rs10988439

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0141 (4239/29968,GnomAD)
T=0158 (4608/29118,TOPMED)
T=0141 (705/5008,1000G)
T=0182 (703/3854,ALSPAC)
T=0178 (659/3708,TWINSUK)
chr9:129589940 (GRCh38.p7) (9q34.11)
AD
GWASdb2
1   publication(s)
See rs on genome
336 Enhancers around
26 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.129589940G>T
GRCh37.p13 chr 9NC_000009.11:g.132352219G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.874T=0.126
1000GenomesAmericanSub694G=0.880T=0.120
1000GenomesEast AsianSub1008G=0.953T=0.047
1000GenomesEuropeSub1006G=0.812T=0.188
1000GenomesGlobalStudy-wide5008G=0.859T=0.141
1000GenomesSouth AsianSub978G=0.780T=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.818T=0.182
The Genome Aggregation DatabaseAfricanSub8728G=0.864T=0.136
The Genome Aggregation DatabaseAmericanSub838G=0.880T=0.120
The Genome Aggregation DatabaseEast AsianSub1620G=0.949T=0.051
The Genome Aggregation DatabaseEuropeSub18484G=0.848T=0.151
The Genome Aggregation DatabaseGlobalStudy-wide29968G=0.858T=0.141
The Genome Aggregation DatabaseOtherSub298G=0.760T=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.841T=0.158
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.822T=0.178
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109884390.00014alcohol dependence20201924

eQTL of rs10988439 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10988439 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9132310274132311896E067-40323
chr9132313309132313370E067-38849
chr9132323971132324630E067-27589
chr9132324671132324755E067-27464
chr9132324826132324967E067-27252
chr9132324982132325042E067-27177
chr9132328723132328813E067-23406
chr9132329032132329177E067-23042
chr9132329207132329296E067-22923
chr9132329311132329385E067-22834
chr9132330101132333434E067-18785
chr9132364722132365659E06712503
chr9132375147132376264E06722928
chr9132376419132376507E06724200
chr9132376603132376837E06724384
chr9132386343132387040E06734124
chr9132390317132390915E06738098
chr9132390949132390997E06738730
chr9132391086132391273E06738867
chr9132391543132391626E06739324
chr9132391678132391756E06739459
chr9132391852132391935E06739633
chr9132391954132392219E06739735
chr9132392282132392440E06740063
chr9132392534132392737E06740315
chr9132392872132392932E06740653
chr9132392934132392988E06740715
chr9132392996132393103E06740777
chr9132393133132393499E06740914
chr9132394094132394253E06741875
chr9132394557132394611E06742338
chr9132394794132395092E06742575
chr9132317736132317911E068-34308
chr9132318048132318425E068-33794
chr9132323971132324630E068-27589
chr9132324826132324967E068-27252
chr9132324982132325042E068-27177
chr9132328723132328813E068-23406
chr9132329032132329177E068-23042
chr9132329207132329296E068-22923
chr9132329311132329385E068-22834
chr9132329430132329525E068-22694
chr9132329675132329871E068-22348
chr9132329875132329995E068-22224
chr9132330101132333434E068-18785
chr9132333568132334082E068-18137
chr9132364722132365659E06812503
chr9132365779132365840E06813560
chr9132365907132365951E06813688
chr9132365991132366195E06813772
chr9132376419132376507E06824200
chr9132390317132390915E06838098
chr9132390949132390997E06838730
chr9132391086132391273E06838867
chr9132392996132393103E06840777
chr9132393768132394016E06841549
chr9132394557132394611E06842338
chr9132394794132395092E06842575
chr9132401343132401534E06849124
chr9132401570132401812E06849351
chr9132401851132401918E06849632
chr9132310274132311896E069-40323
chr9132323971132324630E069-27589
chr9132324671132324755E069-27464
chr9132328584132328706E069-23513
chr9132328723132328813E069-23406
chr9132329032132329177E069-23042
chr9132329207132329296E069-22923
chr9132329311132329385E069-22834
chr9132329430132329525E069-22694
chr9132329675132329871E069-22348
chr9132329875132329995E069-22224
chr9132330101132333434E069-18785
chr9132333568132334082E069-18137
chr9132364722132365659E06912503
chr9132370506132370556E06918287
chr9132370754132370935E06918535
chr9132370953132374010E06918734
chr9132374144132374229E06921925
chr9132374286132374859E06922067
chr9132375147132376264E06922928
chr9132376419132376507E06924200
chr9132376603132376837E06924384
chr9132390317132390915E06938098
chr9132390949132390997E06938730
chr9132391086132391273E06938867
chr9132391543132391626E06939324
chr9132391678132391756E06939459
chr9132392872132392932E06940653
chr9132392934132392988E06940715
chr9132392996132393103E06940777
