rs10984229

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0220 (6587/29912,GnomAD)
C=0178 (5194/29118,TOPMED)
C=0257 (1285/5008,1000G)
C=0282 (1085/3854,ALSPAC)
C=0261 (968/3708,TWINSUK)
chr9:118797075 (GRCh38.p7) (9q33.1)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.118797075T>C
GRCh37.p13 chr 9NC_000009.11:g.121559353T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.949C=0.051
1000GenomesAmericanSub694T=0.780C=0.220
1000GenomesEast AsianSub1008T=0.529C=0.471
1000GenomesEuropeSub1006T=0.725C=0.275
1000GenomesGlobalStudy-wide5008T=0.743C=0.257
1000GenomesSouth AsianSub978T=0.680C=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.718C=0.282
The Genome Aggregation DatabaseAfricanSub8706T=0.908C=0.092
The Genome Aggregation DatabaseAmericanSub836T=0.760C=0.240
The Genome Aggregation DatabaseEast AsianSub1606T=0.535C=0.465
The Genome Aggregation DatabaseEuropeSub18464T=0.742C=0.258
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.779C=0.220
The Genome Aggregation DatabaseOtherSub300T=0.760C=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.821C=0.178
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.739C=0.261
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs109842290.000116alcohol consumption (maxi-drinks)24277619

eQTL of rs10984229 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10984229 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9121545256121545329E070-14024
chr9121545504121545632E070-13721
chr9121591717121591863E07032364
chr9121591949121592003E07032596
chr9121547471121548001E081-11352
chr9121547471121548001E082-11352