rs10929935

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0325 (9719/29880,GnomAD)
C=0285 (8303/29118,TOPMED)
C=0348 (1742/5008,1000G)
C=0372 (1433/3854,ALSPAC)
C=0369 (1368/3708,TWINSUK)
chr2:149036100 (GRCh38.p7) (2q23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
110 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.149036100T>C
GRCh37.p13 chr 2NC_000002.11:g.149892614T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.874C=0.126
1000GenomesAmericanSub694T=0.660C=0.340
1000GenomesEast AsianSub1008T=0.318C=0.682
1000GenomesEuropeSub1006T=0.647C=0.353
1000GenomesGlobalStudy-wide5008T=0.652C=0.348
1000GenomesSouth AsianSub978T=0.700C=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.628C=0.372
The Genome Aggregation DatabaseAfricanSub8704T=0.827C=0.173
The Genome Aggregation DatabaseAmericanSub832T=0.630C=0.370
The Genome Aggregation DatabaseEast AsianSub1614T=0.295C=0.705
The Genome Aggregation DatabaseEuropeSub18428T=0.638C=0.361
The Genome Aggregation DatabaseGlobalStudy-wide29880T=0.674C=0.325
The Genome Aggregation DatabaseOtherSub302T=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.714C=0.285
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.631C=0.369
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109299350.0000726alcoholismpha002893
rs109299350.000073alcohol dependence20201924
rs109299350.00063alcohol dependence(early age of onset)20201924

eQTL of rs10929935 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10929935 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2149846322149846408E067-46206
chr2149846459149846723E067-45891
chr2149854829149854927E067-37687
chr2149855158149855224E067-37390
chr2149855279149855333E067-37281
chr2149855461149855550E067-37064
chr2149855746149855800E067-36814
chr2149855877149856491E067-36123
chr2149856612149856662E067-35952
chr2149856819149856947E067-35667
chr2149873784149874238E067-18376
chr2149854829149854927E068-37687
chr2149855158149855224E068-37390
chr2149855279149855333E068-37281
chr2149855461149855550E068-37064
chr2149855746149855800E068-36814
chr2149855877149856491E068-36123
chr2149856612149856662E068-35952
chr2149856819149856947E068-35667
chr2149857160149857268E068-35346
chr2149873784149874238E068-18376
chr2149854829149854927E069-37687
chr2149855158149855224E069-37390
chr2149855877149856491E069-36123
chr2149856612149856662E069-35952
chr2149856819149856947E069-35667
chr2149857160149857268E069-35346
chr2149858124149858274E069-34340
chr2149859275149859325E069-33289
chr2149873784149874238E069-18376
chr2149874326149874761E069-17853
chr2149855158149855224E070-37390
chr2149855279149855333E070-37281
chr2149855461149855550E070-37064
chr2149855746149855800E070-36814
chr2149855877149856491E070-36123
chr2149884133149884705E070-7909
chr2149884750149884924E070-7690
chr2149847685149847747E071-44867
chr2149854829149854927E071-37687
chr2149855158149855224E071-37390
chr2149855279149855333E071-37281
chr2149855461149855550E071-37064
chr2149855746149855800E071-36814
chr2149855877149856491E071-36123
chr2149856612149856662E071-35952
chr2149856819149856947E071-35667
chr2149857160149857268E071-35346
chr2149858124149858274E071-34340
chr2149873784149874238E071-18376
chr2149878345149878523E071-14091
chr2149846322149846408E072-46206
chr2149846459149846723E072-45891
chr2149854829149854927E072-37687
chr2149855158149855224E072-37390
chr2149855279149855333E072-37281
chr2149855461149855550E072-37064
chr2149855746149855800E072-36814
chr2149855877149856491E072-36123
chr2149856612149856662E072-35952
chr2149856819149856947E072-35667
chr2149857160149857268E072-35346
chr2149858124149858274E072-34340
chr2149859275149859325E072-33289
chr2149873784149874238E072-18376
chr2149846322149846408E073-46206
chr2149846459149846723E073-45891
chr2149854829149854927E073-37687
chr2149855158149855224E073-37390
chr2149855279149855333E073-37281
chr2149855461149855550E073-37064
chr2149855746149855800E073-36814
chr2149855877149856491E073-36123
chr2149856612149856662E073-35952
chr2149856819149856947E073-35667
chr2149858124149858274E073-34340
chr2149859275149859325E073-33289
chr2149862077149862614E073-30000
chr2149873784149874238E073-18376
chr2149846322149846408E074-46206
chr2149846459149846723E074-45891
chr2149847685149847747E074-44867
chr2149855158149855224E074-37390
chr2149855279149855333E074-37281
chr2149855461149855550E074-37064
chr2149855746149855800E074-36814
chr2149855877149856491E074-36123
chr2149856612149856662E074-35952
chr2149856819149856947E074-35667
chr2149857160149857268E074-35346
chr2149858124149858274E074-34340
chr2149878345149878523E074-14091
chr2149854829149854927E081-37687
chr2149855158149855224E081-37390
chr2149855279149855333E081-37281
chr2149855461149855550E081-37064
chr2149855746149855800E081-36814
chr2149855877149856491E081-36123
chr2149856612149856662E081-35952
chr2149856819149856947E081-35667
chr2149858124149858274E081-34340
chr2149859275149859325E081-33289
chr2149854829149854927E082-37687
chr2149855158149855224E082-37390
chr2149855279149855333E082-37281
chr2149855461149855550E082-37064
chr2149855746149855800E082-36814
chr2149855877149856491E082-36123
chr2149856612149856662E082-35952
chr2149856819149856947E082-35667










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2149895682149895807E0673068
chr2149894497149895676E0691883
chr2149895682149895807E0693068
chr2149894497149895676E0701883
chr2149895682149895807E0703068
chr2149894497149895676E0711883
chr2149894497149895676E0721883
chr2149894497149895676E0731883
chr2149894497149895676E0821883
chr2149895682149895807E0823068