rs11066595

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0097 (2936/29994,GnomAD)
G=0085 (2489/29118,TOPMED)
G=0120 (603/5008,1000G)
G=0058 (222/3854,ALSPAC)
G=0052 (193/3708,TWINSUK)
chr12:113544717 (GRCh38.p7) (12q24.13)
AD
GWASdb2
2   publication(s)
See rs on genome
22 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.113544717C>G
GRCh37.p13 chr 12NC_000012.11:g.113982522C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.858G=0.142
1000GenomesAmericanSub694C=0.910G=0.090
1000GenomesEast AsianSub1008C=0.817G=0.183
1000GenomesEuropeSub1006C=0.928G=0.072
1000GenomesGlobalStudy-wide5008C=0.880G=0.120
1000GenomesSouth AsianSub978C=0.900G=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.942G=0.058
The Genome Aggregation DatabaseAfricanSub8730C=0.878G=0.122
The Genome Aggregation DatabaseAmericanSub836C=0.910G=0.090
The Genome Aggregation DatabaseEast AsianSub1620C=0.760G=0.240
The Genome Aggregation DatabaseEuropeSub18506C=0.924G=0.075
The Genome Aggregation DatabaseGlobalStudy-wide29994C=0.902G=0.097
The Genome Aggregation DatabaseOtherSub302C=0.970G=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.914G=0.085
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.948G=0.052
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
19197348Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.Lowe JKPLoS Genet

P-Value

SNP ID p-value Traits Study
rs110665950.000642alcohol dependence21314694

eQTL of rs11066595 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11066595 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12113957192113957242E069-25280
chr12113939145113939205E070-43317
chr12113949009113949059E070-33463
chr12113949118113949494E070-33028
chr12113949669113949723E070-32799
chr12113956983113957170E070-25352
chr12113957192113957242E070-25280
chr12113957366113957778E071-24744
chr12113957192113957242E074-25280
chr12113957366113957778E074-24744
chr12113935537113935665E081-46857
chr12113938118113938321E081-44201
chr12113938383113938527E081-43995
chr12113938549113939139E081-43383
chr12113939145113939205E081-43317
chr12113949669113949723E081-32799
chr12113957192113957242E081-25280
chr12113957366113957778E081-24744
chr12113998312113998371E08115790
chr12113998649113999021E08116127
chr12113957192113957242E082-25280
chr12113998649113999021E08216127






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr12114029246114029627E07046724
chr12114029634114029804E07047112
chr12113952753113953576E082-28946
chr12113957787113958178E082-24344
chr12114029246114029627E08246724
chr12114029634114029804E08247112