rs10982289

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0158 (4722/29822,GnomAD)
A=0188 (5474/29118,TOPMED)
A=0168 (840/5008,1000G)
A=0186 (717/3854,ALSPAC)
A=0184 (682/3708,TWINSUK)
chr9:114552494 (GRCh38.p7) (9q32)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.114552494G>A
GRCh37.p13 chr 9NC_000009.11:g.117314774G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.868A=0.132
1000GenomesAmericanSub694G=0.870A=0.130
1000GenomesEast AsianSub1008G=0.769A=0.231
1000GenomesEuropeSub1006G=0.836A=0.164
1000GenomesGlobalStudy-wide5008G=0.832A=0.168
1000GenomesSouth AsianSub978G=0.820A=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.814A=0.186
The Genome Aggregation DatabaseAfricanSub8608G=0.868A=0.132
The Genome Aggregation DatabaseAmericanSub832G=0.850A=0.150
The Genome Aggregation DatabaseEast AsianSub1606G=0.745A=0.255
The Genome Aggregation DatabaseEuropeSub18474G=0.837A=0.162
The Genome Aggregation DatabaseGlobalStudy-wide29822G=0.841A=0.158
The Genome Aggregation DatabaseOtherSub302G=0.830A=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.812A=0.188
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.816A=0.184
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109822890.00012alcohol dependence(Early Onset)20201924
rs109822890.00014alcohol dependence20201924

eQTL of rs10982289 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10982289 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9117352319117352376E06737545
chr9117352900117352964E06838126
chr9117269758117270527E069-44247
chr9117352319117352376E06937545
chr9117352319117352376E07137545
chr9117306625117306994E072-7780
chr9117352319117352376E07237545
chr9117352900117352964E07238126
chr9117352319117352376E07337545
chr9117357934117357984E07343160
chr9117358184117358234E07343410
chr9117352319117352376E08137545
chr9117352319117352376E08237545
chr9117352900117352964E08238126








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9117266355117268541E067-46233
chr9117349138117351931E06734364
chr9117266355117268541E068-46233
chr9117349138117351931E06834364
chr9117266355117268541E069-46233
chr9117349138117351931E06934364
chr9117266355117268541E070-46233
chr9117349138117351931E07034364
chr9117266355117268541E071-46233
chr9117349138117351931E07134364
chr9117266355117268541E072-46233
chr9117349138117351931E07234364
chr9117266355117268541E073-46233
chr9117349138117351931E07334364
chr9117266355117268541E074-46233
chr9117349138117351931E07434364
chr9117349138117351931E08134364
chr9117266355117268541E082-46233
chr9117349138117351931E08234364