rs10935129

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0144 (4330/29954,GnomAD)
A=0188 (5496/29118,TOPMED)
A=0185 (925/5008,1000G)
A=0128 (492/3854,ALSPAC)
A=0133 (495/3708,TWINSUK)
chr3:134750689 (GRCh38.p7) (3q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
40 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.134750689T>A
GRCh37.p13 chr 3NC_000003.11:g.134469531T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.760A=0.240
1000GenomesAmericanSub694T=0.870A=0.130
1000GenomesEast AsianSub1008T=0.963A=0.037
1000GenomesEuropeSub1006T=0.881A=0.119
1000GenomesGlobalStudy-wide5008T=0.815A=0.185
1000GenomesSouth AsianSub978T=0.630A=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.872A=0.128
The Genome Aggregation DatabaseAfricanSub8708T=0.763A=0.237
The Genome Aggregation DatabaseAmericanSub838T=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1618T=0.967A=0.033
The Genome Aggregation DatabaseEuropeSub18488T=0.888A=0.111
The Genome Aggregation DatabaseGlobalStudy-wide29954T=0.855A=0.144
The Genome Aggregation DatabaseOtherSub302T=0.820A=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.811A=0.188
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.867A=0.133
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109351290.000759alcohol dependence21314694

eQTL of rs10935129 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10935129 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3134428504134428638E068-40893
chr3134428687134428737E068-40794
chr3134428906134429152E068-40379
chr3134517322134517426E06847791
chr3134518310134518485E06848779
chr3134428504134428638E069-40893
chr3134428687134428737E069-40794
chr3134428906134429152E069-40379
chr3134429182134429299E069-40232
chr3134471213134471296E0701682
chr3134471311134471389E0701780
chr3134471723134471873E0702192
chr3134471723134471873E0722192
chr3134428906134429152E073-40379
chr3134429182134429299E073-40232
chr3134517322134517426E07347791
chr3134428504134428638E081-40893
chr3134428687134428737E081-40794
chr3134428906134429152E081-40379
chr3134479999134480148E08110468
chr3134480198134480319E08110667
chr3134517322134517426E08147791
chr3134518310134518485E08148779
chr3134479999134480148E08210468
chr3134480198134480319E08210667







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3134513691134515102E06744160
chr3134515113134515916E06745582
chr3134515976134516060E06746445
chr3134516068134516147E06746537
chr3134516264134516443E06746733
chr3134513691134515102E06844160
chr3134515113134515916E06845582
chr3134515976134516060E06846445
chr3134516068134516147E06846537
chr3134516264134516443E06846733
chr3134513691134515102E06944160
chr3134515113134515916E06945582
chr3134513691134515102E07044160
chr3134513691134515102E07144160
chr3134515113134515916E07145582
chr3134516264134516443E07146733
chr3134513691134515102E07244160
chr3134515113134515916E07245582
chr3134515976134516060E07246445
chr3134516264134516443E07246733
chr3134513691134515102E07344160
chr3134515113134515916E07345582
chr3134515976134516060E07346445
chr3134516068134516147E07346537
chr3134516264134516443E07346733
chr3134513691134515102E07444160
chr3134515113134515916E07445582
chr3134515976134516060E07446445
chr3134516068134516147E07446537
chr3134516264134516443E07446733
chr3134513691134515102E08144160
chr3134515113134515916E08145582
chr3134515976134516060E08146445
chr3134516068134516147E08146537
chr3134516264134516443E08146733
chr3134513691134515102E08244160
chr3134515113134515916E08245582
chr3134515976134516060E08246445
chr3134516068134516147E08246537
chr3134516264134516443E08246733