SNP Detail Info-rs10926254

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

FMN2 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0421 (12611/29940,GnomAD)
A==0480 (13996/29116,TOPMED)
A==0475 (2379/5008,1000G)
A==0307 (1182/3854,ALSPAC)
A==0310 (1149/3708,TWINSUK)

Position: chr1:240435799 (GRCh38.p7) (1q43)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
FMN2 transcript variant 1	NM_001305424.1:c.	N/A	Intron Variant
FMN2 transcript variant 2	NM_020066.4:c.	N/A	Intron Variant
FMN2 transcript variant X4	XM_017001839.1:c.	N/A	Intron Variant
FMN2 transcript variant X5	XM_017001840.1:c.	N/A	Intron Variant
FMN2 transcript variant X6	XM_017001841.1:c.	N/A	Intron Variant
FMN2 transcript variant X7	XM_017001842.1:c.	N/A	Intron Variant
FMN2 transcript variant X8	XM_017001843.1:c.	N/A	Intron Variant
FMN2 transcript variant X3	XM_011544237.2:c.	N/A	Genic Downstream Transcript Variant
FMN2 transcript variant X1	XM_017001837.1:c.	N/A	Genic Downstream Transcript Variant
FMN2 transcript variant X2	XM_017001838.1:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.703	G=0.297
1000Genomes	American	Sub	694	A=0.420	G=0.580
1000Genomes	East Asian	Sub	1008	A=0.268	G=0.732
1000Genomes	Europe	Sub	1006	A=0.323	G=0.677
1000Genomes	Global	Study-wide	5008	A=0.475	G=0.525
1000Genomes	South Asian	Sub	978	A=0.570	G=0.430
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.307	G=0.693
The Genome Aggregation Database	African	Sub	8704	A=0.650	G=0.350
The Genome Aggregation Database	American	Sub	838	A=0.430	G=0.570
The Genome Aggregation Database	East Asian	Sub	1618	A=0.271	G=0.729
The Genome Aggregation Database	Europe	Sub	18478	A=0.329	G=0.671
The Genome Aggregation Database	Global	Study-wide	29940	A=0.421	G=0.578
The Genome Aggregation Database	Other	Sub	302	A=0.250	G=0.750
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.480	G=0.519
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.310	G=0.690

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10926254	0.00063	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	240565112	240565344	E081	-33755
chr1	240572236	240572315	E081	-26784
chr1	240628443	240628634	E081	29344
chr1	240628844	240629028	E081	29745
chr1	240565735	240565923	E082	-33176

rs10926254