rs11051507

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0344 (10293/29880,GnomAD)
C==0412 (12004/29118,TOPMED)
C==0345 (1730/5008,1000G)
C==0285 (1099/3854,ALSPAC)
C==0259 (961/3708,TWINSUK)
chr12:31642430 (GRCh38.p7) (12p11.21)
ND
GWASdb2
1   publication(s)
See rs on genome
11 Enhancers around
28 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.31642430C>A
GRCh37.p13 chr 12NC_000012.11:g.31795364C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.623A=0.377
1000GenomesAmericanSub694C=0.340A=0.660
1000GenomesEast AsianSub1008C=0.241A=0.759
1000GenomesEuropeSub1006C=0.236A=0.764
1000GenomesGlobalStudy-wide5008C=0.345A=0.655
1000GenomesSouth AsianSub978C=0.190A=0.810
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.285A=0.715
The Genome Aggregation DatabaseAfricanSub8680C=0.588A=0.412
The Genome Aggregation DatabaseAmericanSub836C=0.360A=0.640
The Genome Aggregation DatabaseEast AsianSub1620C=0.252A=0.748
The Genome Aggregation DatabaseEuropeSub18442C=0.239A=0.761
The Genome Aggregation DatabaseGlobalStudy-wide29880C=0.344A=0.655
The Genome Aggregation DatabaseOtherSub302C=0.230A=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.412A=0.587
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.259A=0.741
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs110515072.07E-05alcohol and nictotine co-dependence20158304

eQTL of rs11051507 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11051507 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr123180592731806031E06810563
chr123180609131806603E06810727
chr123180592731806031E06910563
chr123180609131806603E06910727
chr123182662731827095E06931263
chr123179880231799253E0703438
chr123180592731806031E07110563
chr123180609131806603E07110727
chr123181126831811339E07215904
chr123182650131826580E07431137
chr123181126831811339E08215904







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr123181135431812898E06715990
chr123181295131813026E06717587
chr123181314831813420E06717784
chr123181135431812898E06815990
chr123181295131813026E06817587
chr123181314831813420E06817784
chr123181135431812898E06915990
chr123181295131813026E06917587
chr123181314831813420E06917784
chr123181135431812898E07015990
chr123181295131813026E07017587
chr123181135431812898E07115990
chr123181295131813026E07117587
chr123181314831813420E07117784
chr123181135431812898E07215990
chr123181295131813026E07217587
chr123181314831813420E07217784
chr123181135431812898E07315990
chr123181295131813026E07317587
chr123181314831813420E07317784
chr123181135431812898E07415990
chr123181295131813026E07417587
chr123181314831813420E07417784
chr123181135431812898E08115990
chr123181295131813026E08117587
chr123181135431812898E08215990
chr123181295131813026E08217587
chr123181314831813420E08217784