rs10953885

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0135 (4063/29948,GnomAD)
T==0188 (5482/29118,TOPMED)
T==0151 (757/5008,1000G)
T==0079 (305/3854,ALSPAC)
T==0077 (286/3708,TWINSUK)
chr7:118968349 (GRCh38.p7) (7q31.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.118968349T>C
GRCh37.p13 chr 7NC_000007.13:g.118608403T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.370C=0.630
1000GenomesAmericanSub694T=0.100C=0.900
1000GenomesEast AsianSub1008T=0.080C=0.920
1000GenomesEuropeSub1006T=0.073C=0.927
1000GenomesGlobalStudy-wide5008T=0.151C=0.849
1000GenomesSouth AsianSub978T=0.050C=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.079C=0.921
The Genome Aggregation DatabaseAfricanSub8710T=0.320C=0.680
The Genome Aggregation DatabaseAmericanSub836T=0.110C=0.890
The Genome Aggregation DatabaseEast AsianSub1606T=0.092C=0.908
The Genome Aggregation DatabaseEuropeSub18494T=0.054C=0.945
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.135C=0.864
The Genome Aggregation DatabaseOtherSub302T=0.120C=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.188C=0.811
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.077C=0.923
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs109538856.63E-07alcohol consumption22613542

eQTL of rs10953885 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10953885 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7118614632118614702E0816229
chr7118614812118615340E0816409
chr7118639808118640007E08131405
chr7118640023118640111E08131620
chr7118646613118646739E08138210
chr7118647292118647578E08138889