rs10953881

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0128 (3859/29952,GnomAD)
C==0179 (5226/29118,TOPMED)
C==0144 (722/5008,1000G)
C==0079 (305/3854,ALSPAC)
C==0077 (286/3708,TWINSUK)
chr7:118968071 (GRCh38.p7) (7q31.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.118968071C>T
GRCh37.p13 chr 7NC_000007.13:g.118608125C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.343T=0.657
1000GenomesAmericanSub694C=0.100T=0.900
1000GenomesEast AsianSub1008C=0.080T=0.920
1000GenomesEuropeSub1006C=0.073T=0.927
1000GenomesGlobalStudy-wide5008C=0.144T=0.856
1000GenomesSouth AsianSub978C=0.050T=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.079T=0.921
The Genome Aggregation DatabaseAfricanSub8706C=0.297T=0.703
The Genome Aggregation DatabaseAmericanSub834C=0.110T=0.890
The Genome Aggregation DatabaseEast AsianSub1612C=0.091T=0.909
The Genome Aggregation DatabaseEuropeSub18498C=0.054T=0.945
The Genome Aggregation DatabaseGlobalStudy-wide29952C=0.128T=0.871
The Genome Aggregation DatabaseOtherSub302C=0.120T=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.179T=0.820
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.077T=0.923
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs109538818.21E-07alcohol consumption22613542

eQTL of rs10953881 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10953881 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7118614632118614702E0816507
chr7118614812118615340E0816687
chr7118639808118640007E08131683
chr7118640023118640111E08131898
chr7118646613118646739E08138488
chr7118647292118647578E08139167