rs11041680

Homo sapiens
G>A
OR10A3 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0322 (9625/29874,GnomAD)
A=0315 (9196/29118,TOPMED)
A=0317 (1586/5008,1000G)
A=0377 (1454/3854,ALSPAC)
A=0373 (1383/3708,TWINSUK)
chr11:7940250 (GRCh38.p7) (11p15.4)
AD
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
31 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.7940250G>A
GRCh37.p13 chr 11NC_000011.9:g.7961797G>A
GRCh38.p7 chr 11 novel patch HSCHR11_1_CTG1_2NW_011332695.1:g.171244G>A
GRCh38.p7 chr 11 alt locus HSCHR11_1_CTG5NT_187583.1:g.171751G>A

Gene: OR10A3, olfactory receptor family 10 subfamily A member 3(minus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
OR10A3 transcriptNM_001003745.1:c.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.771A=0.229
1000GenomesAmericanSub694G=0.560A=0.440
1000GenomesEast AsianSub1008G=0.734A=0.266
1000GenomesEuropeSub1006G=0.651A=0.349
1000GenomesGlobalStudy-wide5008G=0.683A=0.317
1000GenomesSouth AsianSub978G=0.640A=0.360
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.623A=0.377
The Genome Aggregation DatabaseAfricanSub8696G=0.749A=0.251
The Genome Aggregation DatabaseAmericanSub830G=0.560A=0.440
The Genome Aggregation DatabaseEast AsianSub1608G=0.711A=0.289
The Genome Aggregation DatabaseEuropeSub18442G=0.645A=0.355
The Genome Aggregation DatabaseGlobalStudy-wide29874G=0.677A=0.322
The Genome Aggregation DatabaseOtherSub298G=0.770A=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.684A=0.315
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.627A=0.373
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs110416804.61E-05alcohol consumption23953852

eQTL of rs11041680 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11041680 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1180076118007848E06745814
chr1180105818010710E06748784
chr1180116968011736E06749899
chr1180076118007848E06845814
chr1180105818010710E06848784
chr1180076118007848E06945814
chr1180105818010710E06948784
chr1179858687986265E07024071
chr1180076118007848E07045814
chr1180105818010710E07048784
chr1180105818010710E07148784
chr1180116968011736E07149899
chr1180072428007477E07245445
chr1180075268007574E07245729
chr1180076118007848E07245814
chr1180105818010710E07248784
chr1180076118007848E07345814
chr1180105818010710E07348784
chr1180076118007848E07445814
chr1180105818010710E07448784
chr1179858687986265E08224071
chr1180069938007037E08245196
chr1180072428007477E08245445
chr1180075268007574E08245729
chr1180076118007848E08245814
chr1180105818010710E08248784
chr1180116968011736E08249899









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1180078508009092E06746053
chr1180092438009487E06747446
chr1180094988009671E06747701
chr1180078508009092E06846053
chr1180092438009487E06847446
chr1180094988009671E06847701
chr1180078508009092E06946053
chr1180092438009487E06947446
chr1180094988009671E06947701
chr1180078508009092E07046053
chr1180092438009487E07047446
chr1180094988009671E07047701
chr1180078508009092E07146053
chr1180092438009487E07147446
chr1180094988009671E07147701
chr1180078508009092E07246053
chr1180092438009487E07247446
chr1180094988009671E07247701
chr1180078508009092E07346053
chr1180092438009487E07347446
chr1180094988009671E07347701
chr1179492487949467E074-12330
chr1179494767949625E074-12172
chr1180078508009092E07446053
chr1180092438009487E07447446
chr1180094988009671E07447701
chr1180092438009487E08147446
chr1180094988009671E08147701
chr1180078508009092E08246053
chr1180092438009487E08247446
chr1180094988009671E08247701