr99222478692224898E070-24686
chr99223405192234322E070-15262
chr99223663992236741E070-12843
chr99223712892237294E070-12290
chr99223799392238086E070-11498
chr99223813192239305E070-10279
chr99223958892239751E070-9833
chr99224033592240421E070-9163
chr99224045992240517E070-9067
chr99224072392240900E070-8684
chr99225061492250705E0701030
chr99225076092251158E0701176
chr99225397892254236E0704394
chr99225427692254796E0704692
chr99225482292254917E0705238
chr99225493492255126E0705350
chr99225518192255240E0705597
chr99225524292255709E0705658
chr99226970692269878E07020122
chr99226988292269947E07020298
chr99227006092271251E07020476
chr99227321292273338E07023628
chr99227346992273616E07023885
chr99227523992275417E07025655
chr99227546792275567E07025883
chr99227562592275675E07026041
chr99227578092275852E07026196
chr99227586192275932E07026277
chr99227594292275996E07026358
chr99227611192276255E07026527
chr99227754692278410E07027962
chr99227845292278822E07028868
chr99227885292278906E07029268
chr99227892792279107E07029343
chr99228267492283994E07033090
chr99228943092289480E07039846
chr99228949892289552E07039914
chr99228962792291919E07040043
chr99229201292292308E07042428
chr99229233392293865E07042749
chr99229386792293940E07044283
chr99229394292294297E07044358
chr99229437992294515E07044795
chr99229456192294809E07044977
chr99229489992295005E07045315
chr99229871692298803E07049132
chr99229883992299014E07049255
chr99222625392226559E071-23025
chr99223712892237294E071-12290
chr99223730892237405E071-12179
chr99223751692237566E071-12018
chr99223799392238086E071-11498
chr99223813192239305E071-10279
chr99225381192253916E0714227
chr99225397892254236E0714394
chr99225427692254796E0714692
chr99225482292254917E0715238
chr99225493492255126E0715350
chr99225518192255240E0715597
chr99225524292255709E0715658
chr99226970692269878E07120122
chr99226988292269947E07120298
chr99227479092274904E07125206
chr99227500992275116E07125425
chr99227523992275417E07125655
chr99227546792275567E07125883
chr99227562592275675E07126041
chr99227578092275852E07126196
chr99227586192275932E07126277
chr99227594292275996E07126358
chr99227611192276255E07126527
chr99228962792291919E07140043
chr99229201292292308E07142428
chr99229233392293865E07142749
chr99229386792293940E07144283
chr99229394292294297E07144358
chr99223488592234944E072-14640
chr99223606592236111E072-13473
chr99223663992236741E072-12843
chr99223712892237294E072-12290
chr99223730892237405E072-12179
chr99223751692237566E072-12018
chr99223799392238086E072-11498
chr99223813192239305E072-10279
chr99224981392250610E072229
chr99225061492250705E0721030
chr99225342492253651E0723840
chr99225381192253916E0724227
chr99225397892254236E0724394
chr99225427692254796E0724692
chr99225482292254917E0725238
chr99225493492255126E0725350
chr99225518192255240E0725597
chr99225524292255709E0725658
chr99228962792291919E07240043
chr99229201292292308E07242428
chr99229233392293865E07242749
chr99229386792293940E07244283
chr99223488592234944E073-14640
chr99223501492235094E073-14490
chr99223536192235411E073-14173
chr99223548092235546E073-14038
chr99223569492235744E073-13840
chr99223606592236111E073-13473
chr99223663992236741E073-12843
chr99223712892237294E073-12290
chr99223730892237405E073-12179
chr99223751692237566E073-12018
chr99223799392238086E073-11498
chr99223813192239305E073-10279
chr99223958892239751E073-9833
chr99225342492253651E0733840
chr99225381192253916E0734227
chr99225397892254236E0734394
chr99225427692254796E0734692
chr99225482292254917E0735238
chr99225493492255126E0735350
chr99225518192255240E0735597
chr99225524292255709E0735658
chr99225604692256107E0736462
chr99225618392256233E0736599
chr99227125292271387E07321668
chr99227139192271486E07321807
chr99227546792275567E07325883
chr99227562592275675E07326041
chr99227578092275852E07326196
chr99227586192275932E07326277
