rs11004819

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0340 (10182/29908,GnomAD)
T=0288 (8403/29118,TOPMED)
T=0269 (1348/5008,1000G)
T=0469 (1806/3854,ALSPAC)
T=0468 (1735/3708,TWINSUK)
chr10:50253880 (GRCh38.p7) (10q11.23)
OD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.50253880C>T
GRCh37.p13 chr 10NC_000010.10:g.52013640C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.970T=0.030
1000GenomesAmericanSub694C=0.580T=0.420
1000GenomesEast AsianSub1008C=0.699T=0.301
1000GenomesEuropeSub1006C=0.521T=0.479
1000GenomesGlobalStudy-wide5008C=0.731T=0.269
1000GenomesSouth AsianSub978C=0.760T=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.531T=0.469
The Genome Aggregation DatabaseAfricanSub8714C=0.903T=0.097
The Genome Aggregation DatabaseAmericanSub832C=0.600T=0.400
The Genome Aggregation DatabaseEast AsianSub1616C=0.694T=0.306
The Genome Aggregation DatabaseEuropeSub18444C=0.544T=0.455
The Genome Aggregation DatabaseGlobalStudy-wide29908C=0.659T=0.340
The Genome Aggregation DatabaseOtherSub302C=0.640T=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.711T=0.288
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.532T=0.468
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs110048191.29E-05Opioid sensitivity23183491

eQTL of rs11004819 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11004819 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr105204594852047526E06832308
chr105204594852047526E06932308
chr105204594852047526E07132308
chr105204594852047526E07232308
chr105205140752051561E07437767
chr105204571152045761E08132071
chr105204594852047526E08132308
chr105204762152047698E08133981
chr105204773052047795E08134090
chr105204779652047872E08134156