rs1097863

Homo sapiens
T>G
LOC105371078 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0150 (4498/29944,GnomAD)
G=0141 (4113/29118,TOPMED)
G=0247 (1235/5008,1000G)
G=0149 (576/3854,ALSPAC)
G=0166 (617/3708,TWINSUK)
chr16:10233472 (GRCh38.p7) (16p13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.10233472T>G
GRCh37.p13 chr 16NC_000016.9:g.10327329T>G

Gene: LOC105371078, uncharacterized LOC105371078(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105371078 transcriptXR_001752077.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.989G=0.011
1000GenomesAmericanSub694T=0.680G=0.320
1000GenomesEast AsianSub1008T=0.434G=0.566
1000GenomesEuropeSub1006T=0.820G=0.180
1000GenomesGlobalStudy-wide5008T=0.753G=0.247
1000GenomesSouth AsianSub978T=0.750G=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.851G=0.149
The Genome Aggregation DatabaseAfricanSub8724T=0.965G=0.035
The Genome Aggregation DatabaseAmericanSub834T=0.630G=0.370
The Genome Aggregation DatabaseEast AsianSub1614T=0.438G=0.562
The Genome Aggregation DatabaseEuropeSub18470T=0.840G=0.159
The Genome Aggregation DatabaseGlobalStudy-wide29944T=0.849G=0.150
The Genome Aggregation DatabaseOtherSub302T=0.900G=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.858G=0.141
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.834G=0.166
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs10978630.00032alcohol dependence20201924

eQTL of rs1097863 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1097863 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161033600110336233E0688672
chr161033627810336332E0688949
chr161035063510351340E06823306
chr161033600110336233E0718672
chr161033627810336332E0718949
chr161033651010336550E0719181
chr161035063510351340E07123306
chr161035138010351537E07124051
chr161033600110336233E0738672
chr161033627810336332E0738949
chr161033651010336550E0739181
chr161031602410316221E081-11108
chr161031636810316736E081-10593
chr161031764310317786E081-9543
chr161031834410318524E081-8805
chr161031861710318684E081-8645
chr161031868510319073E081-8256
chr161031912810319364E081-7965
chr161031982410319874E081-7455
chr161032005510320487E081-6842
chr161032058610320994E081-6335
chr161033600110336233E0818672
chr161033627810336332E0818949
chr161033651010336550E0819181
chr161033939810339476E08112069
chr161029514410295427E082-31902
chr161032005510320487E082-6842
chr161032058610320994E082-6335