rs10926828

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0367 (11001/29934,GnomAD)
C=0276 (8056/29116,TOPMED)
C=0322 (1615/5008,1000G)
C=0487 (1877/3854,ALSPAC)
C=0487 (1806/3708,TWINSUK)
chr1:242710293 (GRCh38.p7) (1q43)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
13 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.242710293T>C
GRCh37.p13 chr 1NC_000001.10:g.242873595T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.965C=0.035
1000GenomesAmericanSub694T=0.680C=0.320
1000GenomesEast AsianSub1008T=0.490C=0.510
1000GenomesEuropeSub1006T=0.564C=0.436
1000GenomesGlobalStudy-wide5008T=0.678C=0.322
1000GenomesSouth AsianSub978T=0.600C=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.513C=0.487
The Genome Aggregation DatabaseAfricanSub8712T=0.892C=0.108
The Genome Aggregation DatabaseAmericanSub830T=0.670C=0.330
The Genome Aggregation DatabaseEast AsianSub1618T=0.465C=0.535
The Genome Aggregation DatabaseEuropeSub18472T=0.522C=0.478
The Genome Aggregation DatabaseGlobalStudy-wide29934T=0.632C=0.367
The Genome Aggregation DatabaseOtherSub302T=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.723C=0.276
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.513C=0.487
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs109268282.3E-05alcohol consumption (maxi-drinks)24277619

eQTL of rs10926828 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10926828 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1242836626242836714E067-36881
chr1242855104242855216E067-18379
chr1242855104242855216E069-18379
chr1242855104242855216E070-18379
chr1242836626242836714E071-36881
chr1242837029242837204E071-36391
chr1242886467242886721E07112872
chr1242890486242890602E07116891
chr1242836626242836714E072-36881
chr1242837029242837204E072-36391
chr1242855104242855216E072-18379
chr1242886467242886721E07212872
chr1242836626242836714E074-36881
chr1242838422242838506E074-35089
chr1242886467242886721E07412872






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1242854306242854725E067-18870
chr1242854939242855018E067-18577
chr1242854306242854725E068-18870
chr1242854939242855018E068-18577
chr1242854306242854725E069-18870
chr1242854939242855018E069-18577
chr1242854306242854725E071-18870
chr1242854939242855018E071-18577
chr1242854306242854725E072-18870
chr1242854939242855018E072-18577
chr1242854306242854725E073-18870
chr1242854306242854725E074-18870
chr1242854939242855018E074-18577