rs10997361

Homo sapiens
C>T
CTNNA3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0261 (7837/29930,GnomAD)
T=0210 (6133/29118,TOPMED)
T=0381 (1906/5008,1000G)
T=0256 (986/3854,ALSPAC)
T=0250 (927/3708,TWINSUK)
chr10:66722696 (GRCh38.p7) (10q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.66722696C>T
GRCh37.p13 chr 10NC_000010.10:g.68482454C>T
CTNNA3 RefSeqGeneNG_034072.1:g.978496G>A

Gene: CTNNA3, catenin alpha 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
CTNNA3 transcript variant 2NM_001127384.2:c.N/AIntron Variant
CTNNA3 transcript variant 1NM_013266.3:c.N/AIntron Variant
CTNNA3 transcript variant 3NM_001291133.1:c.N/AGenic Downstream Transcript Variant
CTNNA3 transcript variant X1XM_017016151.1:c.N/AIntron Variant
CTNNA3 transcript variant X2XM_017016152.1:c.N/AIntron Variant
CTNNA3 transcript variant X3XM_017016153.1:c.N/AIntron Variant
CTNNA3 transcript variant X4XM_017016154.1:c.N/AIntron Variant
CTNNA3 transcript variant X5XM_017016155.1:c.N/AIntron Variant
CTNNA3 transcript variant X6XM_017016156.1:c.N/AIntron Variant
CTNNA3 transcript variant X7XM_017016157.1:c.N/AIntron Variant
CTNNA3 transcript variant X8XM_017016158.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.934T=0.066
1000GenomesAmericanSub694C=0.500T=0.500
1000GenomesEast AsianSub1008C=0.208T=0.792
1000GenomesEuropeSub1006C=0.702T=0.298
1000GenomesGlobalStudy-wide5008C=0.619T=0.381
1000GenomesSouth AsianSub978C=0.620T=0.380
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.744T=0.256
The Genome Aggregation DatabaseAfricanSub8716C=0.917T=0.083
The Genome Aggregation DatabaseAmericanSub836C=0.500T=0.500
The Genome Aggregation DatabaseEast AsianSub1612C=0.179T=0.821
The Genome Aggregation DatabaseEuropeSub18464C=0.714T=0.285
The Genome Aggregation DatabaseGlobalStudy-wide29930C=0.738T=0.261
The Genome Aggregation DatabaseOtherSub302C=0.660T=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.789T=0.210
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.750T=0.250
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs109973610.000294alcohol dependence20201924

eQTL of rs10997361 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10997361 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr106848353068483599E0671076
chr106848353068483599E0691076
chr106848369568483990E0691241
chr106848411068484288E0701656
chr106848353068483599E0711076
chr106848369568483990E0711241
chr106848411068484288E0711656
chr106848353068483599E0721076
chr106848369568483990E0721241
chr106848411068484288E0721656
chr106850636968506750E08123915
chr106848353068483599E0821076
chr106848369568483990E0821241
chr106852043968521142E08237985