rs11023182

Homo sapiens
G>T
RRAS2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0163 (4889/29934,GnomAD)
T=0142 (4136/29118,TOPMED)
T=0158 (793/5008,1000G)
T=0111 (428/3854,ALSPAC)
T=0111 (413/3708,TWINSUK)
chr11:14297284 (GRCh38.p7) (11p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
150 Enhancers around
123 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.14297284G>T
GRCh37.p13 chr 11 fix patch HG256_PATCHNW_003871075.1:g.355368G>T
RRAS2 RefSeqGeneNG_017058.1:g.72223C>A
GRCh37.p13 chr 11NC_000011.9:g.14318830G>T

Gene: RRAS2, related RAS viral (r-ras) oncogene homolog 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
RRAS2 transcript variant 2NM_001102669.2:c.N/AIntron Variant
RRAS2 transcript variant 3NM_001177314.1:c.N/AIntron Variant
RRAS2 transcript variant 4NM_001177315.1:c.N/AIntron Variant
RRAS2 transcript variant 1NM_012250.5:c.N/AIntron Variant
RRAS2 transcript variant X1XM_017017363.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.765T=0.235
1000GenomesAmericanSub694G=0.910T=0.090
1000GenomesEast AsianSub1008G=0.810T=0.190
1000GenomesEuropeSub1006G=0.875T=0.125
1000GenomesGlobalStudy-wide5008G=0.842T=0.158
1000GenomesSouth AsianSub978G=0.900T=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.889T=0.111
The Genome Aggregation DatabaseAfricanSub8708G=0.805T=0.195
The Genome Aggregation DatabaseAmericanSub836G=0.920T=0.080
The Genome Aggregation DatabaseEast AsianSub1618G=0.813T=0.187
The Genome Aggregation DatabaseEuropeSub18470G=0.849T=0.150
The Genome Aggregation DatabaseGlobalStudy-wide29934G=0.836T=0.163
The Genome Aggregation DatabaseOtherSub302G=0.870T=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.858T=0.142
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.889T=0.111
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs110231820.0003alcohol dependence20201924

eQTL of rs11023182 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11023182 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11326111326237E067-29131
chr11326242327852E067-27516
chr11350483351410E067-3958
chr11357716357804E0672348
chr11357812357955E0672444
chr11371159371508E06715791
chr11373524373653E06718156
chr11373706373842E06718338
chr11373933374381E06718565
chr11374494374544E06719126
chr11325785325883E068-29485
chr11325989326101E068-29267
chr11326111326237E068-29131
chr11326242327852E068-27516
chr11328032328197E068-27171
chr11328293328580E068-26788
chr11335536337159E068-18209
chr11352587352772E068-2596
chr11352835354238E068-1130
chr11371159371508E06815791
chr11371557371756E06816189
chr11371764372056E06816396
chr11373382373446E06818014
chr11373524373653E06818156
chr11373706373842E06818338
chr11373933374381E06818565
chr11325785325883E069-29485
chr11325989326101E069-29267
chr11326111326237E069-29131
chr11326242327852E069-27516
chr11334067334975E069-20393
chr11335536337159E069-18209
chr11350483351410E069-3958
chr11352587352772E069-2596
chr11352835354238E069-1130
chr11371159371508E06915791
chr11371557371756E06916189
chr11371764372056E06916396
chr11372084372449E06916716
chr11372467372517E06917099
chr11372589372629E06917221
chr11372705372755E06917337
chr11372868372918E06917500
chr11373092373155E06917724
chr11373382373446E06918014
chr11373524373653E06918156
chr11373706373842E06918338
chr11373933374381E06918565
chr11375224375389E06919856
chr11375416375564E06920048
chr11387566387802E07032198
chr11387882387974E07032514
chr11388173388259E07032805
chr11324235324896E071-30472
chr11324977325190E071-30178
chr11325210325319E071-30049
chr11325321325401E071-29967
chr11325544325588E071-29780
chr11325633325706E071-29662
chr11325785325883E071-29485
chr11325989326101E071-29267
chr11326111326237E071-29131
chr11326242327852E071-27516
chr11328032328197E071-27171
chr11328293328580E071-26788
chr11335148335188E071-20180
chr11335250335303E071-20065
chr11335413335497E071-19871
chr11335536337159E071-18209
chr11337609337659E071-17709
chr11349879350005E071-5363
chr11350175350272E071-5096
chr11350483351410E071-3958
chr11352587352772E071-2596
chr11352835354238E071-1130
chr11371159371508E07115791
chr11371557371756E07116189
chr11371764372056E07116396
chr11372084372449E07116716
chr11373524373653E07118156
chr11373706373842E07118338
chr11321320321364E072-34004
chr11326111326237E072-29131
chr11326242327852E072-27516
chr11335536337159E072-18209
chr11349623349683E072-5685
chr11349879350005E072-5363
chr11350175350272E072-5096
chr11352835354238E072-1130
chr11371159371508E07215791
chr11371557371756E07216189
chr11371764372056E07216396
chr11372084372449E07216716
chr11373382373446E07218014
chr11373524373653E07218156
chr11373706373842E07218338
chr11375224375389E07219856
chr11375416375564E07220048
chr11405211405360E07249843
chr11306621306699E073-48669
chr11324235324896E073-30472
chr11324977325190E073-30178
chr11326111326237E073-29131
chr11326242327852E073-27516
chr11335536337159E073-18209
chr11342185342386E073-12982
chr11342390342745E073-12623
chr11352444352550E073-2818
chr11352587352772E073-2596
chr11352835354238E073-1130
chr11371557371756E07316189
chr11371764372056E07316396
chr11372084372449E07316716
chr11372467372517E07317099
chr11372589372629E07317221
chr11372705372755E07317337
chr11372868372918E07317500
chr11373092373155E07317724
chr11373382373446E07318014
chr11373524373653E07318156
chr11373706373842E07318338
chr11373933374381E07318565
chr11374494374544E07319126
chr11375416375564E07320048
chr11375787376003E07320419
chr11324235324896E074-30472
chr11324977325190E074-30178
chr11325210325319E074-30049
chr11325321325401E074-29967
chr11325544325588E074-29780
chr11325633325706E074-29662
chr11325785325883E074-29485
chr11325989326101E074-29267
chr11326111326237E074-29131
chr11326242327852E074-27516
chr11335536337159E074-18209
chr11350483351410E074-3958
chr11352444352550E074-2818
chr11352587352772E074-2596
chr11352835354238E074-1130
chr11373706373842E07418338
chr11373933374381E07418565
chr11374494374544E07419126
chr11371159371508E08115791
chr11371557371756E08116189
chr11371764372056E08116396
chr11372084372449E08116716
chr11372084372449E08216716
chr11372467372517E08217099
chr11372589372629E08217221