chr99227594292275996E07326358
chr99227754692278410E07327962
chr99229201292292308E07342428
chr99229233392293865E07342749
chr99223488592234944E074-14640
chr99223606592236111E074-13473
chr99223663992236741E074-12843
chr99223712892237294E074-12290
chr99223730892237405E074-12179
chr99223751692237566E074-12018
chr99223799392238086E074-11498
chr99223813192239305E074-10279
chr99223958892239751E074-9833
chr99225307192253399E0743487
chr99225342492253651E0743840
chr99225381192253916E0744227
chr99225397892254236E0744394
chr99225427692254796E0744692
chr99225482292254917E0745238
chr99225493492255126E0745350
chr99225518192255240E0745597
chr99225524292255709E0745658
chr99225604692256107E0746462
chr99225618392256233E0746599
chr99226960192269659E07420017
chr99226970692269878E07420122
chr99226988292269947E07420298
chr99227586192275932E07426277
chr99227594292275996E07426358
chr99227611192276255E07426527
chr99228943092289480E07439846
chr99228949892289552E07439914
chr99228962792291919E07440043
chr99229201292292308E07442428
chr99229233392293865E07442749
chr99229386792293940E07444283
chr99229394292294297E07444358
chr99222320192223418E081-26166
chr99222348292223934E081-25650
chr99222395992224097E081-25487
chr99222436692224420E081-25164
chr99222454792224617E081-24967
chr99222470392224760E081-24824
chr99222478692224898E081-24686
chr99222511592225165E081-24419
chr99222530092225448E081-24136
chr99222553792225644E081-23940
chr99223799392238086E081-11498
chr99223813192239305E081-10279
chr99223958892239751E081-9833
chr99224033592240421E081-9163
chr99224045992240517E081-9067
chr99224072392240900E081-8684
chr99224121292241477E081-8107
chr99224151692241683E081-7901
chr99224488392245035E081-4549
chr99224513492245304E081-4280
chr99225381192253916E0814227
chr99225397892254236E0814394
chr99225427692254796E0814692
chr99225482292254917E0815238
chr99225493492255126E0815350
chr99225518192255240E0815597
chr99225524292255709E0815658
chr99225604692256107E0816462
chr99225618392256233E0816599
chr99225655092256731E0816966
chr99225683892256888E0817254
chr99225694192257256E0817357
chr99225741592257469E0817831
chr99225751392258073E0817929
chr99225811492258285E0818530
chr99225831992258373E0818735
chr99226151192261838E08111927
chr99226196092262010E08112376
chr99226220292262252E08112618
chr99226242392262627E08112839
chr99226277392262906E08113189
chr99227523992275417E08125655
chr99227546792275567E08125883
chr99227562592275675E08126041
chr99227578092275852E08126196
chr99227586192275932E08126277
chr99227594292275996E08126358
chr99227611192276255E08126527
chr99227754692278410E08127962
chr99228962792291919E08140043
chr99229201292292308E08142428
chr99229233392293865E08142749
chr99229386792293940E08144283
chr99229394292294297E08144358
chr99229871692298803E08149132
chr99229883992299014E08149255
chr99222436692224420E082-25164
chr99222454792224617E082-24967
chr99222470392224760E082-24824
chr99222478692224898E082-24686
chr99222511592225165E082-24419
chr99223813192239305E082-10279
chr99223958892239751E082-9833
chr99225427692254796E0824692
chr99226151192261838E08211927
chr99226196092262010E08212376
chr99226220292262252E08212618
chr99226242392262627E08212839
chr99227611192276255E08226527
chr99227754692278410E08227962
chr99228962792291919E08240043
chr99229201292292308E08242428
chr99229233392293865E08242749
chr99229386792293940E08244283
chr99229394292294297E08244358
chr99229437992294515E08244795
chr99229871692298803E08249132
chr99229883992299014E08249255










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr99221781792222620E067-26964
chr99221781792222620E068-26964
chr99221781792222620E069-26964
chr99221781792222620E070-26964
chr99221781792222620E071-26964
chr99221781792222620E072-26964
chr99221781792222620E073-26964
chr99221781792222620E074-26964
chr99221781792222620E081-26964
chr99221781792222620E082-26964