rs11066015

Homo sapiens
G>A
ACAD10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0014 (439/29984,GnomAD)
A=0000 (8/29118,TOPMED)
A=0036 (179/5008,1000G)
A=0001 (4/3854,ALSPAC)
A=0000 (0/3708,TWINSUK)
chr12:111730205 (GRCh38.p7) (12q24.12)
AD
GWASdb2
4   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.111730205G>A
GRCh37.p13 chr 12NC_000012.11:g.112168009G>A

Gene: ACAD10, acyl-CoA dehydrogenase family member 10(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ACAD10 transcript variant 1NM_001136538.1:c.N/AIntron Variant
ACAD10 transcript variant 2NM_025247.5:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=1.000A=0.000
1000GenomesAmericanSub694G=1.000A=0.000
1000GenomesEast AsianSub1008G=0.824A=0.176
1000GenomesEuropeSub1006G=1.000A=0.000
1000GenomesGlobalStudy-wide5008G=0.964A=0.036
1000GenomesSouth AsianSub978G=1.000A=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.999A=0.001
The Genome Aggregation DatabaseAfricanSub8728G=1.000A=0.000
The Genome Aggregation DatabaseAmericanSub838G=1.000A=0.000
The Genome Aggregation DatabaseEast AsianSub1616G=0.730A=0.270
The Genome Aggregation DatabaseEuropeSub18500G=0.999A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29984G=0.985A=0.014
The Genome Aggregation DatabaseOtherSub302G=1.000A=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.999A=0.000
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=1.000A=0.000
PMID Title Author Journal
23555315Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.Haiman CAPLoS Genet
27181629Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus.Sakiyama MSci Rep
22865593Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population.Bye HCarcinogenesis
26833210Evaluation of pleiotropic effects among common genetic loci identified for cardio-metabolic traits in a Korean population.Kim YKCardiovasc Diabetol

P-Value

SNP ID p-value Traits Study
rs110660151.73E-85alcohol (ever vs. never)23555315
rs110660154.28E-09alcohol consumption23555315

