SNP Detail Info-rs1097863

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

LOC105371078 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0150 (4498/29944,GnomAD)
G=0141 (4113/29118,TOPMED)
G=0247 (1235/5008,1000G)
G=0149 (576/3854,ALSPAC)
G=0166 (617/3708,TWINSUK)

Position: chr16:10233472 (GRCh38.p7) (16p13.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 28 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 16	NC_000016.10:g.10233472T>G
GRCh37.p13 chr 16	NC_000016.9:g.10327329T>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105371078 transcript	XR_001752077.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.989	G=0.011
1000Genomes	American	Sub	694	T=0.680	G=0.320
1000Genomes	East Asian	Sub	1008	T=0.434	G=0.566
1000Genomes	Europe	Sub	1006	T=0.820	G=0.180
1000Genomes	Global	Study-wide	5008	T=0.753	G=0.247
1000Genomes	South Asian	Sub	978	T=0.750	G=0.250
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.851	G=0.149
The Genome Aggregation Database	African	Sub	8724	T=0.965	G=0.035
The Genome Aggregation Database	American	Sub	834	T=0.630	G=0.370
The Genome Aggregation Database	East Asian	Sub	1614	T=0.438	G=0.562
The Genome Aggregation Database	Europe	Sub	18470	T=0.840	G=0.159
The Genome Aggregation Database	Global	Study-wide	29944	T=0.849	G=0.150
The Genome Aggregation Database	Other	Sub	302	T=0.900	G=0.100
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.858	G=0.141
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.834	G=0.166

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs1097863	0.00032	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr16	10336001	10336233	E068	8672
chr16	10336278	10336332	E068	8949
chr16	10350635	10351340	E068	23306
chr16	10336001	10336233	E071	8672
chr16	10336278	10336332	E071	8949
chr16	10336510	10336550	E071	9181
chr16	10350635	10351340	E071	23306
chr16	10351380	10351537	E071	24051
chr16	10336001	10336233	E073	8672
chr16	10336278	10336332	E073	8949
chr16	10336510	10336550	E073	9181
chr16	10316024	10316221	E081	-11108
chr16	10316368	10316736	E081	-10593
chr16	10317643	10317786	E081	-9543
chr16	10318344	10318524	E081	-8805
chr16	10318617	10318684	E081	-8645
chr16	10318685	10319073	E081	-8256
chr16	10319128	10319364	E081	-7965
chr16	10319824	10319874	E081	-7455
chr16	10320055	10320487	E081	-6842
chr16	10320586	10320994	E081	-6335
chr16	10336001	10336233	E081	8672
chr16	10336278	10336332	E081	8949
chr16	10336510	10336550	E081	9181
chr16	10339398	10339476	E081	12069
chr16	10295144	10295427	E082	-31902
chr16	10320055	10320487	E082	-6842
chr16	10320586	10320994	E082	-6335

rs1097863