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11307747308462E067-46906
chr11308510308648E067-46720
chr11308882308946E067-46422
chr11309107309706E067-45662
chr11309723310261E067-45107
chr11314442314663E067-40705
chr11314994315872E067-39496
chr11315976317972E067-37396
chr11319525319915E067-35453
chr11320038320102E067-35266
chr11320332321239E067-34129
chr11368932369004E06713564
chr11370057370956E06714689
chr11307747308462E068-46906
chr11308510308648E068-46720
chr11308882308946E068-46422
chr11309107309706E068-45662
chr11309723310261E068-45107
chr11314442314663E068-40705
chr11314994315872E068-39496
chr11315976317972E068-37396
chr11318953319019E068-36349
chr11319198319265E068-36103
chr11319525319915E068-35453
chr11320038320102E068-35266
chr11320332321239E068-34129
chr11368932369004E06813564
chr11369769370052E06814401
chr11370057370956E06814689
chr11307747308462E069-46906
chr11308510308648E069-46720
chr11308882308946E069-46422
chr11309107309706E069-45662
chr11309723310261E069-45107
chr11314442314663E069-40705
chr11314994315872E069-39496
chr11319525319915E069-35453
chr11320038320102E069-35266
chr11320332321239E069-34129
chr11368932369004E06913564
chr11369769370052E06914401
chr11370057370956E06914689
chr11318953319019E070-36349
chr11319198319265E070-36103
chr11319525319915E070-35453
chr11320038320102E070-35266
chr11320332321239E070-34129
chr11368932369004E07013564
chr11369056369084E07013688
chr11369098369261E07013730
chr11369300369768E07013932
chr11369769370052E07014401
chr11370057370956E07014689
chr11307747308462E071-46906
chr11308510308648E071-46720
chr11308882308946E071-46422
chr11309107309706E071-45662
chr11309723310261E071-45107
chr11314442314663E071-40705
chr11314994315872E071-39496
chr11315976317972E071-37396
chr11318953319019E071-36349
chr11319198319265E071-36103
chr11319525319915E071-35453
chr11320038320102E071-35266
chr11320332321239E071-34129
chr11370057370956E07114689
chr11307747308462E072-46906
chr11308510308648E072-46720
chr11308882308946E072-46422
chr11309107309706E072-45662
chr11309723310261E072-45107
chr11314442314663E072-40705
chr11314994315872E072-39496
chr11315976317972E072-37396
chr11318953319019E072-36349
chr11319198319265E072-36103
chr11319525319915E072-35453
chr11320038320102E072-35266
chr11320332321239E072-34129
chr11368932369004E07213564
chr11369769370052E07214401
chr11370057370956E07214689
chr11307747308462E073-46906
chr11308510308648E073-46720
chr11308882308946E073-46422
chr11309107309706E073-45662
chr11309723310261E073-45107
chr11314442314663E073-40705
chr11314994315872E073-39496
chr11315976317972E073-37396
chr11318953319019E073-36349
chr11319198319265E073-36103
chr11319525319915E073-35453
chr11320038320102E073-35266
chr11320332321239E073-34129
chr11368932369004E07313564
chr11369769370052E07314401
chr11370057370956E07314689
chr11308510308648E074-46720
chr11308882308946E074-46422
chr11309107309706E074-45662
chr11309723310261E074-45107
chr11314994315872E074-39496
chr11318953319019E074-36349
chr11319198319265E074-36103
chr11319525319915E074-35453
chr11320038320102E074-35266
chr11320332321239E074-34129
chr11368932369004E07413564
chr11370057370956E07414689
chr11368932369004E08113564
chr11318953319019E082-36349
chr11319198319265E082-36103
chr11319525319915E082-35453
chr11320038320102E082-35266
chr11320332321239E082-34129
chr11368932369004E08213564
chr11369056369084E08213688
chr11369098369261E08213730
chr11369300369768E08213932
chr11369769370052E08214401
chr11370057370956E08214689