rs10969853

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0082 (2405/29118,TOPMED)
C=0085 (2211/25968,GnomAD)
C=0153 (767/5008,1000G)
C=0066 (256/3854,ALSPAC)
C=0066 (243/3708,TWINSUK)
chr9:30751222 (GRCh38.p7) (9p21.1)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.30751222T>C
GRCh37.p13 chr 9NC_000009.11:g.30751220T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.936C=0.064
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.660C=0.340
1000GenomesEuropeSub1006T=0.934C=0.066
1000GenomesGlobalStudy-wide5008T=0.847C=0.153
1000GenomesSouth AsianSub978T=0.790C=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.934C=0.066
The Genome Aggregation DatabaseAfricanSub7756T=0.911C=0.089
The Genome Aggregation DatabaseAmericanSub412T=0.930C=0.070
The Genome Aggregation DatabaseEast AsianSub1502T=0.661C=0.339
The Genome Aggregation DatabaseEuropeSub15998T=0.939C=0.060
The Genome Aggregation DatabaseGlobalStudy-wide25968T=0.914C=0.085
The Genome Aggregation DatabaseOtherSub300T=0.940C=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.917C=0.082
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.934C=0.066
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs109698535E-06alcohol dependence (age at onset)24962325

eQTL of rs10969853 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10969853 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr93071291730713640E067-37580
chr93071291730713640E068-37580
chr93071291730713640E070-37580
chr93071291730713640E071-37580
chr93071291730713640E072-37580
chr93071291730713640E074-37580