rs11057750

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0180 (5404/29930,GnomAD)
G=0205 (5974/29118,TOPMED)
G=0256 (1280/5008,1000G)
G=0182 (702/3854,ALSPAC)
G=0177 (655/3708,TWINSUK)
chr12:124674216 (GRCh38.p7) (12q24.31)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.124674216A>G
GRCh37.p13 chr 12NC_000012.11:g.125158762A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.825G=0.175
1000GenomesAmericanSub694A=0.740G=0.260
1000GenomesEast AsianSub1008A=0.487G=0.513
1000GenomesEuropeSub1006A=0.829G=0.171
1000GenomesGlobalStudy-wide5008A=0.744G=0.256
1000GenomesSouth AsianSub978A=0.810G=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.818G=0.182
The Genome Aggregation DatabaseAfricanSub8712A=0.826G=0.174
The Genome Aggregation DatabaseAmericanSub838A=0.780G=0.220
The Genome Aggregation DatabaseEast AsianSub1610A=0.450G=0.550
The Genome Aggregation DatabaseEuropeSub18468A=0.851G=0.148
The Genome Aggregation DatabaseGlobalStudy-wide29930A=0.819G=0.180
The Genome Aggregation DatabaseOtherSub302A=0.740G=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.794G=0.205
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.823G=0.177
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs110577500.000759alcohol dependence24277619

eQTL of rs11057750 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11057750 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12125135402125136193E067-22569
chr12125136240125136378E067-22384
chr12125136470125136799E067-21963
chr12125136816125136958E067-21804
chr12125136984125137167E067-21595
chr12125138971125139382E067-19380
chr12125141051125141148E067-17614
chr12125141171125141267E067-17495
chr12125141316125141448E067-17314
chr12125145322125145426E067-13336
chr12125145486125145955E067-12807
chr12125145963125146300E067-12462
chr12125146359125146558E067-12204
chr12125147374125147432E067-11330
chr12125147707125147769E067-10993
chr12125147816125148246E067-10516
chr12125148457125148915E067-9847
chr12125149224125149708E067-9054
chr12125149771125149886E067-8876
chr12125153101125153489E067-5273
chr12125153502125153614E067-5148
chr12125158176125158290E067-472
chr12125158382125159152E0670
chr12125159155125159398E067393
chr12125159440125159484E067678
chr12125159495125159589E067733
chr12125159774125159894E0671012
chr12125159912125160055E0671150
chr12125160116125160223E0671354
chr12125160300125161458E0671538
chr12125163497125163865E0674735
chr12125163879125164024E0675117
chr12125164029125164567E0675267
chr12125164655125164857E0675893
chr12125169048125173565E06710286
chr12125179321125180038E06720559
chr12125181198125181248E06722436
chr12125181318125181610E06722556
chr12125181688125181771E06722926
chr12125181778125181964E06723016
chr12125183979125184260E06725217
chr12125184291125184376E06725529
chr12125185360125186174E06726598
chr12125186178125186308E06727416
chr12125201187125201421E06742425
chr12125201540125201672E06742778
chr12125201673125201885E06742911
chr12125201949125201989E06743187
chr12125202023125202126E06743261
chr12125202536125202590E06743774
chr12125202757125202830E06743995
chr12125203215125203324E06744453
chr12125203515125203606E06744753
chr12125203758125203817E06744996
chr12125203849125204150E06745087
chr12125204228125204302E06745466
chr12125204418125204468E06745656
chr12125204523125206155E06745761
chr12125120631125121424E068-37338
chr12125123809125124388E068-34374
chr12125135402125136193E068-22569
chr12125136240125136378E068-22384
chr12125136470125136799E068-21963
chr12125136816125136958E068-21804
chr12125136984125137167E068-21595
chr12125137345125137395E068-21367
chr12125137454125138448E068-20314
chr12125138535125138665E068-20097
chr12125138971125139382E068-19380
chr12125141051125141148E068-17614
chr12125141171125141267E068-17495
chr12125141316125141448E068-17314
chr12125141486125141587E068-17175
chr12125144644125144724E068-14038
chr12125144727125144890E068-13872
chr12125145322125145426E068-13336
chr12125145486125145955E068-12807
chr12125145963125146300E068-12462
chr12125146359125146558E068-12204
chr12125146611125146675E068-12087
chr12125146833125146955E068-11807
chr12125146965125147049E068-11713
chr12125147138125147224E068-11538
chr12125147374125147432E068-11330
