rs11028019

Homo sapiens
T>C
LUZP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0074 (2223/29884,GnomAD)
C=0068 (2007/29118,TOPMED)
C=0051 (255/5008,1000G)
C=0089 (343/3854,ALSPAC)
C=0082 (304/3708,TWINSUK)
chr11:24562345 (GRCh38.p7) (11p14.3)
ND
GWASdb2
1   publication(s)
See rs on genome
11 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.24562345T>C
GRCh37.p13 chr 11NC_000011.9:g.24583891T>C
LUZP2 RefSeqGeneNG_030588.1:g.70376T>C

Gene: LUZP2, leucine zipper protein 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LUZP2 transcript variant 1NM_001009909.3:c.N/AIntron Variant
LUZP2 transcript variant 2NM_001252008.1:c.N/AIntron Variant
LUZP2 transcript variant 3NM_001252010.1:c.N/AIntron Variant
LUZP2 transcript variant X4XM_011520056.2:c.N/AIntron Variant
LUZP2 transcript variant X1XM_017017648.1:c.N/AIntron Variant
LUZP2 transcript variant X2XM_017017649.1:c.N/AIntron Variant
LUZP2 transcript variant X5XM_017017650.1:c.N/AIntron Variant
LUZP2 transcript variant X6XM_017017651.1:c.N/AIntron Variant
LUZP2 transcript variant X3XR_930864.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.991C=0.009
1000GenomesAmericanSub694T=0.860C=0.140
1000GenomesEast AsianSub1008T=0.974C=0.026
1000GenomesEuropeSub1006T=0.912C=0.088
1000GenomesGlobalStudy-wide5008T=0.949C=0.051
1000GenomesSouth AsianSub978T=0.970C=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.911C=0.089
The Genome Aggregation DatabaseAfricanSub8710T=0.975C=0.025
The Genome Aggregation DatabaseAmericanSub834T=0.850C=0.150
The Genome Aggregation DatabaseEast AsianSub1618T=0.964C=0.036
The Genome Aggregation DatabaseEuropeSub18420T=0.901C=0.098
The Genome Aggregation DatabaseGlobalStudy-wide29884T=0.925C=0.074
The Genome Aggregation DatabaseOtherSub302T=0.980C=0.020
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.931C=0.068
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.918C=0.082
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs110280190.000697nicotine smoking19268276

eQTL of rs11028019 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11028019 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr112462013324620206E07036242
chr112462026124620657E07036370
chr112462068124620742E07036790
chr112462013324620206E07436242
chr112462026124620657E07436370
chr112453523524535761E081-48130
chr112453584324536029E081-47862
chr112459390024594347E08110009
chr112453501624535148E082-48743
chr112453523524535761E082-48130
chr112453584324536029E082-47862