eQTL of rs11066015 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11066015 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12112121005112121049E067-46960
chr12112121293112121343E067-46666
chr12112121582112121632E067-46377
chr12112121724112121796E067-46213
chr12112121888112121937E067-46072
chr12112122047112122097E067-45912
chr12112122118112122168E067-45841
chr12112153115112153510E067-14499
chr12112153601112153651E067-14358
chr12112191009112191667E06723000
chr12112192887112192956E06724878
chr12112211077112211234E06743068
chr12112211239112211372E06743230
chr12112211459112214305E06743450
chr12112214755112214834E06746746
chr12112214875112215915E06746866
chr12112121888112121937E068-46072
chr12112122047112122097E068-45912
chr12112122118112122168E068-45841
chr12112125136112125350E068-42659
chr12112125515112125592E068-42417
chr12112152787112153106E068-14903
chr12112153115112153510E068-14499
chr12112153601112153651E068-14358
chr12112153981112154032E068-13977
chr12112178800112179005E06810791
chr12112179012112179062E06811003
chr12112179128112179480E06811119
chr12112185180112185382E06817171
chr12112185650112185847E06817641
chr12112185892112186627E06817883
chr12112186780112187002E06818771
chr12112187111112187283E06819102
chr12112187316112187529E06819307
chr12112191808112191862E06823799
chr12112191936112192017E06823927
chr12112192094112192356E06824085
chr12112192413112192846E06824404
chr12112193493112193555E06825484
chr12112193706112193829E06825697
chr12112194124112194251E06826115
chr12112194358112194424E06826349
chr12112194468112194518E06826459
chr12112194589112194676E06826580
chr12112194787112194870E06826778
chr12112194873112194955E06826864
chr12112194958112196457E06826949
chr12112196517112196597E06828508
chr12112206883112207004E06838874
chr12112207057112207139E06839048
chr12112207231112207372E06839222
chr12112211077112211234E06843068
chr12112211239112211372E06843230
chr12112211459112214305E06843450
chr12112214755112214834E06846746
chr12112121582112121632E069-46377
chr12112121724112121796E069-46213
chr12112121888112121937E069-46072
chr12112122047112122097E069-45912
chr12112122118112122168E069-45841
chr12112125136112125350E069-42659
chr12112186780112187002E06918771
chr12112191009112191667E06923000
chr12112191808112191862E06923799
chr12112191936112192017E06923927
chr12112192094112192356E06924085
chr12112192413112192846E06924404
chr12112194124112194251E06926115
chr12112194358112194424E06926349
chr12112194468112194518E06926459
chr12112194589112194676E06926580
chr12112194787112194870E06926778
chr12112194873112194955E06926864
chr12112194958112196457E06926949
chr12112206883112207004E06938874
chr12112211077112211234E06943068
chr12112211239112211372E06943230
chr12112211459112214305E06943450
chr12112121582112121632E070-46377
chr12112121724112121796E070-46213
chr12112121888112121937E070-46072
chr12112122047112122097E070-45912
chr12112122118112122168E070-45841
chr12112125136112125350E070-42659
chr12112194958112196457E07026949
chr12112206883112207004E07038874
chr12112121888112121937E071-46072
chr12112122047112122097E071-45912
chr12112122118112122168E071-45841
chr12112153115112153510E071-14499
chr12112178800112179005E07110791
chr12112179012112179062E07111003
chr12112179128112179480E07111119
chr12112191009112191667E07123000
chr12112191808112191862E07123799
chr12112191936112192017E07123927
chr12112192094112192356E07124085
chr12112192413112192846E07124404
chr12112192887112192956E07124878
chr12112194958112196457E07126949
chr12112196517112196597E07128508
chr12112203436112203528E07135427
chr12112203536112203790E07135527
chr12112206883112207004E07138874
chr12112211077112211234E07143068
chr12112211239112211372E07143230
chr12112211459112214305E07143450
chr12112214755112214834E07146746
chr12112120813112120863E072-47146
chr12112121888112121937E072-46072
chr12112122047112122097E072-45912
chr12112122118112122168E072-45841
chr12112125136112125350E072-42659
chr12112152787112153106E072-14903
chr12112153115112153510E072-14499
chr12112192094112192356E07224085
chr12112192413112192846E07224404
chr12112194468112194518E07226459
chr12112194589112194676E07226580
chr12112194787112194870E07226778
chr12112194873112194955E07226864
chr12112194958112196457E07226949
chr12112206883112207004E07238874
chr12112207057112207139E07239048
chr12112211077112211234E07243068
chr12112211239112211372E07243230
chr12112211459112214305E07243450
chr12112214755112214834E07246746
chr12112121888112121937E073-46072
chr12112122047112122097E073-45912
chr12112122118112122168E073-45841
chr12112125136112125350E073-42659
chr12112191009112191667E07323000
chr12112191808112191862E07323799
chr12112191936112192017E07323927
chr12112192094112192356E07324085
chr12112192413112192846E07324404
chr12112192887112192956E07324878
chr12112194589112194676E07326580
chr12112194787112194870E07326778
chr12112194873112194955E07326864
chr12112194958112196457E07326949
chr12112206883112207004E07338874
chr12112207057112207139E07339048
chr12112207231112207372E07339222
chr12112207485112207617E07339476
chr12112207987112208189E07339978
chr12112211077112211234E07343068
chr12112211239112211372E07343230
chr12112211459112214305E07343450
chr12112214755112214834E07346746
chr12112214875112215915E07346866
chr12112121582112121632E074-46377
chr12112121724112121796E074-46213
chr12112121888112121937E074-46072
chr12112125136112125350E074-42659
chr12112191009112191667E07423000
chr12112191808112191862E07423799
chr12112191936112192017E07423927
chr12112192094112192356E07424085
chr12112192413112192846E07424404
chr12112194124112194251E07426115
chr12112194358112194424E07426349
chr12112194468112194518E07426459
chr12112194589112194676E07426580
chr12112194787112194870E07426778
chr12112206883112207004E07438874
chr12112207231112207372E07439222
chr12112207485112207617E07439476
chr12112207987112208189E07439978
chr12112211077112211234E07443068
chr12112211239112211372E07443230
chr12112211459112214305E07443450
chr12112214755112214834E07446746
chr12112214875112215915E07446866
chr12112122047112122097E081-45912
chr12112122118112122168E081-45841
chr12112153115112153510E081-14499
chr12112184727112184805E08116718
chr12112184827112184877E08116818
chr12112185180112185382E08117171
chr12112185650112185847E08117641
chr12112185892112186627E08117883
chr12112186780112187002E08118771
chr12112187111112187283E08119102
chr12112187316112187529E08119307
chr12112191009112191667E08123000
chr12112191808112191862E08123799
chr12112191936112192017E08123927
chr12112192094112192356E08124085
chr12112192413112192846E08124404
chr12112192887112192956E08124878
chr12112193192112193259E08125183
chr12112193317112193367E08125308
chr12112193493112193555E08125484
chr12112193706112193829E08125697
chr12112194124112194251E08126115
chr12112194358112194424E08126349
chr12112194468112194518E08126459
chr12112194589112194676E08126580
chr12112194787112194870E08126778
chr12112194873112194955E08126864
chr12112194958112196457E08126949
chr12112196517112196597E08128508
chr12112196660112196779E08128651
chr12112120813112120863E082-47146
chr12112121005112121049E082-46960
chr12112121293112121343E082-46666
chr12112121582112121632E082-46377
chr12112121724112121796E082-46213
chr12112121888112121937E082-46072
chr12112122047112122097E082-45912
chr12112122118112122168E082-45841
chr12112152787112153106E082-14903
chr12112153115112153510E082-14499
chr12112185180112185382E08217171
chr12112185650112185847E08217641
chr12112185892112186627E08217883
chr12112186780112187002E08218771
chr12112187111112187283E08219102
chr12112187316112187529E08219307
chr12112192413112192846E08224404
chr12112192887112192956E08224878
chr12112194958112196457E08226949
chr12112196517112196597E08228508










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr12112122735112124415E067-43594
chr12112204096112206016E06736087
chr12112122735112124415E068-43594
chr12112204096112206016E06836087
chr12112122735112124415E069-43594
chr12112204096112206016E06936087
chr12112122735112124415E070-43594
chr12112204096112206016E07036087
chr12112122735112124415E071-43594
chr12112204096112206016E07136087
chr12112122735112124415E072-43594
chr12112204096112206016E07236087
chr12112122735112124415E073-43594
chr12112204096112206016E07336087
chr12112122735112124415E074-43594
chr12112204096112206016E07436087
chr12112122735112124415E081-43594
chr12112204096112206016E08136087
chr12112122735112124415E082-43594
chr12112204096112206016E08236087