chr12125147707125147769E068-10993
chr12125147816125148246E068-10516
chr12125148457125148915E068-9847
chr12125149224125149708E068-9054
chr12125149771125149886E068-8876
chr12125153101125153489E068-5273
chr12125153502125153614E068-5148
chr12125158382125159152E0680
chr12125159155125159398E068393
chr12125159440125159484E068678
chr12125159495125159589E068733
chr12125159774125159894E0681012
chr12125159912125160055E0681150
chr12125160116125160223E0681354
chr12125160300125161458E0681538
chr12125161560125161676E0682798
chr12125162890125163495E0684128
chr12125163497125163865E0684735
chr12125163879125164024E0685117
chr12125164029125164567E0685267
chr12125164655125164857E0685893
chr12125165759125167271E0686997
chr12125168251125168388E0689489
chr12125168419125168567E0689657
chr12125169048125173565E06810286
chr12125179321125180038E06820559
chr12125180434125180732E06821672
chr12125180892125181016E06822130
chr12125181033125181115E06822271
chr12125181198125181248E06822436
chr12125181318125181610E06822556
chr12125181688125181771E06822926
chr12125181778125181964E06823016
chr12125182132125182250E06823370
chr12125182454125182504E06823692
chr12125182616125183816E06823854
chr12125183979125184260E06825217
chr12125184291125184376E06825529
chr12125184438125184713E06825676
chr12125184765125184919E06826003
chr12125185027125185077E06826265
chr12125185150125185315E06826388
chr12125185360125186174E06826598
chr12125186178125186308E06827416
chr12125197424125198795E06838662
chr12125198933125199019E06840171
chr12125199075125199257E06840313
chr12125199285125199335E06840523
chr12125199830125199932E06841068
chr12125199933125200565E06841171
chr12125204523125206155E06845761
chr12125110426125111515E069-47247
chr12125111600125111970E069-46792
chr12125135152125135319E069-23443
chr12125135402125136193E069-22569
chr12125136240125136378E069-22384
chr12125136470125136799E069-21963
chr12125136816125136958E069-21804
chr12125136984125137167E069-21595
chr12125137345125137395E069-21367
chr12125137454125138448E069-20314
chr12125141051125141148E069-17614
chr12125141171125141267E069-17495
chr12125141316125141448E069-17314
chr12125141486125141587E069-17175
chr12125144727125144890E069-13872
chr12125145322125145426E069-13336
chr12125145486125145955E069-12807
chr12125145963125146300E069-12462
chr12125146359125146558E069-12204
chr12125146611125146675E069-12087
chr12125146833125146955E069-11807
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chr12125147138125147224E069-11538
chr12125147374125147432E069-11330
chr12125147707125147769E069-10993
chr12125147816125148246E069-10516
chr12125153101125153489E069-5273
chr12125153502125153614E069-5148
chr12125158176125158290E069-472
chr12125158382125159152E0690
chr12125159155125159398E069393
chr12125159440125159484E069678
chr12125159495125159589E069733
chr12125159774125159894E0691012
chr12125159912125160055E0691150
chr12125160116125160223E0691354
chr12125160300125161458E0691538
chr12125162890125163495E0694128
chr12125163497125163865E0694735
chr12125163879125164024E0695117
chr12125164029125164567E0695267
chr12125164655125164857E0695893
chr12125165759125167271E0696997
chr12125169048125173565E06910286
chr12125179321125180038E06920559
chr12125180892125181016E06922130
chr12125181033125181115E06922271
chr12125181198125181248E06922436
chr12125181318125181610E06922556
chr12125181688125181771E06922926
chr12125181778125181964E06923016
chr12125182132125182250E06923370
chr12125182454125182504E06923692
chr12125182616125183816E06923854
chr12125183979125184260E06925217
chr12125184291125184376E06925529
chr12125184438125184713E06925676
chr12125184765125184919E06926003
chr12125185027125185077E06926265
chr12125185150125185315E06926388
chr12125185360125186174E06926598
chr12125199830125199932E06941068
chr12125199933125200565E06941171
chr12125200598125200652E06941836
chr12125201187125201421E06942425
chr12125201540125201672E06942778
chr12125201673125201885E06942911
chr12125202757125202830E06943995
chr12125203215125203324E06944453
chr12125203515125203606E06944753
chr12125203758125203817E06944996
chr12125203849125204150E06945087
chr12125204228125204302E06945466
chr12125204418125204468E06945656
chr12125204523125206155E06945761
chr12125137454125138448E070-20314