chr9132393133132393499E06940914
chr9132393768132394016E06941549
chr9132394094132394253E06941875
chr9132394557132394611E06942338
chr9132394794132395092E06942575
chr9132401343132401534E06949124
chr9132401570132401812E06949351
chr9132401851132401918E06949632
chr9132313309132313370E070-38849
chr9132318755132322242E070-29977
chr9132323824132323878E070-28341
chr9132323971132324630E070-27589
chr9132324671132324755E070-27464
chr9132363410132363502E07011191
chr9132364722132365659E07012503
chr9132365779132365840E07013560
chr9132365907132365951E07013688
chr9132365991132366195E07013772
chr9132366254132366365E07014035
chr9132374144132374229E07021925
chr9132374286132374859E07022067
chr9132375147132376264E07022928
chr9132390317132390915E07038098
chr9132390949132390997E07038730
chr9132393506132393698E07041287
chr9132401851132401918E07049632
chr9132310274132311896E071-40323
chr9132313309132313370E071-38849
chr9132313462132313531E071-38688
chr9132318048132318425E071-33794
chr9132318755132322242E071-29977
chr9132323971132324630E071-27589
chr9132324671132324755E071-27464
chr9132324826132324967E071-27252
chr9132324982132325042E071-27177
chr9132328584132328706E071-23513
chr9132328723132328813E071-23406
chr9132329032132329177E071-23042
chr9132329207132329296E071-22923
chr9132329311132329385E071-22834
chr9132329430132329525E071-22694
chr9132329675132329871E071-22348
chr9132329875132329995E071-22224
chr9132330101132333434E071-18785
chr9132364722132365659E07112503
chr9132368728132369123E07116509
chr9132369133132370398E07116914
chr9132375147132376264E07122928
chr9132376419132376507E07124200
chr9132376603132376837E07124384
chr9132390317132390915E07138098
chr9132390949132390997E07138730
chr9132391852132391935E07139633
chr9132391954132392219E07139735
chr9132392282132392440E07140063
chr9132392534132392737E07140315
chr9132392872132392932E07140653
chr9132392934132392988E07140715
chr9132392996132393103E07140777
chr9132394557132394611E07142338
chr9132401343132401534E07149124
chr9132401570132401812E07149351
chr9132401851132401918E07149632
chr9132310274132311896E072-40323
chr9132317736132317911E072-34308
chr9132318048132318425E072-33794
chr9132318755132322242E072-29977
chr9132323971132324630E072-27589
chr9132324671132324755E072-27464
chr9132324826132324967E072-27252
chr9132324982132325042E072-27177
chr9132328723132328813E072-23406
chr9132329032132329177E072-23042
chr9132329207132329296E072-22923
chr9132329311132329385E072-22834
chr9132329430132329525E072-22694
chr9132329675132329871E072-22348
chr9132330101132333434E072-18785
chr9132337257132337759E072-14460
chr9132337788132338594E072-13625
chr9132338609132338696E072-13523
chr9132338755132338986E072-13233
chr9132364722132365659E07212503
chr9132365779132365840E07213560
chr9132365907132365951E07213688
chr9132365991132366195E07213772
chr9132366254132366365E07214035
chr9132366409132366486E07214190
chr9132366594132366693E07214375
chr9132369133132370398E07216914
chr9132376419132376507E07224200
chr9132376603132376837E07224384
chr9132390317132390915E07238098
chr9132391543132391626E07239324
chr9132391678132391756E07239459
chr9132391852132391935E07239633
chr9132391954132392219E07239735
chr9132392872132392932E07240653
chr9132392934132392988E07240715
chr9132394557132394611E07242338
chr9132401343132401534E07249124
chr9132401570132401812E07249351
chr9132401851132401918E07249632
chr9132310274132311896E073-40323
chr9132313832132314003E073-38216
chr9132314079132314129E073-38090
chr9132314239132314308E073-37911
chr9132317736132317911E073-34308
chr9132318048132318425E073-33794
chr9132318755132322242E073-29977
chr9132323971132324630E073-27589
chr9132324671132324755E073-27464
chr9132328723132328813E073-23406
chr9132329032132329177E073-23042
chr9132329207132329296E073-22923
chr9132329311132329385E073-22834
chr9132329430132329525E073-22694
chr9132329675132329871E073-22348
chr9132329875132329995E073-22224
chr9132330101132333434E073-18785
chr9132333568132334082E073-18137
chr9132364722132365659E07312503
chr9132365779132365840E07313560
chr9132365907132365951E07313688
chr9132365991132366195E07313772
chr9132366254132366365E07314035
chr9132368728132369123E07316509
chr9132369133132370398E07316914
chr9132370506132370556E07318287
chr9132370754132370935E07318535
chr9132376419132376507E07324200
chr9132376603132376837E07324384
chr9132386343132387040E07334124
chr9132390949132390997E07338730
chr9132391086132391273E07338867
chr9132391543132391626E07339324
