SNP Detail Info-rs10980992

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.97183759C>T
GRCh37.p13 chr 9	NC_000009.11:g.99946041C>T

Molecule type	Change	Amino acid[Codon]	SO Term
ANKRD18CP transcript	NR_136286.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.889	T=0.111
1000Genomes	American	Sub	694	C=0.820	T=0.180
1000Genomes	East Asian	Sub	1008	C=0.900	T=0.100
1000Genomes	Europe	Sub	1006	C=0.815	T=0.185
1000Genomes	Global	Study-wide	5008	C=0.844	T=0.156
1000Genomes	South Asian	Sub	978	C=0.780	T=0.220
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.802	T=0.198
The Genome Aggregation Database	African	Sub	8726	C=0.873	T=0.127
The Genome Aggregation Database	American	Sub	836	C=0.800	T=0.200
The Genome Aggregation Database	East Asian	Sub	1608	C=0.923	T=0.077
The Genome Aggregation Database	Europe	Sub	18474	C=0.806	T=0.193
The Genome Aggregation Database	Global	Study-wide	29946	C=0.833	T=0.166
The Genome Aggregation Database	Other	Sub	302	C=0.890	T=0.110
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.859	T=0.140
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.800	T=0.200

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs10980992	0.000331	alcohol dependence	24277619

eQTL of rs10980992 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr9:99946041	ANKRD18CP	ENSG00000159712.10	C>T	1.1345e-14	-37476	Cerebellum
Chr9:99946041	CCDC180	ENSG00000197816.9	C>T	3.1637e-9	-62426	Cerebellum
Chr9:99946041	ANKRD18CP	ENSG00000159712.10	C>T	7.9594e-16	-37476	Frontal_Cortex_BA9
Chr9:99946041	RP11-498P14.5	ENSG00000203279.3	C>T	1.1696e-10	-54941	Frontal_Cortex_BA9
Chr9:99946041	CCDC180	ENSG00000197816.9	C>T	1.0793e-4	-62426	Cortex
Chr9:99946041	ANKRD18CP	ENSG00000159712.10	C>T	7.7011e-11	-37476	Cerebellar_Hemisphere
Chr9:99946041	RP11-498P14.5	ENSG00000203279.3	C>T	2.8676e-15	-54941	Cerebellar_Hemisphere
Chr9:99946041	CCDC180	ENSG00000197816.9	C>T	2.0973e-3	-62426	Caudate_basal_ganglia
Chr9:99946041	RP11-520B13.4	ENSG00000228376.3	C>T	4.3869e-13	101814	Anterior_cingulate_cortex
Chr9:99946041	ANKRD18CP	ENSG00000159712.10	C>T	9.3301e-10	-37476	Anterior_cingulate_cortex
Chr9:99946041	RP11-498P14.5	ENSG00000203279.3	C>T	1.3477e-12	-54941	Nucleus_accumbens_basal_ganglia

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	99912092	99912163	E068	-33878
chr9	99922747	99922856	E068	-23185
chr9	99938466	99938853	E070	-7188
chr9	99938466	99938853	E081	-7188

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr9	99982946	99983021	E067	36905
chr9	99983107	99984391	E067	37066
chr9	99984447	99984555	E067	38406
chr9	99984694	99984886	E067	38653
chr9	99982946	99983021	E068	36905
chr9	99983107	99984391	E068	37066
chr9	99984447	99984555	E068	38406
chr9	99984694	99984886	E068	38653
chr9	99983107	99984391	E069	37066
chr9	99984447	99984555	E069	38406
chr9	99984694	99984886	E069	38653
chr9	99982946	99983021	E071	36905
chr9	99983107	99984391	E071	37066
chr9	99984694	99984886	E071	38653
chr9	99982946	99983021	E072	36905
chr9	99983107	99984391	E072	37066
chr9	99984447	99984555	E072	38406
chr9	99984694	99984886	E072	38653
chr9	99982946	99983021	E073	36905
chr9	99983107	99984391	E073	37066
chr9	99984447	99984555	E073	38406
chr9	99984694	99984886	E073	38653
chr9	99983107	99984391	E074	37066
chr9	99984447	99984555	E074	38406
chr9	99983107	99984391	E082	37066
chr9	99984447	99984555	E082	38406
chr9	99984694	99984886	E082	38653

rs10980992