chr12125138535125138665E070-20097
chr12125138971125139382E070-19380
chr12125141051125141148E070-17614
chr12125141171125141267E070-17495
chr12125141316125141448E070-17314
chr12125141486125141587E070-17175
chr12125141623125141835E070-16927
chr12125141856125141987E070-16775
chr12125141991125142051E070-16711
chr12125144727125144890E070-13872
chr12125145322125145426E070-13336
chr12125145486125145955E070-12807
chr12125145963125146300E070-12462
chr12125146359125146558E070-12204
chr12125158382125159152E0700
chr12125159912125160055E0701150
chr12125160116125160223E0701354
chr12125160300125161458E0701538
chr12125162890125163495E0704128
chr12125163497125163865E0704735
chr12125163879125164024E0705117
chr12125164029125164567E0705267
chr12125164655125164857E0705893
chr12125169048125173565E07010286
chr12125181318125181610E07022556
chr12125181688125181771E07022926
chr12125181778125181964E07023016
chr12125182616125183816E07023854
chr12125189129125189461E07030367
chr12125189939125190084E07031177
chr12125190234125190726E07031472
chr12125190966125191150E07032204
chr12125191309125191359E07032547
chr12125203515125203606E07044753
chr12125203758125203817E07044996
chr12125203849125204150E07045087
chr12125204228125204302E07045466
chr12125204418125204468E07045656
chr12125204523125206155E07045761
chr12125206244125206954E07047482
chr12125110426125111515E071-47247
chr12125111600125111970E071-46792
chr12125120631125121424E071-37338
chr12125135152125135319E071-23443
chr12125135402125136193E071-22569
chr12125136240125136378E071-22384
chr12125136470125136799E071-21963
chr12125136816125136958E071-21804
chr12125136984125137167E071-21595
chr12125137345125137395E071-21367
chr12125137454125138448E071-20314
chr12125138535125138665E071-20097
chr12125138971125139382E071-19380
chr12125141051125141148E071-17614
chr12125141171125141267E071-17495
chr12125141316125141448E071-17314
chr12125141486125141587E071-17175
chr12125141623125141835E071-16927
chr12125144727125144890E071-13872
chr12125145963125146300E071-12462
chr12125146359125146558E071-12204
chr12125146611125146675E071-12087
chr12125146833125146955E071-11807
chr12125146965125147049E071-11713
chr12125147138125147224E071-11538
chr12125147374125147432E071-11330
chr12125147707125147769E071-10993
chr12125147816125148246E071-10516
chr12125148457125148915E071-9847
chr12125153101125153489E071-5273
chr12125153502125153614E071-5148
chr12125158176125158290E071-472
chr12125158382125159152E0710
chr12125159155125159398E071393
chr12125159440125159484E071678
chr12125159495125159589E071733
chr12125159774125159894E0711012
chr12125159912125160055E0711150
chr12125160116125160223E0711354
chr12125160300125161458E0711538
chr12125161560125161676E0712798
chr12125162890125163495E0714128
chr12125163497125163865E0714735
chr12125163879125164024E0715117
chr12125164029125164567E0715267
chr12125164655125164857E0715893
chr12125165759125167271E0716997
chr12125167278125167433E0718516
chr12125168419125168567E0719657
chr12125169048125173565E07110286
chr12125178872125179264E07120110
chr12125179321125180038E07120559
chr12125180434125180732E07121672
chr12125180892125181016E07122130
chr12125181033125181115E07122271
chr12125181198125181248E07122436
chr12125181318125181610E07122556
chr12125181688125181771E07122926
chr12125181778125181964E07123016
chr12125182132125182250E07123370
chr12125182454125182504E07123692
chr12125183979125184260E07125217
chr12125184291125184376E07125529
chr12125184438125184713E07125676
chr12125184765125184919E07126003
chr12125185027125185077E07126265
chr12125185150125185315E07126388
chr12125185360125186174E07126598
chr12125186178125186308E07127416
chr12125201540125201672E07142778
chr12125201673125201885E07142911
chr12125201949125201989E07143187
chr12125202023125202126E07143261
chr12125202536125202590E07143774
chr12125202757125202830E07143995
chr12125203215125203324E07144453
chr12125203515125203606E07144753
chr12125203758125203817E07144996
chr12125203849125204150E07145087
chr12125204228125204302E07145466
chr12125204418125204468E07145656
chr12125204523125206155E07145761
chr12125206244125206954E07147482
chr12125110426125111515E072-47247
chr12125120299125120610E072-38152
chr12125120631125121424E072-37338
