rs10941189

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0287 (8582/29904,GnomAD)
A=0239 (6961/29118,TOPMED)
A=0298 (1494/5008,1000G)
A=0369 (1421/3854,ALSPAC)
A=0348 (1292/3708,TWINSUK)
chr5:34489443 (GRCh38.p7) (5p13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
178 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.34489443C>A
GRCh37.p13 chr 5NC_000005.9:g.34489548C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.890A=0.110
1000GenomesAmericanSub694C=0.740A=0.260
1000GenomesEast AsianSub1008C=0.713A=0.287
1000GenomesEuropeSub1006C=0.638A=0.362
1000GenomesGlobalStudy-wide5008C=0.702A=0.298
1000GenomesSouth AsianSub978C=0.480A=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.631A=0.369
The Genome Aggregation DatabaseAfricanSub8700C=0.871A=0.129
The Genome Aggregation DatabaseAmericanSub834C=0.730A=0.270
The Genome Aggregation DatabaseEast AsianSub1616C=0.734A=0.266
The Genome Aggregation DatabaseEuropeSub18452C=0.636A=0.363
The Genome Aggregation DatabaseGlobalStudy-wide29904C=0.713A=0.287
The Genome Aggregation DatabaseOtherSub302C=0.670A=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.760A=0.239
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.652A=0.348
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs109411890.00097alcohol consumption (maxi-drinks)24277619

eQTL of rs10941189 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10941189 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr53448345034483911E067-5637
chr53448445334484630E067-4918
chr53448482534484876E067-4672
chr53448498434485121E067-4427
chr53448569834485771E067-3777
chr53448585334485945E067-3603
chr53448599034486053E067-3495
chr53448619734486860E067-2688
chr53448687834486990E067-2558
chr53448702634487180E067-2368
chr53448726234487318E067-2230
chr53448735834487990E067-1558
chr53448819934488343E067-1205
chr53449688634497774E0677338
chr53450249734502587E06712949
chr53450270634502774E06713158
chr53450282434502886E06713276
chr53450318934503239E06713641
chr53450334634503466E06713798
chr53450356834504702E06714020
chr53448272634482787E068-6761
chr53448445334484630E068-4918
chr53448482534484876E068-4672
chr53448498434485121E068-4427
chr53448569834485771E068-3777
chr53448585334485945E068-3603
chr53448599034486053E068-3495
chr53448619734486860E068-2688
chr53448687834486990E068-2558
chr53448702634487180E068-2368
chr53448726234487318E068-2230
chr53448735834487990E068-1558
chr53449057834490872E0681030
chr53449098534491136E0681437
chr53449116534491931E0681617
chr53449637234496769E0686824
chr53449688634497774E0687338
chr53450214234502258E06812594
chr53450249734502587E06812949
chr53450270634502774E06813158
chr53450282434502886E06813276
chr53450318934503239E06813641
chr53450334634503466E06813798
chr53450565934506100E06816111
chr53452375334523889E06834205
chr53448329934483349E069-6199
chr53448569834485771E069-3777
chr53448585334485945E069-3603
chr53448599034486053E069-3495
chr53448619734486860E069-2688
chr53448687834486990E069-2558
chr53448702634487180E069-2368
chr53448726234487318E069-2230
chr53449057834490872E0691030
chr53449098534491136E0691437
chr53449116534491931E0691617
chr53449688634497774E0697338
chr53450214234502258E06912594
chr53450249734502587E06912949
chr53450270634502774E06913158
chr53450318934503239E06913641
chr53450334634503466E06913798
chr53450356834504702E06914020
chr53452285634523710E06933308
chr53452375334523889E06934205
chr53448619734486860E070-2688
chr53449116534491931E0701617
chr53450249734502587E07012949
chr53450270634502774E07013158
chr53450282434502886E07013276
chr53450318934503239E07013641
chr53450334634503466E07013798
chr53450356834504702E07014020
chr53447467834476238E071-13310
chr53448445334484630E071-4918
chr53448482534484876E071-4672
chr53448498434485121E071-4427
chr53448569834485771E071-3777
chr53448585334485945E071-3603
chr53448599034486053E071-3495
chr53448619734486860E071-2688
chr53448687834486990E071-2558
chr53448702634487180E071-2368
chr53448726234487318E071-2230
chr53448735834487990E071-1558
chr53449042234490560E071874
chr53449057834490872E0711030
chr53449098534491136E0711437
chr53449116534491931E0711617
chr53449637234496769E0716824
chr53449688634497774E0717338
chr53450214234502258E07112594
chr53450249734502587E07112949
chr53450270634502774E07113158
chr53450282434502886E07113276
chr53450318934503239E07113641
chr53450334634503466E07113798
chr53452285634523710E07133308
chr53452375334523889E07134205
chr53452419034524280E07134642
chr53448329934483349E072-6199
chr53448445334484630E072-4918
chr53448482534484876E072-4672
chr53448498434485121E072-4427
chr53448569834485771E072-3777
chr53448585334485945E072-3603
chr53448599034486053E072-3495
chr53448619734486860E072-2688
chr53448702634487180E072-2368
chr53448726234487318E072-2230
chr53448735834487990E072-1558
chr53449116534491931E0721617
chr53449688634497774E0727338
chr53450214234502258E07212594
chr53450249734502587E07212949
chr53450270634502774E07213158
chr53450282434502886E07213276
chr53450318934503239E07213641
chr53450334634503466E07213798
chr53450356834504702E07214020
chr53452285634523710E07233308
chr53448482534484876E073-4672
chr53448498434485121E073-4427
chr53448569834485771E073-3777
chr53448585334485945E073-3603
chr53448599034486053E073-3495
chr53448619734486860E073-2688
chr53448687834486990E073-2558
chr53448702634487180E073-2368
chr53449116534491931E0731617
chr53449688634497774E0737338
chr53450270634502774E07313158
chr53450282434502886E07313276
chr53450318934503239E07313641
chr53450334634503466E07313798
chr53448329934483349E074-6199
chr53448345034483911E074-5637
chr53448445334484630E074-4918
chr53448482534484876E074-4672
chr53448498434485121E074-4427
chr53448569834485771E074-3777
chr53448585334485945E074-3603
chr53448599034486053E074-3495
chr53448619734486860E074-2688
chr53448687834486990E074-2558
chr53448702634487180E074-2368
chr53448726234487318E074-2230
chr53448735834487990E074-1558
chr53449116534491931E0741617
chr53449688634497774E0747338
chr53450249734502587E07412949
chr53450270634502774E07413158
chr53450282434502886E07413276
chr53448619734486860E081-2688
chr53448687834486990E081-2558
chr53448702634487180E081-2368
chr53449116534491931E0811617
chr53449960034499708E08110052
chr53449972734499880E08110179
chr53450066834500868E08111120
chr53450106134501446E08111513
chr53450214234502258E08112594
chr53450249734502587E08112949
chr53450270634502774E08113158
chr53450282434502886E08113276
chr53450318934503239E08113641
chr53450334634503466E08113798
chr53450356834504702E08114020
chr53448619734486860E082-2688
chr53448687834486990E082-2558
chr53448702634487180E082-2368
chr53449116534491931E0821617
chr53450066834500868E08211120
chr53450270634502774E08213158
chr53450282434502886E08213276
chr53450318934503239E08213641
chr53450334634503466E08213798
chr53450356834504702E08214020