rs10935342

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0375 (11235/29898,GnomAD)
T==0437 (12735/29118,TOPMED)
T==0363 (1818/5008,1000G)
T==0299 (1152/3854,ALSPAC)
T==0289 (1073/3708,TWINSUK)
chr3:139686500 (GRCh38.p7) (3q23)
AD
GWASdb2
1   publication(s)
See rs on genome
88 Enhancers around
13 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.139686500T>C
GRCh37.p13 chr 3NC_000003.11:g.139405342T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.665C=0.335
1000GenomesAmericanSub694T=0.250C=0.750
1000GenomesEast AsianSub1008T=0.165C=0.835
1000GenomesEuropeSub1006T=0.314C=0.686
1000GenomesGlobalStudy-wide5008T=0.363C=0.637
1000GenomesSouth AsianSub978T=0.290C=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.299C=0.701
The Genome Aggregation DatabaseAfricanSub8692T=0.626C=0.374
The Genome Aggregation DatabaseAmericanSub834T=0.200C=0.800
The Genome Aggregation DatabaseEast AsianSub1608T=0.177C=0.823
The Genome Aggregation DatabaseEuropeSub18462T=0.284C=0.715
The Genome Aggregation DatabaseGlobalStudy-wide29898T=0.375C=0.624
The Genome Aggregation DatabaseOtherSub302T=0.300C=0.700
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.437C=0.562
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.289C=0.711
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs109353426.7E-05alcoholism (heaviness of drinking)21529783

eQTL of rs10935342 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10935342 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3139374767139375023E067-30319
chr3139394306139394467E067-10875
chr3139394737139394797E067-10545
chr3139394988139395351E067-9991
chr3139395397139395447E067-9895
chr3139395515139395565E067-9777
chr3139395633139395737E067-9605
chr3139374767139375023E068-30319
chr3139375065139375369E068-29973
chr3139394306139394467E068-10875
chr3139394737139394797E068-10545
chr3139394988139395351E068-9991
chr3139374767139375023E069-30319
chr3139375065139375369E069-29973
chr3139391822139391872E069-13470
chr3139373256139373935E070-31407
chr3139374767139375023E070-30319
chr3139375065139375369E070-29973
chr3139390375139390459E070-14883
chr3139390596139390680E070-14662
chr3139390857139390985E070-14357
chr3139391822139391872E070-13470
chr3139392758139392847E070-12495
chr3139393200139393280E070-12062
chr3139393506139393625E070-11717
chr3139393746139394072E070-11270
chr3139394306139394467E070-10875
chr3139394737139394797E070-10545
chr3139394988139395351E070-9991
chr3139407898139408288E0702556
chr3139413965139414081E0708623
chr3139414688139414777E0709346
chr3139373004139373095E071-32247
chr3139373256139373935E071-31407
chr3139374767139375023E071-30319
chr3139375065139375369E071-29973
chr3139391822139391872E071-13470
chr3139374767139375023E072-30319
chr3139375065139375369E072-29973
chr3139393746139394072E072-11270
chr3139394306139394467E072-10875
chr3139394737139394797E072-10545
chr3139394988139395351E072-9991
chr3139395397139395447E072-9895
chr3139395515139395565E072-9777
chr3139395633139395737E072-9605
chr3139394306139394467E073-10875
chr3139394737139394797E073-10545
chr3139394988139395351E073-9991
chr3139395397139395447E073-9895
chr3139395515139395565E073-9777
chr3139391822139391872E074-13470
chr3139374767139375023E081-30319
chr3139375065139375369E081-29973
chr3139393200139393280E081-12062
chr3139393506139393625E081-11717
chr3139393746139394072E081-11270
chr3139394306139394467E081-10875
chr3139394988139395351E081-9991
chr3139395397139395447E081-9895
chr3139395515139395565E081-9777
chr3139395633139395737E081-9605
chr3139413965139414081E0818623
chr3139424006139424306E08118664
chr3139424330139424892E08118988
chr3139424972139425026E08119630
chr3139426257139426645E08120915
chr3139426732139426843E08121390
chr3139426902139426992E08121560
chr3139427042139427259E08121700
chr3139427309139427446E08121967
chr3139436819139437071E08131477
chr3139437364139437574E08132022
chr3139373256139373935E082-31407
chr3139374767139375023E082-30319
chr3139375065139375369E082-29973
chr3139392758139392847E082-12495
chr3139393506139393625E082-11717
chr3139393746139394072E082-11270
chr3139394306139394467E082-10875
chr3139394737139394797E082-10545
chr3139413965139414081E0828623
chr3139414688139414777E0829346
chr3139424330139424892E08218988
chr3139424972139425026E08219630
chr3139436596139436763E08231254
chr3139436819139437071E08231477
chr3139437364139437574E08232022










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3139396121139397181E067-8161
chr3139396121139397181E068-8161
chr3139397265139397379E068-7963
chr3139396121139397181E069-8161
chr3139397265139397379E069-7963
chr3139396121139397181E070-8161
chr3139397265139397379E070-7963
chr3139396121139397181E071-8161
chr3139396121139397181E072-8161
chr3139396121139397181E073-8161
chr3139396121139397181E074-8161
chr3139396121139397181E082-8161
chr3139397265139397379E082-7963