chr9132391678132391756E07339459
chr9132391852132391935E07339633
chr9132391954132392219E07339735
chr9132392282132392440E07340063
chr9132392534132392737E07340315
chr9132392872132392932E07340653
chr9132392934132392988E07340715
chr9132392996132393103E07340777
chr9132393133132393499E07340914
chr9132394557132394611E07342338
chr9132394794132395092E07342575
chr9132395142132395199E07342923
chr9132401343132401534E07349124
chr9132401570132401812E07349351
chr9132401851132401918E07349632
chr9132310274132311896E074-40323
chr9132313309132313370E074-38849
chr9132313462132313531E074-38688
chr9132313832132314003E074-38216
chr9132314079132314129E074-38090
chr9132314239132314308E074-37911
chr9132323971132324630E074-27589
chr9132324671132324755E074-27464
chr9132328723132328813E074-23406
chr9132329032132329177E074-23042
chr9132329207132329296E074-22923
chr9132329311132329385E074-22834
chr9132329430132329525E074-22694
chr9132329675132329871E074-22348
chr9132329875132329995E074-22224
chr9132330101132333434E074-18785
chr9132369133132370398E07416914
chr9132375147132376264E07422928
chr9132376419132376507E07424200
chr9132376603132376837E07424384
chr9132391543132391626E07439324
chr9132391678132391756E07439459
chr9132391852132391935E07439633
chr9132391954132392219E07439735
chr9132392282132392440E07440063
chr9132392534132392737E07440315
chr9132392872132392932E07440653
chr9132392934132392988E07440715
chr9132392996132393103E07440777
chr9132394094132394253E07441875
chr9132394557132394611E07442338
chr9132401570132401812E07449351
chr9132401851132401918E07449632
chr9132313309132313370E081-38849
chr9132313462132313531E081-38688
chr9132313832132314003E081-38216
chr9132314079132314129E081-38090
chr9132317736132317911E081-34308
chr9132318048132318425E081-33794
chr9132318755132322242E081-29977
chr9132323020132323804E081-28415
chr9132323824132323878E081-28341
chr9132323971132324630E081-27589
chr9132325196132325262E081-26957
chr9132328723132328813E081-23406
chr9132329032132329177E081-23042
chr9132329207132329296E081-22923
chr9132329311132329385E081-22834
chr9132329430132329525E081-22694
chr9132329675132329871E081-22348
chr9132329875132329995E081-22224
chr9132330101132333434E081-18785
chr9132364236132364282E08112017
chr9132364351132364427E08112132
chr9132364481132364563E08112262
chr9132364722132365659E08112503
chr9132365779132365840E08113560
chr9132365907132365951E08113688
chr9132365991132366195E08113772
chr9132366254132366365E08114035
chr9132366409132366486E08114190
chr9132366594132366693E08114375
chr9132366734132366782E08114515
chr9132366792132366883E08114573
chr9132366906132367002E08114687
chr9132369133132370398E08116914
chr9132370953132374010E08118734
chr9132374144132374229E08121925
chr9132375147132376264E08122928
chr9132376419132376507E08124200
chr9132376603132376837E08124384
chr9132381906132381986E08129687
chr9132390317132390915E08138098
chr9132390949132390997E08138730
chr9132307490132307594E082-44625
chr9132313309132313370E082-38849
chr9132318755132322242E082-29977
chr9132323971132324630E082-27589
chr9132324671132324755E082-27464
chr9132324826132324967E082-27252
chr9132324982132325042E082-27177
chr9132364722132365659E08212503
chr9132365779132365840E08213560
chr9132365907132365951E08213688
chr9132366409132366486E08214190
chr9132369133132370398E08216914
chr9132375147132376264E08222928
chr9132376419132376507E08224200
chr9132390949132390997E08238730
chr9132391086132391273E08238867
chr9132393133132393499E08240914
chr9132393506132393698E08241287
chr9132401570132401812E08249351
chr9132401851132401918E08249632










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9132311897132313165E067-39054
chr9132382009132383508E06729790
chr9132388137132389707E06735918
chr9132311897132313165E068-39054
chr9132382009132383508E06829790
chr9132388137132389707E06835918
chr9132311897132313165E069-39054
chr9132382009132383508E06929790
chr9132388137132389707E06935918
chr9132311897132313165E070-39054
chr9132388137132389707E07035918
chr9132311897132313165E071-39054
chr9132382009132383508E07129790
chr9132388137132389707E07135918
chr9132311897132313165E072-39054
chr9132382009132383508E07229790
chr9132388137132389707E07235918
chr9132311897132313165E073-39054
chr9132382009132383508E07329790
chr9132388137132389707E07335918
chr9132311897132313165E074-39054
chr9132382009132383508E07429790
chr9132388137132389707E07435918
chr9132388137132389707E08135918
chr9132311897132313165E082-39054
chr9132388137132389707E08235918