rs10940057

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0150 (4510/29910,GnomAD)
G=0147 (4297/29118,TOPMED)
G=0177 (887/5008,1000G)
G=0143 (552/3854,ALSPAC)
G=0139 (514/3708,TWINSUK)
chr5:66236339 (GRCh38.p7) (5q12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.66236339A>G
GRCh37.p13 chr 5NC_000005.9:g.65532167A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.840G=0.160
1000GenomesAmericanSub694A=0.880G=0.120
1000GenomesEast AsianSub1008A=0.807G=0.193
1000GenomesEuropeSub1006A=0.873G=0.127
1000GenomesGlobalStudy-wide5008A=0.823G=0.177
1000GenomesSouth AsianSub978A=0.730G=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.857G=0.143
The Genome Aggregation DatabaseAfricanSub8700A=0.839G=0.161
The Genome Aggregation DatabaseAmericanSub832A=0.860G=0.140
The Genome Aggregation DatabaseEast AsianSub1614A=0.789G=0.211
The Genome Aggregation DatabaseEuropeSub18464A=0.859G=0.141
The Genome Aggregation DatabaseGlobalStudy-wide29910A=0.849G=0.150
The Genome Aggregation DatabaseOtherSub300A=0.830G=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.852G=0.147
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.861G=0.139
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109400570.000178alcohol dependence21314694

eQTL of rs10940057 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10940057 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr56552843965529086E081-3081