rs1092985

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0155 (4640/29942,GnomAD)
C==0129 (3761/29118,TOPMED)
C==0212 (1063/5008,1000G)
C==0146 (564/3854,ALSPAC)
C==0150 (558/3708,TWINSUK)
chr5:5115396 (GRCh38.p7) (5p15.32)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
24 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.5115396C>T
GRCh37.p13 chr 5NC_000005.9:g.5115509C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.067T=0.933
1000GenomesAmericanSub694C=0.180T=0.820
1000GenomesEast AsianSub1008C=0.567T=0.433
1000GenomesEuropeSub1006C=0.157T=0.843
1000GenomesGlobalStudy-wide5008C=0.212T=0.788
1000GenomesSouth AsianSub978C=0.120T=0.880
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.146T=0.854
The Genome Aggregation DatabaseAfricanSub8716C=0.098T=0.902
The Genome Aggregation DatabaseAmericanSub838C=0.240T=0.760
The Genome Aggregation DatabaseEast AsianSub1614C=0.527T=0.473
The Genome Aggregation DatabaseEuropeSub18472C=0.144T=0.855
The Genome Aggregation DatabaseGlobalStudy-wide29942C=0.155T=0.845
The Genome Aggregation DatabaseOtherSub302C=0.220T=0.780
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.129T=0.870
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.150T=0.850
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs10929850.000107alcohol consumption23743675

eQTL of rs1092985 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1092985 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr550698085070099E067-45410
chr550698085070099E068-45410
chr550698085070099E069-45410
chr550675295067628E081-47881
chr550676515067742E081-47767
chr550677565067809E081-47700
chr551423025142348E08226793
chr551423585142522E08226849





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr551397345141096E06724225
chr551411475141237E06725638
chr551412925141449E06725783
chr551414815141534E06725972
chr551397345141096E06824225
chr551411475141237E06825638
chr551412925141449E06825783
chr551414815141534E06825972
chr551394135139564E06923904
chr551397345141096E06924225
chr551411475141237E06925638
chr551412925141449E06925783
chr551397345141096E07124225
chr551412925141449E07125783
chr551414815141534E07125972
chr551397345141096E07224225
chr551411475141237E07225638
chr551412925141449E07225783
chr551397345141096E07324225
chr551411475141237E07425638
chr551412925141449E07425783
chr551412925141449E08125783
chr551414815141534E08125972
chr551397345141096E08224225