rs10935348

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0463 (13860/29932,GnomAD)
A=0465 (13566/29118,TOPMED)
C==0436 (2185/5008,1000G)
C==0395 (1523/3854,ALSPAC)
C==0393 (1459/3708,TWINSUK)
chr3:139728658 (GRCh38.p7) (3q23)
AD
GWASdb2
1   publication(s)
See rs on genome
33 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.139728658C>A
GRCh37.p13 chr 3NC_000003.11:g.139447500C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.785A=0.215
1000GenomesAmericanSub694C=0.300A=0.700
1000GenomesEast AsianSub1008C=0.173A=0.827
1000GenomesEuropeSub1006C=0.401A=0.599
1000GenomesGlobalStudy-wide5008C=0.436A=0.564
1000GenomesSouth AsianSub978C=0.370A=0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.395A=0.605
The Genome Aggregation DatabaseAfricanSub8712C=0.734A=0.266
The Genome Aggregation DatabaseAmericanSub838C=0.260A=0.740
The Genome Aggregation DatabaseEast AsianSub1614C=0.188A=0.812
The Genome Aggregation DatabaseEuropeSub18466C=0.369A=0.630
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.463A=0.537
The Genome Aggregation DatabaseOtherSub302C=0.380A=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.534A=0.465
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.393A=0.607
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs109353482.8E-05alcoholism (heaviness of drinking)21529783

eQTL of rs10935348 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10935348 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3139493126139493954E06745626
chr3139493126139493954E06845626
chr3139492907139492967E06945407
chr3139493126139493954E06945626
chr3139407898139408288E070-39212
chr3139413965139414081E070-33419
chr3139414688139414777E070-32723
chr3139492907139492967E07045407
chr3139493126139493954E07045626
chr3139493126139493954E07145626
chr3139493126139493954E07245626
chr3139493126139493954E07445626
chr3139413965139414081E081-33419
chr3139424006139424306E081-23194
chr3139424330139424892E081-22608
chr3139424972139425026E081-22474
chr3139426257139426645E081-20855
chr3139426732139426843E081-20657
chr3139426902139426992E081-20508
chr3139427042139427259E081-20241
chr3139427309139427446E081-20054
chr3139436819139437071E081-10429
chr3139437364139437574E081-9926
chr3139492907139492967E08145407
chr3139493126139493954E08145626
chr3139413965139414081E082-33419
chr3139414688139414777E082-32723
chr3139424330139424892E082-22608
chr3139424972139425026E082-22474
chr3139436596139436763E082-10737
chr3139436819139437071E082-10429
chr3139437364139437574E082-9926
chr3139493126139493954E08245626