chr12125135152125135319E072-23443
chr12125135402125136193E072-22569
chr12125136240125136378E072-22384
chr12125136470125136799E072-21963
chr12125136816125136958E072-21804
chr12125136984125137167E072-21595
chr12125137345125137395E072-21367
chr12125137454125138448E072-20314
chr12125141051125141148E072-17614
chr12125141171125141267E072-17495
chr12125141316125141448E072-17314
chr12125141486125141587E072-17175
chr12125145322125145426E072-13336
chr12125145963125146300E072-12462
chr12125146359125146558E072-12204
chr12125147374125147432E072-11330
chr12125147707125147769E072-10993
chr12125147816125148246E072-10516
chr12125148457125148915E072-9847
chr12125149224125149708E072-9054
chr12125158382125159152E0720
chr12125159155125159398E072393
chr12125159440125159484E072678
chr12125159495125159589E072733
chr12125159774125159894E0721012
chr12125159912125160055E0721150
chr12125160116125160223E0721354
chr12125160300125161458E0721538
chr12125161560125161676E0722798
chr12125161690125161734E0722928
chr12125161771125161960E0723009
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chr12125163497125163865E0724735
chr12125163879125164024E0725117
chr12125164029125164567E0725267
chr12125164655125164857E0725893
chr12125164982125165032E0726220
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chr12125181778125181964E07223016
chr12125182132125182250E07223370
chr12125182454125182504E07223692
chr12125182616125183816E07223854
chr12125183979125184260E07225217
chr12125184291125184376E07225529
chr12125184438125184713E07225676
chr12125185360125186174E07226598
chr12125186178125186308E07227416
chr12125199933125200565E07241171
chr12125200598125200652E07241836
chr12125201540125201672E07242778
chr12125201673125201885E07242911
chr12125201949125201989E07243187
chr12125202023125202126E07243261
chr12125202536125202590E07243774
chr12125202757125202830E07243995
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chr12125203849125204150E07245087
chr12125204228125204302E07245466
chr12125204418125204468E07245656
chr12125204523125206155E07245761
chr12125110137125110218E073-48544
chr12125110292125110372E073-48390
chr12125123809125124388E073-34374
chr12125135402125136193E073-22569
chr12125136240125136378E073-22384
chr12125136470125136799E073-21963
chr12125136816125136958E073-21804
chr12125136984125137167E073-21595
chr12125138971125139382E073-19380
chr12125141051125141148E073-17614
chr12125141171125141267E073-17495
chr12125141316125141448E073-17314
chr12125141486125141587E073-17175
chr12125145322125145426E073-13336
chr12125145963125146300E073-12462
chr12125146359125146558E073-12204
chr12125147707125147769E073-10993
chr12125147816125148246E073-10516
chr12125148457125148915E073-9847
chr12125150829125150890E073-7872
chr12125150892125150952E073-7810
chr12125153101125153489E073-5273
chr12125153502125153614E073-5148
chr12125158382125159152E0730
chr12125159155125159398E073393
chr12125159440125159484E073678
chr12125159495125159589E073733
chr12125159774125159894E0731012
chr12125159912125160055E0731150
chr12125160116125160223E0731354
chr12125160300125161458E0731538
chr12125161560125161676E0732798
chr12125161690125161734E0732928
chr12125161771125161960E0733009
chr12125163497125163865E0734735
chr12125163879125164024E0735117
chr12125164029125164567E0735267
chr12125164655125164857E0735893
chr12125169048125173565E07310286
chr12125174119125174709E07315357
chr12125179321125180038E07320559
chr12125180434125180732E07321672
chr12125180892125181016E07322130
chr12125181033125181115E07322271
chr12125181198125181248E07322436
chr12125181318125181610E07322556
chr12125181688125181771E07322926
chr12125181778125181964E07323016
chr12125182454125182504E07323692
chr12125182616125183816E07323854
chr12125183979125184260E07325217
chr12125184291125184376E07325529
chr12125185027125185077E07326265
chr12125185150125185315E07326388
chr12125185360125186174E07326598
chr12125203758125203817E07344996
chr12125203849125204150E07345087
chr12125204228125204302E07345466
chr12125204418125204468E07345656
chr12125204523125206155E07345761
chr12125206244125206954E07347482
chr12125110137125110218E074-48544
chr12125110292125110372E074-48390
chr12125135152125135319E074-23443
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