rs10923556

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0414 (12330/29778,GnomAD)
T=0376 (10950/29118,TOPMED)
T=0324 (1624/5008,1000G)
T=0481 (1853/3854,ALSPAC)
T=0487 (1806/3708,TWINSUK)
chr1:118360573 (GRCh38.p7) (1p12)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.118360573C>T
GRCh37.p13 chr 1NC_000001.10:g.118903196C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.750T=0.250
1000GenomesAmericanSub694C=0.730T=0.270
1000GenomesEast AsianSub1008C=0.652T=0.348
1000GenomesEuropeSub1006C=0.557T=0.443
1000GenomesGlobalStudy-wide5008C=0.676T=0.324
1000GenomesSouth AsianSub978C=0.680T=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.519T=0.481
The Genome Aggregation DatabaseAfricanSub8694C=0.719T=0.281
The Genome Aggregation DatabaseAmericanSub834C=0.740T=0.260
The Genome Aggregation DatabaseEast AsianSub1570C=0.632T=0.368
The Genome Aggregation DatabaseEuropeSub18378C=0.513T=0.486
The Genome Aggregation DatabaseGlobalStudy-wide29778C=0.585T=0.414
The Genome Aggregation DatabaseOtherSub302C=0.530T=0.470
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.623T=0.376
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.513T=0.487
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs109235568.77E-05alcohol dependence21703634

eQTL of rs10923556 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10923556 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1118876584118876811E082-26385
chr1118881430118881685E082-21511
chr1118881689118881885E082-21311
chr1118882125118882365E082-20831