rs10933849

Homo sapiens
C>T
LOC101929485 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0241 (7240/29946,GnomAD)
C==0293 (8538/29118,TOPMED)
C==0348 (1745/5008,1000G)
C==0169 (652/3854,ALSPAC)
C==0169 (626/3708,TWINSUK)
chr3:106420954 (GRCh38.p7) (3q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
62 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.106420954C>T
GRCh37.p13 chr 3NC_000003.11:g.106139801C>T

Gene: LOC101929485, uncharacterized LOC101929485(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101929485 transcriptXR_427393.3:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.439T=0.561
1000GenomesAmericanSub694C=0.390T=0.610
1000GenomesEast AsianSub1008C=0.405T=0.595
1000GenomesEuropeSub1006C=0.164T=0.836
1000GenomesGlobalStudy-wide5008C=0.348T=0.652
1000GenomesSouth AsianSub978C=0.330T=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.169T=0.831
The Genome Aggregation DatabaseAfricanSub8716C=0.399T=0.601
The Genome Aggregation DatabaseAmericanSub838C=0.410T=0.590
The Genome Aggregation DatabaseEast AsianSub1608C=0.379T=0.621
The Genome Aggregation DatabaseEuropeSub18482C=0.149T=0.851
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.241T=0.758
The Genome Aggregation DatabaseOtherSub302C=0.180T=0.820
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.293T=0.706
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.169T=0.831
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs109338490.000587alcohol consumption (maxi-drinks)24277619

eQTL of rs10933849 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10933849 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3106117812106118046E067-21755
chr3106118096106118434E067-21367
chr3106171052106171156E06731251
chr3106171477106171551E06731676
chr3106171742106171933E06731941
chr3106117812106118046E068-21755
chr3106118096106118434E068-21367
chr3106118689106118840E068-20961
chr3106171052106171156E06831251
chr3106171477106171551E06831676
chr3106171742106171933E06831941
chr3106099233106099328E069-40473
chr3106117812106118046E069-21755
chr3106118096106118434E069-21367
chr3106118689106118840E069-20961
chr3106171052106171156E06931251
chr3106171477106171551E06931676
chr3106171742106171933E06931941
chr3106098238106098471E070-41330
chr3106100376106100520E070-39281
chr3106100542106100644E070-39157
chr3106100913106101190E070-38611
chr3106101290106101340E070-38461
chr3106104999106105208E070-34593
chr3106117812106118046E070-21755
chr3106118096106118434E070-21367
chr3106118689106118840E070-20961
chr3106119027106119099E070-20702
chr3106171052106171156E07031251
chr3106171477106171551E07031676
chr3106171742106171933E07031941
chr3106117812106118046E071-21755
chr3106118096106118434E071-21367
chr3106118689106118840E071-20961
chr3106119027106119099E071-20702
chr3106168902106168963E07129101
chr3106170226106170322E07130425
chr3106171052106171156E07131251
chr3106171477106171551E07131676
chr3106171742106171933E07131941
chr3106176195106176470E07136394
chr3106117812106118046E072-21755
chr3106118096106118434E072-21367
chr3106118689106118840E072-20961
chr3106119027106119099E072-20702
chr3106120916106121336E072-18465
chr3106171052106171156E07231251
chr3106171477106171551E07231676
chr3106171742106171933E07231941
chr3106099233106099328E074-40473
chr3106117812106118046E074-21755
chr3106118096106118434E074-21367
chr3106118689106118840E074-20961
chr3106120650106120771E074-19030
chr3106171052106171156E07431251
chr3106171477106171551E07431676
chr3106171742106171933E07431941
chr3106099233106099328E081-40473
chr3106100261106100341E081-39460
chr3106100376106100520E081-39281
chr3106099233106099328E082-40473
chr3106118096106118434E082-21367